A5030037858- Forensic Toxicology and Drug Analysis
- Psychedelics and Drug Studies
- Neurotransmitter Receptor Influence on Behavior
- Cannabis and Cannabinoid Research
- Alcohol Consumption and Health Effects
- Hormonal and reproductive studies
- Opioid Use Disorder Treatment
- Substance Abuse Treatment and Outcomes
- HIV, Drug Use, Sexual Risk
- Nicotinic Acetylcholine Receptors Study
- Crystallography and molecular interactions
- Effects and risks of endocrine disrupting chemicals
- Pharmaceutical and Antibiotic Environmental Impacts
- Spam and Phishing Detection
- Advanced Malware Detection Techniques
- Cybercrime and Law Enforcement Studies
- Smoking Behavior and Cessation
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Influenza Virus Research Studies
- History and advancements in chemistry
- Alcoholism and Thiamine Deficiency
- Poisoning and overdose treatments
- Chemical synthesis and alkaloids
- Biosensors and Analytical Detection
Centro de Investigación y Desarrollo
2012-2023
University of Cambridge
2022
International Drug Development
2021-2022
Municipal Institute for Medical Research
2004-2017
Hospital del Mar Research Institute
2016-2017
Hospital Del Mar
2008-2017
Universitat Autònoma de Barcelona
2007-2008
Barcelona Biomedical Research Park
2008
Universitat Pompeu Fabra
2004
Drug testing is a harm reduction strategy that has been adopted by certain countries in Europe. users are able to hand their drugs voluntarily for chemical analysis of composition and dose. will be alerted about dangerous test results the drug systems directly through warning campaigns. An international collaborative effort was launched combine data systems, called Trans European Information (TEDI) project. Spain, Switzerland, Belgium, Austria, Portugal, Netherlands participated this This...
4-Bromo-2,5-dimethoxyphenethylamine (2C-B) is a psychoactive analogue of mescaline that becoming increasingly popular as rave and club drug. We investigated its presence in the illicit drug market Spain, pattern use profile subjective effects. Drug material was analysed for 2C-B information on effects obtained from recreational users. Scores were statistically compared with previously collected data psychostimulants ( d-amphetamine), entactogens (MDMA) psychedelics (ayahuasca Salvia...
This paper describes the misrepresentation of LSD at Portugal's Boom Festival 2014 and prevention unintentional consumption DOx 25x-NBOMe among consumers attending a drug-checking service.Two hundred forty-five drug samples expected to contain were submitted service for chemical analysis. One ten post-test questionnaires successfully matched with test results.About 67.3% alleged tested contained only LSD; 0.8% combined adulterants; 24.1% did not but another psychoactive substance, including...
New psychoactive tryptamines may be a public health risk since they intend to mimic the hallucinogenic effects of regulated drugs. Few studies describe uses and clinical unregulated new tryptamines. This study aims (1) explore presence classified as NPS among substances delivered for analysis harm-reduction organization; (2) found in samples after analysis; (3) compare analytical results vs. non-regulated Samples analyzed by gas chromatography-mass spectrometry from 2006 2015 were included....
Abstract Synthetic cannabinoid receptor agonists (SCRAs) are a dynamic class of new psychoactive substances (NPS), with novel chemotypes emerging each year. Following the putative detection 5F‐CUMYL‐P7AICA in Australia 2016, scaffold‐hopping SCRAs 5F‐CUMYL‐PICA, 5F‐CUMYL‐PINACA, and were synthesized characterized by nuclear magnetic resonance (NMR) spectroscopy, gas chromatography–mass spectrometry (GC–MS), liquid chromatography–quadrupole time‐of‐flight–MS (LC–QTOF–MS). Since little is...
Forensic laboratories are constantly required to identify new drugs and their metabolites. N-ethylhexedrone (NEH, HEXEN), N-Ethylpentedrone (NEP), 4-Chloromethcathinone (4-CMC, clephedrone) synthetic substances structurally related natural cathinone, alkaloid present in the leaves of Catha edulis (Khat) plant. These cathinones (SC) members heterogenous family psychoactive (NPS) that raised major concerns scientific forensic communities over past years due widespread consumption. In this...
Las nuevas sustancias psicoactivas (NPS, del inglés new psychoactive substances) emulan los efectos de las drogas ilegales y son distribuidas como no aptas para consumo humano a través canales legales. Su estatus alegal, facilidad compra precio facilitan su propician una falsa percepción seguridad entre sus consumidores. En España, catinonas sintéticas el grupo más numeroso muestras NPS identificadas en servicios análisis. Existe un gran listado secundarios asociados sintéticas, algunos...
