A5050507297- Synthesis and properties of polymers
- Silicone and Siloxane Chemistry
- Inorganic and Organometallic Chemistry
- Mass Spectrometry Techniques and Applications
- Prostate Cancer Treatment and Research
- Epoxy Resin Curing Processes
- Hormonal and reproductive studies
- Synthetic Organic Chemistry Methods
- Extraction and Separation Processes
- Photopolymerization techniques and applications
- Electrochemical Analysis and Applications
- Carbon dioxide utilization in catalysis
- Soil and Unsaturated Flow
- Alzheimer's disease research and treatments
- Advanced Polymer Synthesis and Characterization
- Rheology and Fluid Dynamics Studies
- Circular RNAs in diseases
- Kawasaki Disease and Coronary Complications
- Catalytic Cross-Coupling Reactions
- Material Properties and Applications
- COVID-19 Impact on Reproduction
- Intracerebral and Subarachnoid Hemorrhage Research
- Phosphorus compounds and reactions
- Polymer Science and Applications
- Amyotrophic Lateral Sclerosis Research
The University of Sydney
2024
Australian Genome Research Facility
2020-2022
Tata Steel (India)
2020-2021
Macquarie University
2018-2020
QIMR Berghofer Medical Research Institute
2013
Griffith University
2013
Translational Research Institute
2013
Princess Alexandra Hospital
2013
The University of Queensland
2013
Virginia Tech
1996-2000
Although microRNAs (miRNA) show potential as diagnostic biomarkers in cancer, their role circulating cell-free disease response remains unknown. Candidate miRNA for classical Hodgkin lymphoma (cHL) might arise from Hodgkin-Reed-Sternberg (HRS) cells and/or nonmalignant tumor-infiltrating cells. HRS are sparse within the diseased node, embedded a benign microenvironment, composition of which is distinct that seen healthy lymph nodes.Microarray profiling more than 1,000 human miRNAs 14 cHL...
Abstract Background Hepatocellular carcinoma (HCC) remains a leading life-threatening health challenge worldwide, with pressing needs for novel therapeutic strategies. Sphingosine kinase 1 (SphK1), well-established pro-cancer enzyme, is aberrantly overexpressed in multitude of malignancies, including HCC. Our previous research has shown that genetic ablation Sphk1 mitigates HCC progression mice. Therefore, the development PF-543, highly selective SphK1 inhibitor, opens new avenue treatment....
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that currently has no cure. Identifying biochemical changes associated with neurodegeneration prior to symptom onset, will provide insight into the biological mechanisms processes, may also aid in identifying potential drug targets. The current study therefore investigated associations between plasma neurofilament light chain (NF-L), marker of neurodegeneration, metabolites are products various cellular processes. Plasma...
Abstract COVID-19 has infected more than 275 million worldwide (at the beginning of 2022). Children appear less susceptible to and present with milder symptoms. Cases children developing clinical features Kawasaki-disease have been described. Here we utilise Mass Spectrometry proteomics determine plasma proteins expressed in healthy pre-pandemic, multisystem inflammatory syndrome (MIS-C) induced ARDS. Pathway analyses were performed affected pathways. 76 are differentially across groups, 85...
Raman and infrared spectra of a bisphenol-A-containing azoaromatic polyether, azoxyaromatic polyether 2-hydroxyazoaromatic were analyzed. Vibrational also collected for the corresponding model compounds 4,4′-(4-tert-butylphenoxy)azobenzene, 4,4′-(4-tert-butylphenoxy)azoxybenzene 4,4′-(4-tert-butylphenoxy)-2-hydroxyazobenzene. Comparisons with substituted azobenzenes azoxybenzenes used in assigning 1650–900 cm-1 region. Assignments N=N stretch (1410–1390 cm-1) demonstrate that all are trans...
Abstract Paper spray ionization (PSI) is a direct, fast, and low‐cost ambient technique which may have clinical utility for qualitative quantitative analysis of therapeutic drugs metabolites from patient specimens. We developed validated PSI‐mass spectrometry (PSI‐MS/MS) method according to the US‐FDA guidelines bioanalytical studies measure prostate cancer drug abiraterone directly plasma. The established linearity range was 3.1–156.8 ng/mL with precision (%CV) an accuracy (%) 0.5–10.7...
