A5001173057- Renal and related cancers
- Extracellular vesicles in disease
- Acute Kidney Injury Research
- Redox biology and oxidative stress
- Colorectal Cancer Surgical Treatments
- Nuclear Receptors and Signaling
- Gastric Cancer Management and Outcomes
- RNA Interference and Gene Delivery
- Potassium and Related Disorders
- Ferroptosis and cancer prognosis
- Retinoids in leukemia and cellular processes
- Parathyroid Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- 14-3-3 protein interactions
- Alzheimer's disease research and treatments
- Curcumin's Biomedical Applications
- Adipose Tissue and Metabolism
- Sirtuins and Resveratrol in Medicine
- Epigenetics and DNA Methylation
- Microtubule and mitosis dynamics
- Renal cell carcinoma treatment
- Magnesium in Health and Disease
- Kruppel-like factors research
Suzhou Municipal Hospital
2022
Nanjing Medical University
2022
First Affiliated Hospital of Jinan University
2020-2022
Wuhan No.1 Hospital
2018
82th Hospital of Pla
2017
117th Hospital of People's Liberation Army
2014-2015
Diabetes mellitus is closely correlated with disc degeneration. Nucleus pulposus (NP) cell apoptosis and senescence are typical cellular features within the degenerative disc. Resveratrol a newly identified phytoalexin that has protective effects on cartilaginous tissue.
Ovarian cancer is one of the deadliest gynecological malignancies in women. Chemoresistance has been a major obstacle for ovarian treatment. Zinc finger E-box-binding homeobox 1 (ZEB1) an important regulator tumor development various types cancer. Abnormal expression SLC3A2 (CD98hc), type 2 transmembrane cell surface molecule, described several cancers. This study was designed to investigate role ZEB1 and chemoresistance cisplatin cells. We found that increased cisplatin-resistant SKOV3/DPP...
Acute kidney injury (AKI) is a susceptible factor for chronic disease (CKD). There still lack of effective prevention methods in clinical practice. This study investigated the protective effect urinary exosomes from premature infants on cisplatin-induced acute injury. Here we isolated fresh urine infants. A C57BL/6 mice model was given 100 ug 24 hours after establishment. The kidneys were collected pathological examination and evaluation renal tubular damage apoptosis. In vitro experiment,...
The present techniques of clinical and histopathological diagnosis hardly distinguish chromophobe renal cell carcinoma (ChRCC) from oncocytoma (RO). To identify differentially expressed genes (DEGs) as effective biomarkers for prognosis ChRCC RO, three mRNA microarray datasets (GSE12090, GSE19982, GSE8271) were downloaded the GEO database. Functional enrichment analysis DEGs was performed by DAVID. STRING Cytoscape applied to construct protein-protein interaction (PPI) network key modules...
Apoptosis signal-regulating kinase 1–interacting (ASK1-interacting) protein-1 (AIP1) is a newly identified novel member of the Ras GTPase-activating protein family, which has been implicated in cell growth inhibition and apoptosis. However, effects AIP1 Alzheimer’s disease (AD) are unknown. In present study, we found that was elevated brain AD Tg2576 mice Aβ1-42 treated cerebral microvascular endothelial cells (CECs). treatment induced interaction apoptosis 1 (ASK1), led to dissociation ASK1...
Previous studies have reported that serum magnesium (Mg) deficiency is involved in the development of heart failure, particularly patients with end-stage kidney disease. The association between Mg levels and mortality risk receiving hemodialysis controversial. We aimed to estimate prognostic value concentration on all-cause cardiovascular hemodialysis.We did a systematic literature search PubMed, EMBASE, Cochrane Library, Web Science identify eligible among hemodialysis. performed...
Aim: Acute kidney injury (AKI), a global public health issue, not only causes millions of deaths every year, but is also susceptible factor for chronic disease (CKD). Nephrotoxic drugs are an important cause AKI. There still lack effective and satisfactory prevention method in clinical practice. This study investigated the protective effect exosomes derived from urine premature infants on cisplatin-induced acute injury. Methods: Isolation fresh infants: The characteristics were determined by...