- Liver Disease Diagnosis and Treatment
- Computational Drug Discovery Methods
- Biomedical Text Mining and Ontologies
- Drug Transport and Resistance Mechanisms
- Advanced Malware Detection Techniques
- ATP Synthase and ATPases Research
- Cholesterol and Lipid Metabolism
- Peroxisome Proliferator-Activated Receptors
- Health Systems, Economic Evaluations, Quality of Life
- Semantic Web and Ontologies
- Digital and Cyber Forensics
- Carcinogens and Genotoxicity Assessment
- Cholinesterase and Neurodegenerative Diseases
- Hepatitis B Virus Studies
- Bioinformatics and Genomic Networks
- Scientific Computing and Data Management
- Network Security and Intrusion Detection
- Pesticide Exposure and Toxicity
- Clinical Nutrition and Gastroenterology
- Liver physiology and pathology
- Pesticide Residue Analysis and Safety
- Metabolism and Genetic Disorders
- Statistical and Computational Modeling
- Genetics, Bioinformatics, and Biomedical Research
Vrije Universiteit Brussel
2022-2024
Adverse outcome pathway (AOP) networks are versatile tools in toxicology and risk assessment that capture visualize mechanisms driving toxicity originating from various data sources. They share a common structure consisting of set molecular initiating events key events, connected by event relationships, leading to the actual adverse outcome. AOP be considered living documents should frequently updated feeding new data. Such iterative optimization exercises typically done manually, which not...
The evaluation of the potential carcinogenicity is a key consideration in risk assessment chemicals. Predictive toxicology currently switching toward non-animal approaches that rely on mechanistic understanding toxicity.
Abstract Parenteral nutrition (PN) is typically administered to individuals with gastrointestinal dysfunction, a contraindication for enteral feeding, and need nutritional therapy. When PN the only energy source in patients, it defined as total parenteral (TPN). TPN life-saving approach different patient populations, both infants adults. However, despite numerous benefits, can cause adverse effects, including metabolic disorders liver injury. TPN-associated injury, known intestinal...