Background: Cerebral amyloid angiopathy (CAA) is one of the major causes intracerebral hemorrhage and vascular dementia in older adults. Early diagnosis will provide clinicians with an opportunity to intervene early suitable strategies, highlighting importance pre-symptomatic CAA biomarkers. Objective: Investigation related blood metabolite alterations Dutch-type hereditary mutation carriers (D-CAA MCs). Methods: Plasma metabolites were measured using mass-spectrometry (AbsoluteIDQ® p400 HR...
A series of amorphous and semicrystalline poly(aryl ether–bisketone)s have been synthesized from bisphenols 4,4′-bis(p-fluorobenzoyl)biphenyl via nucleophilic aromatic substitution reactions. Model compound studies were carried out with a variety substituted phenols. 4,4′-bis(p-chlorobenzoyl)biphenyl. The bishalide monomers by the reaction biphenyl-4,4′-dicarboxylic acid thionyl chloride followed Friedel–Crafts acylation appropriate aryl halide. Potassium carbonate mediated these in...
Abstract Twenty-one laboratories participated in a collaborative study to validate hydrophobic grid membrane filter (HGMF) method for aerobic plate count by comparing its performance against the AOAC/APHA pour method. Raw milk, raw poultry, whole egg powder, flours, and spices were included study. Counts obtained HGMF methods did not differ significantly, except case of which produced significantly higher counts. The foods has been adopted official first action.
Abstract The effects of N ‐methyl‐2‐pyrrolidinone (NMP) as solvent on the polymerization reactions 1,3‐bis(4‐chlorobenzoyl)benzene (1,3‐CBB) and 1,3‐bis(4‐fluorobenzoyl)benzene (1,3‐FBB) with 4,4′‐isopropylidenediphenol (bisphenol‐A) were examined. failure these to produce high molecular weight polymers in presence anhydrous potassium carbonate is due dehalogenation 1,3‐CBB via substitution radical‐nucleophilic unimolecular (S RN 1 ) processes. On other hand, 1,3‐FBB undergoes nucleophilic...
Abstract A series of controlled molecular weight poly(aryl ether sulfone) oligomers with benzophenone moieties at the chain termini were prepared. The two carbonyl groups ends converted to ethynyl by using trimethylsilyldiazomethane/BuLi in tetrahydrofuran. Reactions 4,4′‐isopropylidenediphenol 4,4′‐difluorobenzophenone and 4‐fluorophenylphenylacetylene as end‐capping reagent N , ‐dimelthylacetamide afforded desired ketone) Both sulfone ketone containing oligomeric polyethers undergo...
Abstract The 1H and 13C NMR spectra of three aromatic ketimines with varying degrees fluoro substitution have been extensively studied using one two dimensional techniques. COSY experiments were conducted to identify the protons on each groups, HETCORR then utilized corresponding carbon atoms, order atoms was established by long-range (HRTCORRLR) results. These studies allowed rigorous assignments be made for most hydrogen present in these compounds. Fluorine splittings very helpful...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLigand-accelerated coupled transport of metals across a liquid membrane containing general complexing agentJames A. Cox and Atul. BhatnagarCite this: Anal. Chem. 1988, 60, 10, 986–988Publication Date (Print):May 15, 1988Publication History Published online1 May 2002Published inissue 15 1988https://pubs.acs.org/doi/10.1021/ac00161a009https://doi.org/10.1021/ac00161a009research-articleACS PublicationsRequest reuse permissionsArticle...
Abstract AsI3 is demonstrated to partition from a 9 M HC1, 0.10 KI, H ascorbic acid solution into kerosene and dodecane membranes which do not contain complexing agents. Subsequent hydrolysis at the membrane receiver interface causes transport of As against its concentration gradient. A 60 minute experiment with 4 mL 200 sample permits preconcentration by factor 16 ± 0.5. The interferences aluminum phosphate on graphite furnace atomic absorption spectro-metric determination are eliminated....