A5033888482- Pesticide Exposure and Toxicity
- Nanoparticles: synthesis and applications
- PI3K/AKT/mTOR signaling in cancer
- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Telomeres, Telomerase, and Senescence
- Effects and risks of endocrine disrupting chemicals
- Toxic Organic Pollutants Impact
- Exercise and Physiological Responses
- Coenzyme Q10 studies and effects
- Parkinson's Disease Mechanisms and Treatments
- Selenium in Biological Systems
- Sulfur Compounds in Biology
- Hydrogels: synthesis, properties, applications
- Autophagy in Disease and Therapy
- Saffron Plant Research Studies
- Advanced Fluorescence Microscopy Techniques
- Bioactive natural compounds
- RNA Research and Splicing
- Periodontal Regeneration and Treatments
- 3D Printing in Biomedical Research
- Obstructive Sleep Apnea Research
- Multiple Sclerosis Research Studies
- Axon Guidance and Neuronal Signaling
- Autopsy Techniques and Outcomes
Istanbul University
2015-2024
Diabetic peripheral neuropathy has been extensively studied and reported, but the number of studies that have investigated diabetes-related changes in central nervous system are limited, with even fewer on cerebellum. The aim this experimental study was to perform a histologic analysis cerebellums diabetic rats.Twenty Sprague Dawley rats weighing between 200 220 g were included study. Diabetes induced 14 these by single intraperitoneal injection 65 mg/kg streptozotocin dissolved saline,...
Anabolic androgenic steroids (AAS) are performance-enhancing drugs commonly abused by atheletes. Stanozolol is a synthetic testosterone-derived anabolic steroid. Although it well known that AAS have several side-effects, there only few toxicological studies available on the toxic effects and mechanisms of action stanozolol. The aim this study was to investigate genotoxic stanozolol determine its telomerase activity in Sprague-Dawley male rats. For purpose, 34 rats were divided into 5 groups...
Purpose This study aimed to investigate the protective or therapeutic effect of thymoquinone (TQ) in a retinal degeneration rat model and its relationships with retina ultrastructure, heme oxygenase 1 (HO-1), caspase-3, RPE65 expressions determine whether TQ has at biochemical level.
Anabolic agents are doping substances which commonly used in sports. Stanozolol, a 17α‑alkylated derivative of testosterone, has widespread use among athletes and bodybuilders. Several medical behavioral adverse effects associated with anabolic androgenic steroids (AAS) abuse, while the liver remains most well recognized target organ. In present study, hepatic stanozolol administration rats at high doses resembling those for purposes were investigated, presence or absence exercise....
Summary Digyny, the presence of a third pronucleus due to failure second polar body extrusion, is problematic after intracytoplasmic sperm injection (ICSI) practices. Mitochondria have critical roles such as production adenosine triphosphate (ATP) and regulation Ca 2+ homeostasis during oocyte maturation, fertilization following development, while meiotic spindle formation, chromosome segregation, pronuclear apposition cytokinesis closely associated with cytoskeleton. In this study,...
Hydrogen sulfide (H2S) and other volatile sulfur compounds (VSCs) appear mainly in the oral air of patients with halitosis. It seems that VSCs are directly involved pathogenesis gingival diseases. In previous studies, short-term (7 hours–4 days), high concentrations (5–400 ppm) H2S applications on periodontal tissues have been evaluated a culture medium. The aim present study was to investigate potential effects lower (equivalent halitosis) rat tissue for longer-term inhalation. threshold...
To evaluate the origin and ultrastructure of coarse granules in perivitelline space (PVS) oocytes a group couples attending assisted reproduction treatment.The five with granulues PVS obtained from three patients were evaluated by transmission electron microscopy (TEM). The influence ovulation induction regimen on formation 214 developmental capacity these presenting was analyzed retrospectively.In TEM analysis, microvilli structure irregular, short, loosely scattered through oolemma PVS....
Titanium dioxide (TiO2) is one of the most widely used nanoparticles, and aquatic organisms are especially exposed to it. To examine reproductive toxicology, zebrafish were different concentrations (1, 2 4 mg/L) TiO2 nanoparticles. The ultrastructure theca cell, zona radiata structure follicular epithelium examined in detail by transmission electron microscopy (TEM). No abnormalities observed control group; however, degeneration pore microvilli structures radiata, vacuolization ooplasm,...
<title>Abstract</title> Despite the negative environmental and biologic effects, organophosphates have currently been widely used. We aimed to examine possible effects of diazinon, a type organophosphate, on rat ovarian tissue. Wistar Albino rats were divided into four groups. No treatment was given control, olive oil applied sham group. Experimental groups injected intraperitoneally with 30 60 mg/kg/day respectively. 24 hours later, tissues extracted, preparated, examined via light electron...
Objective: Stanozolol is an anabolic androgenic steroid (AAS) that widely used by teenagers and athletes in bodybuilding, sports, athletics. The potential effects of stanozolol kidney functions have not been defined. In this study we investigated the expression tumor suppressor protein phosphatase tensin homolog (Pten) mRNA levels phosphatidylinositol 4,5-bisphosphate 3 kinase (Pi3k) B (Akt1) signaling pathway rat kidneys treated stanozolol. Material Method: Rats were randomized to 5 groups...
Monobenzyl ether of hydroquinone (MBEH) is a topical depigmentation agent used by vitiligo patients to even the skin tone. We aimed investigate effects MBEH on 3T3 mouse fibroblasts. Fibroblasts were treated with 250 µM, 500 and 750 µM vehicle (EtOH:DMSO) for 24 hours. Cell numbers groups decreased significantly compared control group. TUNEL positive cell rate increased concentration. In electron microscopic examination, showed active cells features, while mitochondrial swelling cristae loss...