Lan Li

ORCID: 0000-0003-1255-5102
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About
Contact & Profiles
Research Areas
  • Radiomics and Machine Learning in Medical Imaging
  • MRI in cancer diagnosis
  • Ovarian cancer diagnosis and treatment
  • AI in cancer detection
  • Sperm and Testicular Function
  • Muscle activation and electromyography studies
  • Endometrial and Cervical Cancer Treatments
  • Ovarian function and disorders
  • Motor Control and Adaptation
  • Selenium in Biological Systems
  • Pediatric Urology and Nephrology Studies
  • Reproductive Biology and Fertility
  • EEG and Brain-Computer Interfaces
  • Rangeland and Wildlife Management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cerebrovascular and Carotid Artery Diseases
  • Renal cell carcinoma treatment
  • Intracranial Aneurysms: Treatment and Complications
  • Advanced Glycation End Products research
  • Metabolism, Diabetes, and Cancer
  • Ecology and Vegetation Dynamics Studies
  • Mycotoxins in Agriculture and Food
  • Ferroptosis and cancer prognosis
  • Thyroid Cancer Diagnosis and Treatment
  • Ultrasound and Hyperthermia Applications

Affiliated Hospital of North Sichuan Medical College
2024-2025

University of Chicago
2008-2025

Qingdao Agricultural University
2019-2025

Vitebsk State University named after P.M. Masherov
2025

Wenzhou Medical University
2017-2024

First Affiliated Hospital of Wenzhou Medical University
2017-2024

Peking University
2024

Kunming Medical University
2022-2024

Peking University Cancer Hospital
2024

Institute of Grassland Research
2023

This study investigates the effect of dietary Lactobacillus plantarum supplementation on juvenile coho salmon (Oncorhynchus kisutch). Four groups juveniles (initial weight 103.87 ± 2.65 g) were fed for 10 weeks with four diets containing 0 (control diet), 105 (T1), 107 (T2), and 109 (T3) cfu/g L. plantarum. The main results are as follows: Compared control diet, final weight, specific growth rate (SGR), gain (WGR) T1, T2, T3 diet significantly (p < 0.05) increased, while feed coefficient...

10.3390/ijms26030907 article EN International Journal of Molecular Sciences 2025-01-22

Background: Ovarian cancer is the most lethal gynecological malignancy, and chemotherapy remains cornerstone for ovarian management. Due to unsatisfactory prognosis, a better understanding of underlying molecular carcinogenesis urgently required. Methods: Assays determining cell growth, motility, apoptosis were employed evaluate potential antitumor effects metformin against cells. Molecular biological methods explore mechanism. Human samples Gene Expression Profiling Interactive Analysis...

10.1177/09636897211027819 article EN cc-by-nc Cell Transplantation 2021-01-01

The Sustainable Development Goals (SDGs) call for systematic monitoring to optimize child development outcomes. As a developmental disorder affecting children and adults, Autism Spectrum Disorder (ASD) not only impacts individual social functioning but also places burden on families society. A detailed analysis of the latest global data ASD can assist stakeholders in formulating support policies interventions, thereby helping meet health needs ASD. We used from Global Burden Disease Study...

10.3389/fpsyt.2025.1570276 article EN cc-by Frontiers in Psychiatry 2025-04-25

To study value of one-on-one midwifery and music therapy combined program for natural childbirth. This retrospective analyzed the medical records 82 women who gave birth spontaneously in our hospital between January 2020 February 2022. They were grouped based on nursing programs. The control group received routine care, while one-to-one with therapy. Maternal infant outcomes, pelvic floor muscle function, progress labor, neonatal health compared two groups, degree pain anxiety during...

10.1080/14767058.2025.2495685 article EN cc-by The Journal of Maternal-Fetal & Neonatal Medicine 2025-05-15

Background: Ultrasound (US)-guided fine needle aspiration (FNA) cytology is the gold standard for evaluation of thyroid nodules. However, up to 30% FNA results are indeterminate, requiring further testing. In this study, we present a machine-learning analysis indeterminate nodules on ultrasound with aim improve cancer diagnosis. Methods: images were collected from two institutions and labeled according their (F) surgical pathology (S) diagnoses [malignant (M), benign (B), (I)]. Subgroup...

10.1117/1.jmi.9.3.034501 article EN Journal of Medical Imaging 2022-05-26

Background There is a close relationship between radiotherapy and autophagy in tumors, but the prognostic role of radiotherapy-related genes (RRAGs) lung adenocarcinoma (LUAD) remains unclear. Methods Data used current study were extracted from The Cancer Genome Atlas (TCGA) Gene Expression Omnibus (GEO) databases. Weighted gene co-expression network analysis (WGCNA) was executed to recognize module associated with radiotherapy. differentially expressed (DEGs) different response groups...

