A5034981595- Forensic Toxicology and Drug Analysis
- Psychedelics and Drug Studies
- Neurotransmitter Receptor Influence on Behavior
- Cannabis and Cannabinoid Research
- Opioid Use Disorder Treatment
- Substance Abuse Treatment and Outcomes
- Mass Spectrometry Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
Medical University of Vienna
2012-2023
International Drug Development
2021
Zentrum für Labormedizin
2016-2017
Psychostimulants such as amphetamine and cocaine are illicitly used drugs that act on neurotransmitter transporters for dopamine, serotonin or norepinephrine. These can by themselves already cause severe neurotoxicity. However, an additional health threat arises from adulterant substances which added to the illicit compound without declaration. One of most frequently adulterants in street sold is anthelmintic drug levamisole. We tested effects levamisole heterologously expressed HEK293...
Background: Drug checking is a proven harm reduction strategy and provides real-time information on the market of new psychoactive substances (NPS). It combines chemical analysis samples with direct engagement people who use drugs (PWUD), giving ability to increase preparedness responsiveness towards NPS. Next that, it supports rapid identification potential unwitting consumption. However, NPS cause toxicological battle for researchers, as factors such unpredictability quick shift complicate...
The illicit consumption of psychoactive compounds may cause short and long-term health problems addiction. This is also true for amphetamines cocaine, which target monoamine transporters. In the recent past, an increasing number new with amphetamine-like structure such as mephedrone or 3,4-methylenedioxypyrovalerone (MDPV) entered market drugs. Subtle structural changes circumvent legal restrictions placed on parent compound. These novel drugs are effectively marketed "designer drugs" (also...
Purpose The 3,4-methylenedioxymetamphetamine (MDMA) content in ecstasy tablets has increased enormously throughout Europe across the past decade. This study aims to determine whether this is caused by production of “stronger” (more mg MDMA per tablet), or if have simply been getting larger and heavier tablet total). Design/methodology/approach A data set 31,716 obtained 2012–2021 10 members Trans European Drug Information (TEDI) network was analysed. Findings mass fraction remained virtually...
Synthetic cathinones comprise psychostimulants with desired effects like euphoria, increased vigilance, appetite suppression, and-mainly depending on certain structural features-entactogenic properties. 3,4-EtPV (1-(bicyclo[4.2.0]octa-1,3,5-trien-3-yl)-2-(pyrrolidin-1-yl)pentan-1-one) was first mentioned in an online drug forum September 2021, where its imminent synthesis announced. The goal to produce a legal alternative the phenylethylamines already banned by German NpSG. In February and...
Objective: N-(2-methoxy) benzyl-phenethylamine (NBOMe) derivatives have a high affinity to the serotonin receptor 2A and emerged as new psychedelic agents. We report case of 30-year-old man admitted hospital because acute ischemia left arm with clinical symptoms pallor, pulselessness, paresthesia, motoric deficit. The patient had history schizophrenia drug abuse disclosed during stay sublingual intake substance bought 25I-NBOMe night before ischemic event. Methods: Routine diagnostics...