A5036758223- Kruppel-like factors research
- Cell Adhesion Molecules Research
- Platelet Disorders and Treatments
- Chronic Myeloid Leukemia Treatments
- Cardiac Fibrosis and Remodeling
- Congenital heart defects research
Cincinnati Children's Hospital Medical Center
2020-2024
Blood vessels in different vascular beds vary size, which is essential for their function and fluid flow along the network. Molecular mechanisms involved formation of a lumen appropriate or tubulogenesis, are still only partially understood. Src homology 2 domain containing E (She) protein was previously identified screen proteins that interact with Abelson (Abl)-kinase. However, its biological role has remained unknown. Here we demonstrate She Abl signaling regulate vessel size zebrafish...
Abstract Blood vessels in different vascular beds vary lumen diameter, which is essential for their function and fluid flow along the network. Molecular mechanisms involved formation of a appropriate size, or tubulogenesis, are still only partially understood. Src homology 2 domain containing E (She) protein was previously identified screen proteins that interact with Abelson (Abl)-kinase. However, its biological role has remained unknown. Here we demonstrate She Abl signaling regulate size...