A5090330487- Testicular diseases and treatments
- Mass Spectrometry Techniques and Applications
- Prostate Cancer Treatment and Research
- Sarcoma Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Glioma Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Urologic and reproductive health conditions
- Hormonal and reproductive studies
- Radiopharmaceutical Chemistry and Applications
- Cancer Genomics and Diagnostics
- Polyomavirus and related diseases
- Bone health and treatments
- Advanced Proteomics Techniques and Applications
- Brain Metastases and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Analytical Chemistry and Chromatography
- Colorectal Cancer Treatments and Studies
- Melanoma and MAPK Pathways
- Ferroptosis and cancer prognosis
- Lung Cancer Research Studies
- Renal cell carcinoma treatment
- Cancer and Skin Lesions
- Nonmelanoma Skin Cancer Studies
Gosford Hospital
2019-2021
Royal North Shore Hospital
2017-2020
Macquarie University
2019-2020
Cancer Australia
2020
Westmead Hospital
2018-2019
Sydney Adventist Hospital
2017
Abstract Paper spray ionization (PSI) is a direct, fast, and low‐cost ambient technique which may have clinical utility for qualitative quantitative analysis of therapeutic drugs metabolites from patient specimens. We developed validated PSI‐mass spectrometry (PSI‐MS/MS) method according to the US‐FDA guidelines bioanalytical studies measure prostate cancer drug abiraterone directly plasma. The established linearity range was 3.1–156.8 ng/mL with precision (%CV) an accuracy (%) 0.5–10.7...
Abstract Background There are few studies examining retroperitoneal lymph node dissection (RPLND) for testicular cancer in Australia. This study examines the perioperative outcomes, complications and survival rates following RPLND, by a high volume, single surgeon. Methods A retrospective, case series of surgeon, multi‐centre included all patients who underwent RPLND at Westmead Public Hospital, Private Macquarie University Hospital 2005–2020. One hundred one identified, with 94 having...
Cabazitaxel prolongs survival in patients with metastatic castration-resistant prostate cancer the postdocetaxel setting. We investigate benefit of continuing cabazitaxel beyond 10 cycles who are clinically responding without significant toxicity.A comparison was made between received for >10 and those had ≤10 cycles. Overall (OS), prostate-specific antigen (PSA) response, alkaline phosphatase (ALP) changes treatment-associated adverse events were evaluated.The median OS 9 months (range...
To evaluate disease presentation, treatment practices, and outcomes of patients with germ cell tumor (GCT) treated in a high-volume cancer center Australia.This is retrospective analysis 609 diagnosed GCT the Sydney West Cancer Network between 1990 2013. Cause date death, second malignancy information was sourced from The Centre for Health Record Linkage.The median age 33 years (range, 14-85). Primary site testis 590 (96.9%), mediastinum nine (1.5%), retroperitoneum (1.5%). History...
e16534 Background: GCT accounts for 1-2% of all malignancies and are the most common invasive cancer in men aged between 15 to 34 years. Treatment is associated with high cure rate, but at cost long term morbidity. We analysed patients treated a high-volume centre Australia evaluate disease presentation, treatment practices outcome. Methods: This retrospective analysis 611 diagnosed Sydney West Cancer Network 1990 2013. Data collected includes demographics, risk factors, characteristics,...
e21225 Background: Despite improvements in survival with treatment using single agent Programmed Cell Death Protein-1 inhibitors (PD1i) second and subsequent line setting for metastatic NSCLC, a significant proportion of patients(pts), even when selected based on PD-L1 expression, do not respond. We investigated the impact rate disease progression(ROP) prior to commencement PD1i efficacy PD1i. Methods: Retrospective data pts who have failed systemic therapy, treated either nivolumab or...