A5025609612- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Urinary Tract Infections Management
- Prostate Cancer Diagnosis and Treatment
- Urological Disorders and Treatments
- Bladder and Urothelial Cancer Treatments
- Anorectal Disease Treatments and Outcomes
- Prostate Cancer Treatment and Research
- Pediatric Urology and Nephrology Studies
- Pelvic and Acetabular Injuries
- Gut microbiota and health
- Reproductive tract infections research
- Urologic and reproductive health conditions
- Renal cell carcinoma treatment
- Urinary and Genital Oncology Studies
- Venous Thromboembolism Diagnosis and Management
- Sexual function and dysfunction studies
- Hernia repair and management
- Renal and related cancers
- Hormonal and reproductive studies
- Cardiac, Anesthesia and Surgical Outcomes
- Ureteral procedures and complications
- Clinical Reasoning and Diagnostic Skills
- Artificial Intelligence in Healthcare and Education
- Cancer survivorship and care
Universidad de Salamanca
2015-2025
Instituto de Investigación Biomédica de Salamanca
2012-2025
Complejo Hospitalario de Salamanca
2008-2024
Hospital Universitario de Getafe
2024
Instituto de Investigación Biosanitaria de Granada
2019
Biomedical Research Institute
2015
University of Miami
2003-2004
Universität Hamburg
2004
Sylvester Comprehensive Cancer Center
2004
The identification of accurate bladder tumor markers/tests could improve diagnosis, recurrence monitoring and treatment in patients with cancer. In this study we compared the efficacy hyaluronic acid (HA)-hyaluronidase (HAase), BTA-Stat (Bard/Bion Diagnostics, Redmond, Washington), Hemastix (Bayer Corp., Elkhart, Indiana) (hematuria detection) UBC-Rapid (IDL Biotech, Borlänger, Sweden) tests, cytology to detect HA-HAase test measures urinary HA HAase levels, detects complement factor-H H...
Urinary tract infections (UTIs) are considered the most common bacterial infections, especially in women. The objective of this study was to evaluate use sublingual vaccine Uromune® order prevent recurrent UTIs (RUTIs). This conceived as a multicenter observational study. clinical history 319 women who presented at least 2 episodes UTI last 6 months or 3 12 reviewed. Data related treatment and evolution were recorded analyzed. A total 159 patients received prophylactic with for period (group...
Objective: To evaluate the clinical impact of prophylactic treatment with sublingual immunostimulation in prevention recurrent urinary tract infections (rUTIs) compared use antibiotics. Material and Methods: Retrospective cohort study evaluating records 669 women rUTIs; 339 had a 6-month prophylaxis antibiotics 360 3-month bacterial preparation (MV 140-Uromune®). The time after prophylaxis-period until appearance new infection (assessed by uroculture) was scored during one year. Absolute...
BackgroundRecurrent urinary tract infections (UTIs), which consist of three or more episodes in 1 year two 6 months, affect 5% to 10% women. MV140, a sublingual preparation whole-cell inactivated bacteria, has shown clinical benefit observational studies. This trial examined treatment with MV140 prevent recurrent UTI.MethodsIn this multicenter, randomized, double-blind, placebo-controlled, parallel-group 1-year trial, 240 women 18 75 years age from Spain and the United Kingdom UTI were...
To determine the variations in costs of prophylaxis recurrent urinary tract infections (RUTIs) among different prevention protocols, a prospective observational multicenter study on 1614 women receiving RUTI was conducted. The patient groups were as follows: Group A (n = 444): conventional suppressive antibiotic therapy; V 732): polyvalent bacterial vaccine; and O 438): other adjuvant measures. variables age, body mass index, American Society Anesthesiologists (ASA) physical status...
Abstract Introduction and hypothesis In randomized clinical trials onabotulinumtoxinA was demonstrated to be an effective well-tolerated treatment for overactive bladder (OAB) with urinary incontinence (UI). However, data reporting use in everyday practice are limited. Here, we present the results from a large, first-of-its-kind real-world study patients OAB. Methods This prospective, observational, multinational (GRACE; ClinicalTrials.gov , NCT02161159) performed four European countries....
