A5018248264- Tuberculosis Research and Epidemiology
- Adenosine and Purinergic Signaling
- COVID-19 Clinical Research Studies
- Synthesis and Characterization of Heterocyclic Compounds
- Nanoplatforms for cancer theranostics
- Viral Infections and Immunology Research
- Healthcare Systems and Public Health
- Technology and Human Factors in Education and Health
- Medical and Biological Sciences
- Synthesis and biological activity
- Insect and Pesticide Research
- Catalytic C–H Functionalization Methods
- Viral gastroenteritis research and epidemiology
- Biochemical and Molecular Research
- SARS-CoV-2 and COVID-19 Research
- Photodynamic Therapy Research Studies
- Virology and Viral Diseases
- Cytomegalovirus and herpesvirus research
- Skin Protection and Aging
- Mosquito-borne diseases and control
- HIV/AIDS drug development and treatment
- Plant Virus Research Studies
Chumakov Institute of Poliomyelitis and Viral Encephalitides
2022-2025
Russian Academy of Sciences
2022-2025
Centre for Research and Development
2023
Sechenov University
2022-2023
Botkin Hospital
2020
The detection of “silent” poliovirus (PV) circulation among clinically healthy populations is an important component supplementary surveillance for poliomyelitis. Migrants from countries or regions where polio endemic, affected by outbreaks, at risk may contribute to the introduction PVs epidemic significance: wild type 1, vaccine-derived polioviruses (VDPVs), 2 into polio-free countries. Migrant children, refugees under 5 years age, are considered a “risk group” in Russia and subject...
Relevance. To achieve the goals of measles and rubella elimination poliomyelitis eradication programs, immunization coverage at least 95% target population is required. Objective data on state specific herd immunity are provided only by results serosurveys. In Republic Tajikistan, such monitoring not carried out regularly. Therefore, purpose study was to assess actual measles, rubella, viruses.
 Materials methods. The blood sera 563 children adults collected in 7 cities 13 districts...
Abstract Evolutionary potential of viruses can result in outbreaks well‐known and emergence novel ones. Pharmacological methods intervening the reproduction various less popular, but not important are available, as well spectrum antiviral activity for most known compounds. In framework chemical biology paradigm, characterization new compounds allows to extend space provides structure–activity relationships data‐driven drug discovery. Here we present a primary assessment spiro‐annulated...
Rose Bengal (RB) is an anionic xanthene dye with multiple useful biological features, including photosensitization properties. RB was studied extensively as a photosensitizer, mostly for antibacterial and antitumor photodynamic therapy (PDT). The application of to virus inactivation rather understudied, no derivatives have been developed antivirals. In this work, we used synthetic approach based on successful design photosensitizing antivirals produce photoinactivation. A series...
N6-Substituted adenosine derivatives are a promising class of highly biologically active compounds for the development new antivirals. However, nucleosides, along with biological activity, often exhibit high cytotoxicity. We have recently shown that introduction three biodegradable residues nicotinic acid into structure two N6-benzyladenosine (BAR) and N6-(3-fluorobenzyl)adenosine (FBAR), decreases their cytotoxicity turns out to be prospective approach further elaboration nucleoside...
The basic concepts of vocational training health professionals in the capital during a pandemic are considered. is carried out with aim improving quality qualified specialists modern knowledge and practical skills connection threat spread new coronavirus infection COVID-19.