- Global Cancer Incidence and Screening
- Acute Lymphoblastic Leukemia research
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Childhood Cancer Survivors' Quality of Life
- Diet, Metabolism, and Disease
- Neuroblastoma Research and Treatments
- Epigenetics and DNA Methylation
- Food Security and Health in Diverse Populations
- Air Quality and Health Impacts
- Occupational and environmental lung diseases
- Radiomics and Machine Learning in Medical Imaging
- Cancer Risks and Factors
- Primary Care and Health Outcomes
- Pesticide Exposure and Toxicity
- Agriculture and Farm Safety
- Smoking Behavior and Cessation
- Traumatic Brain Injury Research
- Neonatal Health and Biochemistry
- Esophageal Cancer Research and Treatment
- Metabolomics and Mass Spectrometry Studies
- Chronic Disease Management Strategies
University of Nebraska Medical Center
2022-2025
Nebraska Medical Center
2023
Pediatric cancer mortality rates have steadily declined since 2009, but over a thousand deaths still occur annually. While existing research highlights the effects of race/ethnicity and rurality on overall survival, few studies specifically analyzed these factors in relation to early mortality, defined as death within 12 months diagnosis. This study utilized SEER Research Plus Limited-Field Data (2000-2021) examine association between race/ethnicity, rurality, pediatric patients. A cohort...
Background Non-alcoholic fatty liver disease (NAFLD) ranks first among diseases in Western countries. NAFLD is typically associated with obesity and diabetes, however it also develops lean individuals without metabolic syndrome. The prevalence of 7 percent the U.S. 25–30 some Asian starts excess fat accumulation (NAFL), progresses to nonalcoholic steatohepatitis (NASH), cirrhosis hepatocellular carcinoma (HCC). pathogenesis NASH-HCC how differs from obese not well understood. Methods In this...
Nonalcoholic fatty liver disease affects about 24% of the world's population and may progress to nonalcoholic steatohepatitis (NASH), cirrhosis, hepatocellular carcinoma (HCC). While more common in those that are obese, NASH-HCC can develop lean individuals. The mechanisms by which HCC develops role epigenetic changes context obesity normal weight not well understood.In this study, we used previously generated mouse models obese using a choline deficient/high trans-fat/fructose/cholesterol...
Abstract Objectives: Social determinants of health are understudied in the context pediatric cancer. Persistent poverty, a measure developed by National Cancer Institute and US Department Agriculture’s Economic Research Service, is defined as having 20% or more an area’s population lived below poverty level for period about 30 years. The effect persistent on cancer outcomes not well understood. Methods: This population-based longitudinal study uses data from Surveillance, Epidemiology, End...
Background/Objectives: Stool-based tests, such as the fecal immunochemical test (FIT), have been widely used for increasing colorectal cancer (CRC) screening. Small media, printed materials or flyers, are known to be an effective intervention increase CRC screening by tests. However, more evidence is needed determine whether small media in improving uptake of a mailed FIT targeted at rural populations USA. Methods: In this randomized study, 1230 kits were from July December 2022 Nebraskans...
Abstract Purpose Previous studies on cancer risk among agricultural producers have focused occupational exposures, with only a few examining behavioral factors. The aim of this study was to understand risky and preventative behaviors the large farming population in Nebraska. Methods A statewide cross‐sectional farmers Nebraska aged 19 older conducted 2019 ( n = 782). Multivariable logistic regression used examine factors associated being up date screening preventive behaviors. Findings...
Abstract Even though racial, rural-urban and socioeconomic disparities have been identified in pediatric neuroblastoma incidence rates, the exact measurement of is rarely done. The study was conducted to generate summary measures evaluate health age-adjusted rates neuroblastoma. We used Surveillance, Epidemiology, & End Results (SEER) 17 registries data from 2000 2020 identify cases, race ethnicity, area residence, median income calculate rates. then HD*Calc software trends range...