Objective The aim of this study was to describe the presence and composition cathinone derivatives (CDs) in drug samples analyzed at a Drug Testing Service. Material methods Data provided by Service Energy Control (a Spanish organization working risk reduction among recreational users) were obtained from delivered as, or containing CDs, between January 2010 June 2012. Specimens identified combining thin layer chromatography gas associated with mass spectrometry. Results Two hundred...
2,5-dimethoxy-4-bromophenethylamine (2C-B) is a psychedelic phenylethylamine derivative, structurally similar to mescaline. It serotonin 5-hydroxytryptamine-2A (5-HT2A), 5-hydroxytryptamine-2B (5-HT2B), and 5-hydroxytryptamine-2C (5-HT2C) receptor partial agonist used recreationally as new psychoactive substance. has been reported that 2C-B induces mild effects, although its acute pharmacological effects pharmacokinetics have not yet fully studied in humans. An observational study was...
Background: Drug checking is a proven harm reduction strategy and provides real-time information on the market of new psychoactive substances (NPS). It combines chemical analysis samples with direct engagement people who use drugs (PWUD), giving ability to increase preparedness responsiveness towards NPS. Next that, it supports rapid identification potential unwitting consumption. However, NPS cause toxicological battle for researchers, as factors such unpredictability quick shift complicate...
Objective To know the pattern of use new psychoactive substances (NPSs) in a Spanish sample research chemical (RC) users and to deepen RC user profile risk reduction strategies employed. Methods This study is cross‐sectional survey by means specific questionnaire. Recruitment was carried out at music festivals, non‐governmental organizations (NGOs), through announcements on an online forum. Two profiles were defined, according whether they search information forums. Results A total 230...
New psychoactive substances have been rapidly growing in popularity the drug market as non-illegal drugs. In last few years, an increment has reported on use of synthetic alternatives to heroin, opioids. Based information provided by European Monitoring Centre for Drug and Addiction, these opioids related overdoses deaths Europe North America. One is U-47700. A months ago, U-47700 was scheduled U.S. other countries, opioid derivatives appearing order replace it. compounds U-49900, analog...
Amphetamine (AMP), methamphetamine (MAMP) and 3,4-methylenedioxymethamphetamine (MDMA) occur in wastewater not only as a result of illicit consumption, but also, some cases, from prescription drug use or by direct disposal into the sewage system. Enantiomeric profiling these chiral drugs could give more insight origin their occurrence. In this manuscript, new analytical methodology for enantiomeric analysis amphetamine-like substances has been developed. The method consists solid-phase...
Abstract Background and aims Drugs sold on cryptomarkets are thought to have lower levels of adulteration higher strength compared with those sourced off‐line. The present study aimed determine whether cryptomarket off‐line‐sourced 3,4‐methylenedioxy‐N‐methamphetamine (MDMA), cocaine, amphetamine, methamphetamine lysergic acid diethylamide (LSD) differed in strength. Design setting A between‐groups design was used compare versus drugs. Regression analyses controlling for year service were...
Mephedrone (4-methylmethcathinone) is a synthetic cathinone with psychostimulant properties which remains one of the most popular new psychoactive substances (NPS). It frequently used orally and/or intranasally. To date, no studies have evaluated acute effects and pharmacokinetics after self-administration mephedrone (ingestion) intranasally (insufflation) in naturalistic conditions. An observational study was conducted to assess compare pharmacological effects, as well oral fluid (saliva)...
The consumption of synthetic cannabinoids (SCs) has significantly increased in the last decade and analysis SCs their metabolites human specimens is gaining interest clinical forensic toxicology. A pilot study been carried out using a combination an initial generation gas chromatography-mass spectrometry (GC-MS) screening method for determination JWH-122, JWH-210, UR-144) oral fluid (OF) consumers ultra-high performance liquid chromatography high resolution mass (UHPLC-HRMS) confirmatory...
Considered the β-keto analogue of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy), 3,4-Methylenedioxymethcathinone (methylone) is a synthetic cathinone. Over years, methylone has been used as substitute for conventional psychostimulants, such MDMA. To date, little known about human pharmacology methylone; only available information provided by surveys or published intoxication reports. In present observational–naturalistic study, we evaluate acute subjective and physiological effects after...