A5037963837- Acne and Rosacea Treatments and Effects
- Retinoids in leukemia and cellular processes
- Autoimmune Bullous Skin Diseases
- Porphyrin Metabolism and Disorders
- Genetic and rare skin diseases.
- Pharmacological Effects of Natural Compounds
- melanin and skin pigmentation
- Essential Oils and Antimicrobial Activity
- Hedgehog Signaling Pathway Studies
- Neurological diseases and metabolism
- Hair Growth and Disorders
- Dermatology and Skin Diseases
- RNA and protein synthesis mechanisms
- Cancer and Skin Lesions
- DNA Repair Mechanisms
- Vitamin C and Antioxidants Research
- RNA Research and Splicing
- Dermatological and Skeletal Disorders
- Nail Diseases and Treatments
- Cutaneous lymphoproliferative disorders research
- RNA regulation and disease
Nanchang University
2022-2025
Second Affiliated Hospital of Nanchang University
2022-2025
Acne vulgaris (AV), a chronic inflammatory pilosebaceous disorder, affects 80-90% of teenagers. This study aimed to discover lipid profiles and biomarkers the rabbit ear acne model, investigate mechanism isotretinoin in treating at level.
Background: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit. This study aimed to explore pathogenesis acne and therapeutic mechanism isotretinoin from metabolic perspective in coal tar-induced rabbits. Methods: Ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UHPLC-qTOF-MS) based metabolomics was used identify skin metabolites groups C (blank control), M (model group) T (isotretinoin group). Multivariate statistical analysis...
Hailey-Hailey disease (HHD), also known as familial benign chronic pemphigus, is a rare autosomal dominant inherited blistering dermatosis. Pathogenic variants in ATP2C1 have been associated with HHD since 2000. This study aimed to identify the mutations gene two Chinese pedigrees and sporadic cases HHD.Two were included this study. Whole-exome sequencing Sanger performed detect mutation of gene. Predictions protein structure function using bioinformatics tools, including Mutation Taster,...
Dyschromatosis symmetrica hereditaria (DSH) is a rare autosomal dominant inherited pigmentary dermatosis. The gene responsible for DSH has been identified as adenosine deaminase acting on RNA1 (
Purpose: Porokeratosis (PK) is a chronic autosomal-dominant cutaneous keratinization disorder exhibiting clinical and genetic heterogeneity. Mevalonate decarboxylase ( MVD ), farnesyl diphosphate synthase FDPS phosphomevalonate kinase( PMVK mevalonate kinase genes( MVK which encode the pathway, are disease-causing genes in PK. Patients Methods: Data blood samples were collected from two Chinese families five sporadic patients with porokeratosis. Whole-exome Sanger sequencing performed to...
In this letter, we discuss the topic of necessity routine laboratory monitoring during isotretinoin treatment for acne. According to Park and colleagues, it is advisable monitor levels triglycerides, alanine aminotransferase, aspartate aminotransferase every 5 6 months. Additionally, total cholesterol low-density lipoprotein should be checked within first two months treatment. Isotretinoin a commonly prescribed agent mainly used treat Despite its high effectiveness, necessitates regular...
We report a Chinese consanguineous family with variant type of xeroderma pigmentosum (XPV), and identified one novel mutation in the patient. Our study expands mutational spectrum XPV. Click here for corresponding questions to this CME article.