A5063079250- Immunotherapy and Immune Responses
- Cancer-related Molecular Pathways
- RNA Interference and Gene Delivery
- Women's cancer prevention and management
- Phytochemistry Medicinal Plant Applications
- Cancer Genomics and Diagnostics
- Vestibular and auditory disorders
- Public Health in Brazil
- Balance, Gait, and Falls Prevention
- Immune Cell Function and Interaction
- Hedgehog Signaling Pathway Studies
- Laser Applications in Dentistry and Medicine
- Health, Nursing, Elderly Care
- Sports Performance and Training
- CAR-T cell therapy research
- T-cell and B-cell Immunology
- Genetic factors in colorectal cancer
- Youth, Drugs, and Violence
- Male Reproductive Health Studies
- Effects of Vibration on Health
- vaccines and immunoinformatics approaches
- Melanoma and MAPK Pathways
- Health Education and Validation
- Cancer Risks and Factors
- Occupational Health and Burnout
Universidade Estadual de Goiás
2006-2024
New York University
2024
University of the Witwatersrand
2021
National Health Laboratory Service
2021
Niigata University
2003-2019
Universidade Federal de Goiás
2004-2019
Fundação de Apoio a Pesquisa do Estado de Goiás
2012-2019
Universidade de Brasília
2019
Brazilian Research in Intensive Care Network
2017
Pontifícia Universidade Católica de Goiás
2004-2015
Objetivo: Descrever a prevalência dos transtornos mentais comuns em acadêmicos da área saúde, bem como os fatores sociodemográficos e hábitos de vida que interferem na saúde mental. Métodos: Foi realizada uma pesquisa descritiva, abordagem quantitativa, com cursos fisioterapia, educação física biomedicina Universidade Estadual Goiás, responderam sobre dados sociodemográficos, física, o Self-Reporting Questionnaire para avaliar transtorno mental comum. Resultados: A amostra foi composta por...
A Prática Baseada em Evidência (PBE) é conhecida como o uso da melhor evidência científica associado a experiência clínica do profissional, esta muito utilizada na área saúde, especialmente fisioterapia, por promover prognóstico para paciente. Porem apesar dos profissionais terem conhecimento método, não são todos que praticam. Logo objetivo deste trabalho foi identificar importância PBE profissional fisioterapeuta. Foi realizado uma revisão integrativa literatura nas bases de dados:...
This study was conducted in order to investigate the implications of R72P polymorphism TP53 gene breast cancer risk. The enlightenment this matter might provide a piece information about potential patient A meta-analysis considering large sample size from studies with conflicting results on patients. Relevant were selected PubMed and SciELO databases for data extraction statistical analysis. Database built according continent genotype frequencies, genotyping methodology. dominant models (RR...
BRAF V600E is the most common mutation in cutaneous melanomas, and has been described 30-72% of such cases. This results substitution valine for glutamic acid at position 600 protein, which consequently becomes constitutively activated. The present study investigated frequency its clinical implications a group 77 primary melanoma patients treated cancer reference center Brazil. Mutation analysis was accomplished by polymerase chain reaction, restriction fragment length polymorphism,...
Hancornia speciosa GOMES is a Cerrado species widely used in food production, and because it presents several active compounds, the identification of potential candidates treatment diseases one most approaches drug research development. The aim study was to perform virtual screening compounds from H. evaluate silico antitumor breast cancer. In this focus investigate biocompounds found leaves, therefore databases Sciencedirect Pubmed were consulted, using descriptors "Hancornia speciosa" AND...
Dendritic cells are potent antigen-presenting derived from CD34+ haemopoietic stem cells. have been reported to be generated in granulocytic lineage as well monocytes, blood dendritic cell precursors and lymphoid progenitors. In order explore the differentiation pathway of applicability leukaemia-derived for anti-leukaemic immunotherapy acute leukaemia origin, we tried generate a patient with promyelocytic (APL). Leukaemia were cultured GM-CSF, IL-4 TNF-alpha 10 days. Azurophilic...
Dendritic cells (DCs) are potent antigen presenting and possess a direct anti-tumor cytotoxic ability. Nevertheless, the mechanism of cytotoxicity by DCs methods for its evaluation not fully elucidated. In order to clarify this cytotoxicity, we examined ability 1) suppress [3H] thymidine (3H-TdR) uptake tumor cells; 2) induce cytolysis on 51Cr-labeled 3) DNA fragmentation 3H-TdR labeled (JAM test). Cytolysis markers necrotic apoptotic mechanisms in vitro, respectively. inhibited...
