A5003268069- Clostridium difficile and Clostridium perfringens research
- COVID-19 Clinical Research Studies
- Forensic and Genetic Research
- Neurological Disease Mechanisms and Treatments
- Vitamin C and Antioxidants Research
- Acute Ischemic Stroke Management
- Cardiovascular Health and Risk Factors
- Coronary Interventions and Diagnostics
- Neuroinflammation and Neurodegeneration Mechanisms
- Forensic Anthropology and Bioarchaeology Studies
- Stroke Rehabilitation and Recovery
- Public Health Policies and Education
- Anatomy and Medical Technology
- Philippine History and Culture
- COVID-19 and healthcare impacts
- Injury Epidemiology and Prevention
- Service-Oriented Architecture and Web Services
- Diphtheria, Corynebacterium, and Tetanus
- Pharmacological Receptor Mechanisms and Effects
- Mast cells and histamine
- Burn Injury Management and Outcomes
- Advancements in Transdermal Drug Delivery
- Health disparities and outcomes
- Heme Oxygenase-1 and Carbon Monoxide
- History of Medical Practice
Charleston Area Medical Center
2019-2022
CAMC Health Education and Research Institute
2020
Hope Center for Neurological Disorders
2017-2018
Washington University in St. Louis
2017-2018
Wayne State University
2018
Wake Forest University
2005
University of Edinburgh
1935
Significance Alzheimer’s disease (AD) is the most common cause of dementia and a major public health problem for which there currently no disease-modifying treatment. There an urgent need greater understanding molecular mechanisms underlying neurodegeneration in patients to create better therapeutic options. Recently, genetic studies uncovered novel AD risk variants microglial receptor, triggering receptor expressed on myeloid cells 2 (TREM2). Previous suggested that loss TREM2 function...
One of the hallmarks Alzheimer's disease is presence extracellular diffuse and fibrillar plaques predominantly consisting amyloid-β (Aβ) peptide. Apolipoprotein E (ApoE) influences deposition amyloid pathology through affecting clearance aggregation monomeric Aβ in brain. In addition to influencing metabolism, increasing evidence suggests that apoE microglial function neurodegenerative diseases. Here, we characterize impact has on innate immune response APPPS1ΔE9 APPPS1-21 transgenic mice....
ABSTRACT Endobronchial valves have a variety of potential applications, from lung volume reduction in patients with severe emphysema to closing cavities those drug‐resistant tuberculosis. This report presents two cases which endobronchial were effectively used treat pneumomediastinum.
An excavation conducted at Harewood Cemetery to identify the unmarked grave of Samuel Washington resulted in discovery burials presumably belonging George Washington's paternal grandnephews and their mother, Lucy Payne. To confirm identities this study examined Y-chromosomal, mitochondrial, autosomal DNA from a living descendant. The burial's Y-STR profile was compared FamilyTreeDNA's database, which one-step difference descendant an exact match another Washington. A more complete Y-SNP...
This study assessed the usefulness of DNA quantification to predict success historical samples when analyzing SNPs, mtDNA, and STR targets. Thirty burials from six contexts were utilized, ranging in age 80 800 years postmortem. Samples underwent library preparation hybridization capture with two bait panels (FORCE mitogenome), typing (autosomal Y-STR). All 30 generated small (~80 bp) autosomal target qPCR results, despite mean mappable fragments 55-125 bp. The results positively correlated...
Summary Experiments are described in which the natural immunity reactions of blood and cutaneous to injected toxins were studied relation known variations diet. A caloric dietary deficiency was found decrease both haemolytic activity sheep serum towards rabbit erythrocytes its complementing power, but increase agglutinating action with B. abortus (Hog). The reaction intradermal toxin tests employed unaffected. Cod liver oil calcium had no effect on nor used.
This paper explores the construction of Āmānnisā Khan (1526–1560) as a Uyghur culture hero through creation and repetition narrative linking her to Twelve Muqams. The shows intertextual linkages between various forms in which is represented, including written histories, stage play, tomb, film, novel, portraiture. analysis reveals that it frequent recontextualization “Āmānnisā collector organizer,” was first inserted into life story 1980s, has been most significant element developing image.
Abstract: Drug reaction with eosinophilia and systemic symptoms (DRESS) is a potentially fatal severe adverse to medications. Numerous drugs have been implicated, carbamazepine allopurinol being the most common. Tenofovir-induced DRESS extremely rare. We report case of 65-year-old male patient diffuse exfoliative maculopapular rash across his entire body five weeks duration. The also had icteric sclera, abnormal liver enzymes Raynaud’s tongue, nose left fifth finger. After discontinuation...
West Virginia has the highest incidence of obesity, smoking, and diabetes within United States, placing its population at higher risk stroke. In addition to these endemic factors, Appalachia faces various socioeconomic health care access challenges that could negatively impact stroke outcomes. At present, there are limited data regarding geographic variables on outcomes in rural Appalachia. We set out quantify Appalachian patterns outcomes.This is a retrospective analysis all patients...
Author BlockFrank H Annie, PhD1, Mark C Bates, MD2, Aravinda Nanjundappa,MD2, Ali Farooq, Elise Anderson, Megan Wood, DNP21CAMC Health Education and Research Institute3200 MacCorkle Ave. SE, Charleston, WV 25304.2CAMC Vascular Center of Excellence, Charleston Area Medical Center.3200 Ave 25304
Marciano Lee1, Elise Anderson1, Ali Farooq1, Mohammed Yasin1, Yazan Alkawaleet1, Frank Annie2Charleston Area Medical Center, Department of Cardiology, 3200 MacCorkle Ave. SE,Charleston, WV 25304CAMC Health Education and Research Institute, 25304Corresponding:Frank Annie MA; MPA; PhDResearch Scientist (Department Cardiology)CAMC Institute3200 25304Cell 304 -395 – 3830Phone 304-388-9921Fax: 304-388-9921Email: Frank.H.Annie@camc.orgKeywords:COVID-19, GEMFIBROZIL, IMMUNE MODULATING...
Marciano Lee1, Elise Anderson1, Ali Farooq1, Mohammed Yasin1, Yazan Alkawaleet1, Frank Annie2Charleston Area Medical Center, Department of Cardiology, 3200 MacCorkle Ave. SE,Charleston, WV 25304CAMC Health Education and Research Institute, 25304Corresponding:Frank Annie MA; MPA; PhDResearch Scientist (Department Cardiology)CAMC Institute3200 25304Cell 304 -395 – 3830Phone 304-388-9921Fax: 304-388-9921Email: Frank.H.Annie@camc.orgKeywords:COVID-19, GEMFIBROZIL, IMMUNE MODULATING...