A5060086619- Particle accelerators and beam dynamics
- Particle Accelerators and Free-Electron Lasers
- Superconducting Materials and Applications
- Gyrotron and Vacuum Electronics Research
- Nuclear Physics and Applications
- Radiation Effects and Dosimetry
- Radiation Therapy and Dosimetry
- Graphite, nuclear technology, radiation studies
- Medical Imaging Techniques and Applications
- Medical Device Sterilization and Disinfection
- Radiation Detection and Scintillator Technologies
- Advanced Radiotherapy Techniques
- Particle Detector Development and Performance
- Boron Compounds in Chemistry
- Nuclear reactor physics and engineering
- Wireless Power Transfer Systems
- Biosimilars and Bioanalytical Methods
- Radiation Dose and Imaging
- Nuclear and radioactivity studies
- Crystallography and Radiation Phenomena
- Nuclear Materials and Properties
- Particle physics theoretical and experimental studies
- Autophagy in Disease and Therapy
- Infrared Target Detection Methodologies
- Advanced Semiconductor Detectors and Materials
Fermi National Accelerator Laboratory
2011-2024
The Medical Device (United Kingdom)
2024
Government of the United States of America
2022
Fermi Research Alliance
1999-2010
Rush University
2008
Northern Illinois University
2007
Saint Joseph Hospital
2000
University of Illinois System
1989
We report on an experimental demonstration of electron cooling high-energy antiprotons circulating in a storage ring. In our experiments, cooling, well-established method at low energies ($<500\text{ }\text{ }\mathrm{MeV}/\mathrm{\text{nucleon}}$), was carried out new region beam parameters, requiring multi-MeV dc and unusual transport line. this Letter, we present the results longitudinal force measurements compare them with theoretical predictions.
The sterilization of medical devices using the gamma rays from decay cobalt-60 has accumulated decades experience performance materials and that are irradiated. use radiation electron beams x-rays much less this leads to questions equivalency between these three technologies. Computer simulations were conducted model relevant physical processes interactions each forms in order compare spectra energies at below 500 keV. It is predominantly electrons threshold produce dose. No difference...
Several high efficiency, low cost, RF sources are in development or recently completed. All designed to provide operating efficiencies exceeding 80% and more than 100 kW of output power with a focus on average CW operation. The include (1) magnetron system amplitude phase control, multiple beam, grid-tube based source, beam inductive tube, klystron using the core oscillation method. estimated cost for source one dollar per Watt 75 cents Watt, respectively. Operating frequencies span range...
Abstract Accelerators for High Energy Physics (HEP) are large users of energy, much it in the form radiofrequency (RF) power to accelerate particles very high energies. Proposed HEP projects will require even larger amounts RF energy. Increasing concerns cost and availability energy community use as efficeintly possible. Successful transfer technology public private sectors be most effective if is highly efficient. Historically, has utilized available sources, mainly vacuum tube technology,...
A proof of principle for cell killing by Gadolinium (Gd) neutron capture in Magnevist preloaded Glioblastoma multiforme (GBM) cells is provided.U87cells were pre-loaded with 5 mg/ml (Gd containing compound) and irradiated using an enhanced beam developed at NIU Institute Neutron Therapy Fermilab. These experiments possible because fast therapy assembly designed to use the Fermilab deliver a greater fraction thermal neutrons development improved calculations dose beam. Clonogenic response was...
To establish metabolic context for radiation sensitivity by measuring autophagic flux in two different glioblastoma (GBM) cell lines. Clonogenic survival curve analysis of U87 or U251 cells exposed to γ radiation, fast neutrons, a mixed energy neutron beam (METNB) Auger electrons from gadolinium capture (GdNC) reaction suggested other factors, beyond defective DNA damage response, contribute death cells. Altered tumor metabolism (autophagy) was hypothesized as factor cells' clonogenic...
The first stage of the Fermilab Electron Cooling R&D program is now complete: technology necessary to generate hundreds milliamps electron beam current at MeV energies has been demonstrated. Conceptual design studies show that with an 200 mA and a cooling section 20 m in Recycler ring can provide antiproton stacking rates suitable for Tevatron upgrades beyond Run II luminosity goals. A prototype such system being built as part continuing program. This paper describes well status
A 4.3-MeV electron cooling system [1] has been installed at Fermilab in the Recycler antiproton storage ring and is currently being commissioned. The designed to assist accumulation of 8.9-GeV/c antiprotons for Tevatron collider operations. This paper reports on progress beam commissioning effort as well detailed plans demonstrating antiprotons.
PURPOSE: To evaluate neutron irradiation alone and with chemotherapy to treat inoperable pancreatic cancer. MATERIALS AND METHODS: Between 1977 1994, 173 patients (60 men, 113 women, aged 43-77 years [mean, 59 years]) unresectable adenocarcinoma of the exocrine pancreas were treated, 106 67 concomitant (fluorouracil [5-FU]). At follow-up, which was performed at 2-month intervals until death (range, 4-64 months), clinical status recorded, noting presence overt metastasis onset any major...
The Illinois Accelerator Research Center (IARC) hosts a new accelerator development program at Fermi National Laboratory. IARC provides access to Fermi's state-of-the-art facilities and technologies for research, industrialization of particle technology. In addition facilitating available existing infrastructure, the Campus has dedicated 36,000 ft2 Heavy Assembly Building (HAB) with all infrastructure needed develop, commission operate accelerators. Connected HAB is 47,000 Office, Technology...
HgCdTe-based FPAs that can be used in high neutron radiation environments were designed and fabricated by EPIR, tests using Fermi National Accelerator Laboratory's beam confirmed these maintain imaging functionality while exposed to fluxes up low-1E13 per squared centimeter accumulated exposure. Monte Carlo N-Particle (MCNP) simulations find the energy deposited into HgCdTe FPA come from not only directly impinging neutrons but also scattered subsequently generated protons, electrons...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation Linda Yasui, Samantha Gladden, Christine Andorf, Thomas Kroc; Fast Neutron Induced Autophagy Leads To Necrosis In Glioblastoma Multiforme Cells. AIP Conf. Proc. 1 June 2011; 1336 (1): 377–382. https://doi.org/10.1063/1.3586124 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley...
The medical device is in dire need of a long-term solution for the sterilization crisis. In this panel we'll hear from experts who are bringing new approaches to challenge making devices safe.
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