ABSTRACT Purpose: to identify, in the literature, factors associated with development of vestibular dysfunctions individuals type 2 diabetes mellitus (DM2). Methods: an integrative review whose survey was conducted databases ISI, SciELO, LILACS and PubMed, using following descriptors: “type mellitus”, “vertigo”, “dizziness”, “vestibular diseases". Articles published last 10 years that answered research question (“What are disorders DM2?”) were included study. Results: search returned 426...
The TK6 lymphoblastoid cell line is known to be mismatch repair (MMR) and p53 proficient. Deficiency in MMR results a mutator phenotype characterized by microsatellite instability (MSI) increased hprt mutant frequency (MF). Increased MF also biomarker of effect for exposure ionizing radiation. In order test if could induced low doses gamma radiation, an cloning assay MSI investigation were performed after radiation exposure. spontaneous was 1.6 x 10-6. groups exposed 0.2, 0.5 1.0 Gy had MFs...
Vestibular dysfunctions normally manifest as dizziness, which is characterized by a subjective body balance disturbance. The present study aimed to analyze the influence of women’s self-perception level dizziness on their postural behavior. This cross-sectional research was conducted with women 30 years old or more complaint for at least three months. Anthropometric data were collected, well information and static control assessment (both eyes open closed). descriptive inferential analyses...
Introdução: Observa-se que o uso de plantas medicinais entre pacientes em tratamento anticâncer pode ser realizado na expectativa minimizar a progressão da doença ou colaborar contra os efeitos adversos terapia, no entanto, informações científicas validam seguro são extrema relevância. Objetivo: buscar evidências literatura sobre atividade antineoplásica do Cerrado citadas trabalhos científicos com oncológicos. Metodologia: As espécies foram previamente selecionadas partir 2 realizados...
Stryphnodendron adstringens, called ‘barbatimão’, is used in Brazilian folk medicine given its healing, astringent, anti-inflammatory, and antimicrobial properties. However, data on safe use remain inconclusive due to controversy about the risk posed by ethnopharmacological intake human health. Thus, present study aims quantify main classes of compounds found S. adstringens bark powder investigate biological activity ‘barbatimão’ decoction against pathogenic bacterial strains. We also...
Saúde mental é o bem-estar global, que permite as pessoas gerenciem os pensamentos, emoções, comportamentos e interações com outros, fatores sociais, culturais, econômicos políticos. Oposto a isto, transtorno uma perturbação clínica, de amplos problemas diversos sintomas, em todos âmbitos vida, gera alteração biológica psicológica, capaz gerar familiares, sociais ocupacionais muitas vezes necessário utilização psicotrópicos. Dessa forma objetivo do trabalho foi identificar psicotrópicos...
RESUMO Este estudo teve como objetivo investigar os fatores preditores para o risco de quedas e preocupação em cair mulheres adultas idosas com tonturas. O delineamento do foi tipo transversal. A amostra composta por idade mínima 50 anos queixa tontura recorrente nos últimos três meses. Foram submetidas à avaliação da capacidade cognitiva, sofrer quedas, nível tontura, qualidade vida análise das pressões plantares. descritiva inferencial dos dados realizada meio SPSS® versão 23.0. Os escores...
ABSTRACT This study aimed to investigate the predictive factors for risk of falls and fear falling in adult older women with dizziness by a cross-sectional design. Its sample included aged at least 50 years who had complaints recurrent previous three months. Their cognitive skills, falling, level, quality life, plantar pressure were assessed. Descriptive inferential analysis data performed on SPSS ® , version 23.0. Clinical test scores subjected Kolmogorov-Smirnov normality independently...
Abstract Background As at end of July 2021, the COVID-19 pandemic has been less severe in sub-Saharan Africa than elsewhere. In Malawi, there have two subsequent epidemic waves. We therefore aimed to describe dynamics SARS-CoV-2 exposure Malawi. Methods measured seroprevalence anti-SARS-CoV-2 antibodies among randomly selected blood donor sera Malawi from January 2020 February 2021. a subset, we also assesed vitro neutralisation against original variant (D614G WT) and Beta variant. Findings...