A5100709040- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Electrospun Nanofibers in Biomedical Applications
- Nanoparticle-Based Drug Delivery
- Wound Healing and Treatments
- Pancreatitis Pathology and Treatment
- Extracellular vesicles in disease
- Helicobacter pylori-related gastroenterology studies
- Advanced Photocatalysis Techniques
- Hemostasis and retained surgical items
- Graphene and Nanomaterials Applications
- Pancreatic and Hepatic Oncology Research
- Eosinophilic Esophagitis
- Surgical Sutures and Adhesives
- MXene and MAX Phase Materials
- Gastroesophageal reflux and treatments
- Periodontal Regeneration and Treatments
- Abdominal vascular conditions and treatments
- Hydrogels: synthesis, properties, applications
- Advanced Drug Delivery Systems
- Microbial Community Ecology and Physiology
- Gold and Silver Nanoparticles Synthesis and Applications
- Carbon and Quantum Dots Applications
- Gastrointestinal motility and disorders
- Cancer Research and Treatments
Changhai Hospital
2016-2025
Second Military Medical University
2016-2025
Chinese Academy of Sciences
2013-2024
Qinghai New Energy (China)
2024
Dalian University of Technology
2024
Changzhou Academy of Intelli-Ag Equipment (China)
2024
Qingdao Institute of Bioenergy and Bioprocess Technology
2019-2024
Shanghai Institute of Hematology
2019-2024
Zhejiang Sci-Tech University
2024
National Clinical Research Center for Digestive Diseases
2024
The overproduction of reactive oxygen species (ROS) is central to the progression inflammatory bowel disease (IBD), which may be potential therapeutic target. Prussian blue (PB) nanoparticles with good biosafety can act as an artificial nanozyme, effectively scavenging ROS. To date, PB-based nanomaterials have not been developed and utilized for treatment IBD. In this study, poly(vinylpyrrolidone)-modified (PPB) are constructed physiological stability by a simple efficient method. prepared...
The overproduction of reactive oxygen species (ROS) is linked to inflammatory bowel disease (IBD) and causes oxidative damage DNA, proteins, lipids. These ROS promote the initiation progression ulcerative colitis (UC). This study proposes a unique concept nanomaterials with intrinsic enzyme-like activity (nanozymes) mediate catalytic nanotherapy for IBD. Methods: We first synthesized manganese Prussian blue nanozymes (MPBZs) multi-enzyme activity. A dextran sulfate sodium (DSS)-induced mouse...
Abstract In this study, biocompatible Fe(III) species‐WS 2 ‐polyvinylpyrrolidone (Fe(III) @ WS ‐PVP) nanocapsules with enhanced biodegradability and doxorubicin (DOX) loading capacity are one‐pot synthesized. nanocapsule, there exists a redox reaction between species to form Fe 2+ WO 4 2− . The formed could be oxidized 3+ , which reacts ‐PVP again continuously produce Such repeated endogenous leads an biodegradation DOX release of ‐PVP. More strikingly, the generation further accelerated by...
Acute pancreatitis (AP) is a serious acute condition affecting the abdomen and shows high morbidity mortality rates. Its global incidence has increased in recent years. Inflammation oxidative stress are potential therapeutic targets for AP. This study was conducted to investigate intrinsic anti-oxidative anti-inflammatory effects of Prussian blue nanozyme (PBzyme) on AP, along with its underlying mechanism.
In recent years, the incidence of chronic pancreatitis has increased significantly. Pancreatic calculi obstruct pancreatic duct and induce abdominal pain in patients. stenting is major treatment option for with calculi. this study, a new kind drug-eluting stent, stent coated by methacrylated gelatin (GelMA) hydrogel loaded citric acid (CA), was designed interventional The CA loading capacity reached up to 0.7 g CA/g hydrogel-coated stent. GelMA coating higher mechanical strength lower...