A5101498736- Phytochemicals and Antioxidant Activities
- Drug-Induced Hepatotoxicity and Protection
- Essential Oils and Antimicrobial Activity
- Genomics, phytochemicals, and oxidative stress
- Pharmacological Effects of Natural Compounds
- Natural Antidiabetic Agents Studies
- Berberine and alkaloids research
- Chromatography in Natural Products
- Plant pathogens and resistance mechanisms
- CAR-T cell therapy research
- Hernia repair and management
- Cell Adhesion Molecules Research
- Natural product bioactivities and synthesis
- Radiopharmaceutical Chemistry and Applications
- Breast Lesions and Carcinomas
- Cancer-related molecular mechanisms research
- Sarcoma Diagnosis and Treatment
- Liver Disease and Transplantation
- Stress Responses and Cortisol
- Phytoestrogen effects and research
- Higher Education and Teaching Methods
- Cancer Immunotherapy and Biomarkers
- Uterine Myomas and Treatments
- Phytochemistry and Biological Activities
- Cancer, Lipids, and Metabolism
Henan Provincial People's Hospital
2025
Anhui Medical University
2025
Sichuan University
2024
Tongji Hospital
2023
Huazhong University of Science and Technology
2023
Henan Institute of Technology
2022
China Agricultural University
2021
Ruijin Hospital
2021
Wuhan University
2013-2020
State Council of the People's Republic of China
2016-2018
This work studied the antifungal mechanism of dill seed essential oil (DSEO) against Candida albicans. Flow cytometric analysis and inhibition ergosterol synthesis were performed to clarify action DSEO on C. Upon treatment cells with DSEO, propidium iodide penetrated albicans through a lesion in its plasma membrane. also significantly reduced amount ergosterol. These findings indicate that membrane was damaged by DSEO. The effect functions mitochondria studied. We assayed mitochondrial...
Objective: The study aimed to apply an artificial intelligence (AI)-assisted scoring system, and improve the diagnostic efficiency of Sclerosing adenosis early breast cancer. Methods: This retrospectively collected adenopathy patients (156 cases) cancer (150 in Henan Provincial People's Hospital from August 2020 April 2023. Results: area under curve model constructed by clinical ultrasound features combined AI predict identify two training group was 0.89 0.94, respectively. with best...
This study aimed to evaluate the inhibitory effects of dill (Anethum graveolens L.) seed essential oil against Sclerotinia sclerotiorum and its mechanism action. The antifungal activities two main constituents, namely carvone limonene, were also measured. Mycelial growth sclerotial germination thoroughly inhibited by at 1.00 μL/mL under contact condition 0.125μL/mL air vapor condition. Carvone contributed more than limonene in inhibiting S. sclerotiorum. synergistically fungus. In vivo...
Abstract Background The real-world vaccine effectiveness (VE) of the diphtheria, tetanus, and acellular pertussis (DTaP), DTaP–Haemophilus influenzae type b (Hib), DTaP–inactivated polio (IPV)/Hib vaccines has not been thoroughly evaluated in China. Additionally, there are limited data on VE pertussis–containing (aPVs) when used interchangeably. Methods We conducted a matched case-control study to estimate aPVs against polymerase chain reaction–confirmed infection Lu’an 2024. A conditional...
Cyclophosphamide (CP) is a widely utilized chemotherapy drug.
To systematically study the chemical constituents in Magnolia officinalis var. biloba fruits, nine phenylethanoid glycosides were isolated by solvent extraction, silica gel, and preparative high-performance liquid chromatography (HPLC). Their structures elucidated 1D 2D NMR analyses, including COSY, HMQC HMBC correlations, HPLC analysis of sugar residue. Nine glycosides, namely, magnoloside Ia (1), Ic (2), crassifolioside (3), Ib (4), IIIa (5), IVa (6), IIa (7), IIb (8) Va (9), first from...
Coptis chinensis inflorescence is traditionally used as tea and has been popular in the local market. C. extract (CE) exhibits protective effects against carbon tetrachloride (CCl4)-induced damage, but underlying mechanism remains unclear. The main chemicals of CE were detected, purified, identified this study. linarin could reverse changes cell viability, decrease alanine aminotransferase aspartate transaminase levels, reduce reactive oxygen species (ROS) generation induced by CCl4 HepG2...
Chicory has a major geographical presence in Europe and Asia. Cichorium glandulosum Boiss. et Huet, genus Cichorium, is used for medicinal food purposes In this study, dicaffeoylquinic acid-enriched fraction of C. seeds n-BuOH (CGSB) could ameliorate type 1 diabetes mellitus (T1DM) streptozotocin (STZ)-induced diabetic mice with continuous administration 2 weeks. CGSB treatment showed significantly higher plasma insulin levels but lower free fatty acids adipose tissue liver. Moreover,...
Because of complicated geometric structure C-section rings and the obvious difference volume distribution along axial direction, metal is difficult to flow radial direction fill profile section during ring rolling process. With a typical Inconel718 alloy as research object, blank design method was proposed for redistribute direction. Then based on verified 3D coupled thermo-mechanical FE model, response surface methodology (RSM) employed establish model with high fitting accuracy 98.31%...
Long noncoding RNA (lncRNA) family with sequence similarity 201-member A (FAM201A) is a novel lncRNA promoting the development of various cancers. However, biological function FAM201A on metastasis lung squamous cell carcinoma (LSCC) remains unknown. The aim this study was to explore molecular mechanism and its target protein in advanced LSCC.Quantitative Polymerase Chain Reaction (qPCR) applied evaluate expression cancer tissues. impact high overall survival patients tested using log-rank...
<italic>Chaenomeles thibetica</italic> extract possesses antioxidant and hepatoprotective effects against carbon tetrachloride-induced damage <italic>via</italic> the MAPK/Nrf2 pathway.
Yigan mingmu oral liquid (YGMM) is a herbal medicine based on famous Chinese formula that has been used for sore eyes more than 400 years. Eye health closely associated with the liver TCM. This study aimed to investigate hepatoprotective effect of YGMM against acute injury induced by alcohol in rats.Experimental rats were administered silymarin and through gastric gavage during entire experiment. Starting from 11th day, orally 14 ml/kg Red Star Erguotou Liquor, popular brand, at 4 h after...
Terminalia bellirica (Gaertn.) Roxb. fruit (TBF) is a widely planted traditional medicinal herb in Tibet. We aimed to determine the most active substance-enriched extract by comparing vitro antioxidant activities of different fractions TBF that were subsequently extracted petroleum ether, chloroform, ethyl acetate, and n-butanol after initial extraction 95% ethanol. The main compounds acetate fraction (EF) analyzed via HPLC-MS. Gallic acid (GA) was obtained from EF antifibrotic activity...
Cichorium glandulosum Boiss. et Huet, a common herb for treating hepatitis, is indigenous to Europe, Western Asia, and the Xinjiang Uygur Autonomous Region of China. This study aims at evaluating protective activity different extracts from C. seeds against experimental oxidation- ultraviolet B (UVB)-induced damage in rat liver mitochondria. The antioxidant property was investigated by employing various established vitro systems, such as α,α-diphenyl-β-picrylhydrazyl,...