A5082763221- COVID-19 and Mental Health
- Healthcare professionals’ stress and burnout
- Occupational Health and Burnout
- Organ Donation and Transplantation
- Grief, Bereavement, and Mental Health
- Cardiovascular Disease and Adiposity
- Cancer-related cognitive impairment studies
- Adipokines, Inflammation, and Metabolic Diseases
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Workplace Health and Well-being
- Inflammatory Biomarkers in Disease Prognosis
- Palliative Care and End-of-Life Issues
Hospital de São João
2023
Universidade do Porto
2018-2022
Faculty (United Kingdom)
2022
Centre for Health Technology and Services Research
2022
Rede de Química e Tecnologia
2018
In the last 2 weeks of January 2021, Portugal was worst country in world incidence infections and deaths due to COVID-19. As a result, pressure on healthcare system increased exponentially, exceeding its capacities leaving hospitals near collapse. This scenario caused multiple constraints, particularly for hospital medical staff. Previous studies conducted at different moments during pandemic reported that COVID-19 has had significant negative impacts workers' psychological health, including...
Urothelial carcinoma is one of the most frequently diagnosed cancer types in world and despite progress treatment, it remains a lethal disease metastatic stage. Because its high programmed cell death ligand 1 protein expression, associated with an increased response to immune checkpoints inhibitors. In past few years, gold standard for first-line treatment urothelial has been platinum-based chemotherapy, avelumab (PD-1 inhibitor) maintenance therapy non-progressing tumours. After remarkable...
The COVID-19 pandemic has had a negative impact on the mental health of healthcare workers (HCWs) worldwide. This study aims to identify degree which sociodemographic variables and indicators subjective well-being psychological resilience are associated, positively negatively, with outcomes burnout, stress, depression anxiety among Portuguese HCWs observed during first wave. It also evaluate strength association these each outcome.Cross-sectional quantitative study. statistical methods used...
The potential neurotoxic effects of anticancer drugs, like doxorubicin (DOX) and mitoxantrone (MTX; also used in multiple sclerosis), are presently important reasons for concern, following epidemiological data indicating that cancer survivors submitted to chemotherapy may suffer cognitive deficits. We evaluated the vitro neurotoxicity two commonly chemotherapeutic DOX MTX, study their underlying mechanisms SH-SY5Y human neuronal cell model. Undifferentiated cells were exposed or MTX (0.13,...
Nondipper hypertensive patients have higher levels of platelet-to-lymphocyte ratio, a new studied inflammatory biomarker in primary hypertension. Furthermore, these risk cardiovascular morbidity and mortality. This study aimed to assess the relationship between ratio pattern (dipper vs nondipper) association major adverse events.A retrospective analysis was performed. One hundred fifty-three were included classified as dipper or nondipper according 24-hour ambulatory blood pressure...
Abstract Background Organ transplantation represents the most effective and acceptable therapy for end-stage organ failure. However, its frequent practice often leads to a shortage of organs worldwide. To solve this dilemma, some countries, such as Portugal, have switched from an opt-in opt-out system, which has raised concerns about respect individual autonomy. We aimed evaluate whether young university students are aware system so that they can make informed, autonomous conscious...