A5052145037- Advanced Polymer Synthesis and Characterization
- Hydrogels: synthesis, properties, applications
- Synthesis and properties of polymers
- biodegradable polymer synthesis and properties
- Advanced Drug Delivery Systems
- Photopolymerization techniques and applications
- Thermal and Kinetic Analysis
- Polymer Surface Interaction Studies
- Electrospun Nanofibers in Biomedical Applications
- Nanoparticle-Based Drug Delivery
- Polymer Science and PVC
- Surgical Sutures and Adhesives
- Hemostasis and retained surgical items
- Organometallic Complex Synthesis and Catalysis
- Polymer Nanocomposites and Properties
- Silicone and Siloxane Chemistry
- Wound Healing and Treatments
- Polymer Nanocomposite Synthesis and Irradiation
- Tribology and Wear Analysis
- 3D Printing in Biomedical Research
- Polymer crystallization and properties
- Drug Solubulity and Delivery Systems
- Social Skills and Education
- Lanthanide and Transition Metal Complexes
- Additive Manufacturing and 3D Printing Technologies
University of Havana
2011-2023
University of Shanghai for Science and Technology
2023
Abstract The thermal degradation of poly( N ‐vinyl‐2‐pyrrolidone) (PVP) was studied by dynamic thermogravimetric analysis (TGA) in the range 200–600°C under nitrogen and oxygen atmospheres at various heating rates. apparent activation energy degradative process determined application kinetic treatments, giving an average value 242 kj/mol 2 , whereas presence oxygen, two trends may be considered: At relatively low temperatures (200–400°C) degrees conversion, α, lower than 0.5, we obtained 199...
In this study, Magnetic microspheres formed by Magnetite, Paclitaxel (PCT), poly(lactic acid) (PLA), and poly(ethylene glycol) (PEG) diblock copolymers material, synthesized the Ugi four‐component condensation reaction (UFCC), are prepared single emulsion solvent evaporation procedure. Prepared PCT‐loaded magnetic (PCTMMS) characterized induction hyperthermia (MIH), SEM, LDS techniques. Microencapsulation process yielded PCT encapsulation efficiency (Ee) between 70 80%, determined HPLC...
ABSTRACT Microparticles formed by poly(lactic acid) (PLA) and poly(ethylene glycol) (PEG) diblock copolymers containing fluorescein grafted to the polymer chain were synthesized a Ugi four‐component condensation (UFCC) reaction. To synthesize these copolymers, lactide was first polymerized ring‐opening polymerization with alcohol initiators functional groups give carboxyl‐ aldehyde‐end‐functionalized PLA. Two different fluorescent block (FCPs) of PEG–PLA conjugated (FCP 1 FCP 2) then UFCC;...
pH‐sensitive microparticles formed by combination of a synthetic copolymer and sodium alginate in presence calcium chloride were prepared mild conditions for specific water‐soluble drug delivery. The copolymers acryloxyethyl‐trimethylammonium N ‐vinyl‐2‐pyrrolidone synthesized radical polymerization aqueous solution at 60°C using persulfate as initiator. Fourier transform infrared spectroscopic characterization confirmed the structure their compositions determined potentiometric method....
Abstract Free radical copolymerization of acryloxyethyl–trimethylammonium chloride with 2–hydroxyethyl methacrylate using sodium persulfate as initiator was carried out at 60°C and its electrostatic interaction alginate (NaAlg) allowed obtaining polymeric microparticles by complex coacervation. The solute transport in this swellable matrix investigated to check the effect cross‐linking simulated physiological condition over release process. Cefazolin Sodium loaded were prepared incorporation...
Abstract Copolymers of furfuryl acrylate ( F ) and 2‐hydroxyethyl methacrylate H were prepared by free radical polymerization in DMF solution at 50°C, using 2,2′‐azobisisobutyronitrile (AIBN) as initiator. The reactivity ratios both monomers calculated according to the general copolymerization equation Fineman‐Ross Kelen‐Tüdös linearization methods, well Tidwell Mortimer nonlinear least‐squares treatment. obtained r = 0.93 1.42. microstructure copolymer chains is described on basis...
Abstract Hydrogels are hydrophilic polymers that swell to an equilibrium volume in the presence of water, preserving their shape. The dynamic swelling behavior poly( N ‐isopropylacrylamide‐ co ‐ N,N ‐dimethylacrylamide) [poly(NIPA‐ ‐DMA)] copolymers at 37°C was investigated. It observed degree decreases with ‐isopropylacrylamide content. In addition, liberation mechanism found be Fickian. Diffusion coefficients according Fick′s law as a function concentration and results release process...
Abstract Poly(acryloxyethyl‐trimethylammonium chloride‐ co ‐2‐hydroxyethyl methacrylate) [poly(Q‐ ‐H)] was prepared by free radical polymerization in aqueous solution at 60°C using potassium persulfate as initiator. Spectroscopic characterization confirmed the formation of poly(Q‐ ‐H) and molar fractions acryloxyethyl‐trimethylammonium chloride monomer units incorporated copolymers were determined potenciometric titrations. The reactivity ratios for Q H are found to be r = 0.04 ± 0.01 3.22...
Abstract The thermal behaviour of random copolymers furfuryl methacrylate (F) and N ‐vinylpyrrolidone (P) was studied by means dynamic thermogravimetric analysis (TGA) in the range 100–600°C. experiments show that these exhibit two degradation steps intervals 260–320°C 350–520°C, respectively. normalized weight loss low temperature interval increases as mole fraction F copolymer m increases, whereas an inverted trend high is observed. apparent activation energy E a first step for prepared...
Two different fluorescent block copolymers of poly(lactic acid) (PLA) and polyethylene glycol (PEG) containing fluorescein grafted to the polymer chain were synthesized by Ugi four-component condensation (UFCC). The structure these PEG–PLA was confirmed 1H-NMR fluorescence spectroscopy. Paclitaxel-loaded microspheres (PCT-FMS1 PCT-FMS2) prepared from them single-emulsion solvent evaporation method. A kinetic study drug release in vitro using high-performance liquid chromatography showed a...
Copolymers of 2–hydroxyethyl methacrylate (E) and furfuryl acrylate (A) were prepared by free radical polymerization in toluene at 80°C using benzoyl peroxide as initiator. analyzed 1H–NMR order to calculate the monomer composition copolymer. The reactivity ratios determined four linear methods, Fineman–Röss, r1 = 1.33/r2 0.96; Fineman–Röss inverted, 1.27/r2 0.92; Kelen–Tüdos, 1.3/r2 0.96 Kelen–Tüdos extended, 0.9982/r2 1.0004. Akaike Information Criterion was used select best r1–r2 pair...
Abstract Interpenetrating polymeric networks (IPNs) based on natural sodium alginate (NaAlg) biopolymer matrix and synthetic hydrophilic polymer were synthesized using sequential method. Poly(acryloxyethyl‐trimethylammonium chloride‐ co ‐2‐hydroxyethyl methacrylate) (poly(Q‐ ‐H)) with high content of quaternary ammonium groups (Q units) was used as a for the purpose. Since NaAlg has anionic nature poly(Q‐ ‐H) is polycation polyelectrolyte complex (PEC) also prepared via ion interaction...