Introduction: High performance female athletes may be a risk group for the development of urinary incontinence due to imbalance forces between abdomen and pelvis. Pelvic floor physiotherapy useful treatment in these patients. Objectives: (1) To identify scientific evidence pelvic (PF) dysfunctions that are associated with (UI) high-performance sportswomen. (2) determine whether (PT) corrects UI elite athletes. Materials methods: Meta-analysis published evidence. The articles analyzed were...
The aim of the current study was to determine demographic characteristics and risk factors associated with male urinary incontinence (UI) assess effectiveness effect on quality-of-life a pelvic floor muscle training (PFMT) protocol electromyography-biofeedback (EMG-BFB) surface electrodes. A prospective, quasi-experimental before-and-after sample 61 men out 372 patients referred Pelvic Floor Unit from October 2005 June 2012 performed. consisted 20 sessions EMG-BFB supervised by...
Bacteriuria may affect the response to adjuvant therapy in non-muscle invasive bladder cancer (NMIBC). The main aim of this study was examine effect recurrent bacteriuria (RB) on prognosis NMIBC women receiving intravesical therapy.
Ischemia-reperfusion injury (IRI) remains a major problem in renal transplantation, and the inflammatory response to IRI exacerbates resultant injury. We have investigated whether systemic administration of cardiotrophin-1 (CT-1) is able improve function decrease responses rat model IRI.IRI was induced by pedicle clamping (60 min) followed reperfusion contralateral nephrectomy. CT-1 injected through penile vein 30 min before release its effects were compared with saline-treated group at five...
This study aimed to determine the effectiveness of whole-cell bacterial immunotherapy, i.e. MV140 and autovaccines, in reducing number ofurinary tract infections (UTIs)in frail elderly patients with recurrent UTI (RUTI).A prospective cohort observational was performed including 200 subjects suffering RUTI, both females males, between 2016 2018. The autovaccines polybacterial formulation (Uromune®), consisting ofwhole-cell heat-inactivated Escherichia coli25%, Klebsiella pneumoniae25%,...
Prostate-specific antigen velocity (PSAV) is used to monitor men with clinical suspicion of prostate cancer (PCa), a normal cut-off point 0.3-0.5 ng/mL/year. The aim the study establish predictive capacity PSAV (value and acceleration) free PSA/total PSA index or ratio. Prospective multicentre observational in 2035 over 47 years age. who wished be informed on health their prostate. previously diagnosed condition. Groups: GA: (n = 518): serum equal greater than 2.01 ng/mL. GB: 775): 0.78...
Ureteritis cystica is an uncommon cause of acute renal pain. The aetiology remains unclear and the diagnosis may be difficult to establish. We report case a 29 year old woman with history repeated urinary tract infections presenting colic in absence lithiasis. review diagnostic tools available make recent pertinent literature.
Introduction: Mental disorders, smoking, or alcoholism and benign prostate disease are highly prevalent in men. Aims: To identify the relationship between mental disease. Methodology: A prospective multicenter study that evaluated health status 558 men from community. Groups: GP—men who request a examination whose medical history includes disorder, prior to diagnosis of disease; GU—men alcoholism. Variables: age, body mass index (BMI), specific antigen (PSA), follow-up smoking alcoholism,...
Introduction: The protocol for deceased donor kidney transplants has been standardised. procedure a living peculiarities derived from the differences in graft. When program is implemented, changes occur both profile of transplant candidate and postoperative treatments. Aims: To discover whether influences functional outcomes grafts longstanding classical to identify factors associated with outcomes. Methods: Retrospective observational multicentre study. Sample: Kidney patients two urology...
Paragangliomas are usually benign tumors arising from chromaffin cells located outside the adrenal gland. Prostatic paraganglioma is an unusual entity in adult patients, with only 10 cases reported medical literature.A 34-year-old male a history of chronic prostatitis consulted for perineal pain. On digital rectal examination prostate was enlarged and firm, without nodules. The PSA level 0.8 ng/mL catecholamines urine were elevated. ultrasound retrovesical 9 cm mass undetermined origin...