About
Contact & Profiles
A5102498207
Research Areas
- Analytical Chemistry and Chromatography
- Molecular Sensors and Ion Detection
- Mass Spectrometry Techniques and Applications
King's College London
2022
Bacteria can resist antibiotics and toxic substances within demanding ecological settings, such as low oxygen, extreme acid, during nutrient starvation. MdtEF, a proton motive force-driven efflux pump from the resistance-nodulation-cell division (RND) superfamily, is upregulated in these conditions but its molecular mechanism unknown. Here, we report cryo-electron microscopy structures of Escherichia coli multidrug transporter MdtF native-lipid nanodiscs, including single-point mutant with...
10.1101/2025.04.04.646765
preprint
EN
cc-by
bioRxiv (Cold Spring Harbor Laboratory)
2025-04-04
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