10.3389/fimmu.2022.992626 article EN cc-by Frontiers in Immunology 2022-10-13

Abstract To investigate the factors that influence readmissions in patients with acute non-ST elevation myocardial infarction (NSTEMI) after percutaneous coronary intervention (PCI) by using multiple machine learning (ML) methods to establish a predictive model. In this study, 1576 NSTEMI who were hospitalized at Affiliated Hospital of North Sichuan Medical College selected as research subjects. They divided into two groups: readmitted group and non-readmitted group. The division was based...

10.1038/s41598-024-64048-x article EN cc-by Scientific Reports 2024-06-11

To address the issues of manual inspection and low precision in detection recognition defects existing animal leather, this study first establishes a leather image dataset applies an improved Gabor filtering algorithm for preprocessing. Specifically, weighted average method is adopted to grayscale image, parameters are designed ensure that most key texture information images obtained, meeting requirements feature subsequent extraction. Next, it explores statistical extraction algorithms...

10.3390/pr13051298 article EN Processes 2025-04-24

Abstract It is generally believed that long-duration gamma-ray bursts (GRBs) originate from the core collapse of rapidly spinning massive stars, and at least some them are powered by hyperaccreting black holes (BHs). However, definite proofs about progenitor central engine these GRBs have not been directly observed in past. Here, we report existence a quasiperiodic oscillation (QPO) signature with periodic frequency ∼0.02 Hz early X-ray afterglow phase GRB 220711B. Such low-frequency QPO...

10.3847/1538-4357/adc4e2 article EN cc-by The Astrophysical Journal 2025-05-13

The timing, intensity and duration of the cytokine cascade reorganized interrelations in networks are not fully understood during acute HIV-1 infection (AHI). Using sequential plasma samples collected over three years post-infection a cohort MSM seroconvertors, we determined early kinetics levels FiebigI-IV stages using Luminex-based multiplex assays. Cytokines were quantified relationships between cytokines assessed by Spearman correlation. Compared with HIV-negative MSM, HIV-infected...

10.1038/srep36234 article EN cc-by Scientific Reports 2016-11-10

Linezolid combination therapy is recommended for the treatment of Staphylococcus aureus (S. aureus) infections. However, optimal regimen S. unknown. The objective this study was to investigate antibacterial activity, post-antibiotic effect (PAE), and subminimum inhibitory concentration (MIC) (PA-SME) linezolid alone in with fosfomycin against eleven clinical isolates aureus.The synergistic effects activity were assessed by checkerboard time-kill assays. To determine PAE PA-SME, strains...

10.2147/idr.s175978 article EN cc-by-nc Infection and Drug Resistance 2018-10-31

Ovarian cancer is one of the most common causes death in gynecological tumors, and its type epithelial ovarian (EOC). This study aimed to establish a radiomics signature based on ultrasound images predict histopathological types EOC.Overall, 265 patients with EOC who underwent preoperative ultrasonography surgery were eligible. They randomly sorted into two cohorts (training cohort: test cohort = 7:3). We outlined region interest tumor lesion. Then, features extracted. Clinical, Rad-score...

10.1259/bjr.20211332 article EN British Journal of Radiology 2022-05-25

The identification of women at risk for sporadic breast cancer remains a clinical challenge. We hypothesize that the temporal analysis annual screening mammograms, using long short-term memory (LSTM) network, could accurately identify future cancer. Women with an imaging abnormality, which had been biopsy-confirmed to be or benign, who also antecedent available were included in this case–control study. Sequences mammograms retrospectively collected under HIPAA-approved guidelines. Radiomic...

10.3390/cancers15072141 article EN Cancers 2023-04-04

Basic fibroblast growth factor (bFGF) has shown great therapeutic effects for diabetic nephropathy (DN). However, its clinical applications are limited due to short half-life, low stability and poor penetration. Herein, a bFGF-loaded liposome (bFGF-lip) was constructed combined with ultrasound-targeted microbubble destruction (UTMD) overcome these drawbacks. bFGF-lip exhibited spherical morphology diameter of 171.1 ± 14.2 nm negative zeta potential -5.15 2.08 mV, exhibiting sustained-release...

10.1080/21691401.2018.1457538 article EN Artificial Cells Nanomedicine and Biotechnology 2018-04-13

Background Aneurysmal subarachnoid haemorrhage (SAH) is a devastating disease. Anterior communicating artery (ACoA) aneurysm the most frequent location of intracranial aneurysms. The purpose this study was to predict clinical outcome at discharge after rupture ACoA using random forest machine learning technique. Methods A total 607 patients with ruptured aneurysms were included in between December 2007 and January 2016. In addition basic variables, 12 morphologic parameters evaluated....

10.3389/fneur.2020.538052 article EN cc-by Frontiers in Neurology 2020-10-29
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