A5004687664- Natural product bioactivities and synthesis
- Ginger and Zingiberaceae research
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Biological Activities
- Bioactive Compounds and Antitumor Agents
- Phytochemical Studies and Bioactivities
- Phytochemistry and biological activity of medicinal plants
- Essential Oils and Antimicrobial Activity
- Natural Compound Pharmacology Studies
- Phytochemistry and Bioactive Compounds
- Alkaloids: synthesis and pharmacology
- Phytochemistry and Bioactivity Studies
- Synthesis of Organic Compounds
- Traditional and Medicinal Uses of Annonaceae
- Ethnobotanical and Medicinal Plants Studies
- Helicobacter pylori-related gastroenterology studies
- Natural Antidiabetic Agents Studies
- Plant-based Medicinal Research
- Chemical synthesis and alkaloids
- Piperaceae Chemical and Biological Studies
- Biological Activity of Diterpenoids and Biflavonoids
- Morinda citrifolia extract uses
- Sesquiterpenes and Asteraceae Studies
- Curcumin's Biomedical Applications
- Drug-Induced Hepatotoxicity and Protection
Chiang Mai University
2012-2022
Mahidol University
2016
Center for Innovation
2010
Prince of Songkla University
2009-2010
Silpakorn University
2008
Chulabhorn Research Institute
2003
Leiden University
1990
This study investigated some pharmacological properties of virgin coconut oil (VCO), the natural pure from [Cocos nucifera Linn (Palmae)] milk, which was prepared without using chemical or high-heat treatment. The anti-inflammatory, analgesic, and antipyretic effects VCO were assessed. In acute inflammatory models, showed moderate anti-inflammatory on ethyl phenylpropiolate-induced ear edema in rats, carrageenin- arachidonic acid-induced paw edema. exhibited an inhibitory effect chronic...
Psoriasis is a common immune‐mediated chronic inflammatory skin disease characterized by thick and erythema raised plaques with adherent silvery scales. T‐cells are activated via the IL‐23/Th17 axis which involved in psoriasis pathogenesis. Conventional treatments of have adverse events that influence patients’ adherence. Wannachawee Recipe (WCR) Thai traditional medicine known to be effective for patients; however, preclinical evidence still lacking. This study investigated therapeutic...
Bioassay-guided fractionation of a hexane extract the rhizomes Curcuma xanthorrhiza Roxb. (Zingiberaceae) led to isolation three non-phenolic diarylheptanoids, identified mainly by high-field 1H-NMR as trans-trans-1,7-diphenyl-1,3-heptadien-4-one (alnustone), trans-1,7-diprienyl-1-hepten-5-ol, and trans,trans-1,7-diphenyl-1,3-heptadien-5-ol. The latter is reported for first time plant constituent. Germacrone, curzerenone, cinnamaldehyde were also isolated identified. diarylheptanoids all...
A new tetraoxygenated xanthone, cowaxanthone F (1), as well four known compounds, morelloflavone (2), volkensiflavone (3), morelloflavone-7″-O-glucoside (fukugiside, 4), and 1,6-dihydroxyxanthone (5), were isolated from the crude acetone extract of twigs Garcinia cowa (Guttiferae). All compounds (1–5) tested for antioxidant activity against DPPH (diphenylpicrylhydrazyl), hydroxyl, superoxide radicals; only (2) (4) exhibited high potency. Eight xanthones fruits G. , cowaxanthones A–D (6–9),...
The anti-inflammatory activity of 5,7-dimethoxyflavone (5,7-DMF) has been assessed. It was found to possess a comparable effect aspirin on the rat paw edema model, and it showed no inhibition cotton pellet-induced granuloma formation. On pleurisy 5,7-DMF exhibited an antiexudative effect, interfered with leukocyte migration, markedly inhibited prostaglandin biosynthesis. In addition, cuased marked lowering rectal temperature rats. results obtained from Hippocratic screening revealed that...