A5101691207- Genomics and Phylogenetic Studies
- RNA and protein synthesis mechanisms
- Microgrid Control and Optimization
- Genetic Associations and Epidemiology
- Advanced DC-DC Converters
- Chromosomal and Genetic Variations
- Genomics and Rare Diseases
- Surface Roughness and Optical Measurements
- Tribology and Lubrication Engineering
- 3D Surveying and Cultural Heritage
- Optical measurement and interference techniques
- Multilevel Inverters and Converters
- Evolution and Genetic Dynamics
- Inertial Sensor and Navigation
- Heat Transfer and Optimization
- Genetic diversity and population structure
- Bacteriophages and microbial interactions
- Remote Sensing and LiDAR Applications
- Advanced Measurement and Metrology Techniques
- Gene expression and cancer classification
- Solar Thermal and Photovoltaic Systems
- HVDC Systems and Fault Protection
- Heat Transfer Mechanisms
- Advanced Sensor and Control Systems
- Industrial Technology and Control Systems
Harbin Institute of Technology
2008-2023
Combined Arms Academy of the Armed Forces of the Russian Federation
2010
Pacific Biosciences (PacBio) and Oxford Nanopore Technologies (ONT) sequencing technologies can produce long-reads up to tens of kilobases, but with high error rates. In order reduce error, Rolling Circle Amplification (RCA) has been used improve library preparation by amplifying circularized template molecules. Linear products the RCA contain multiple tandem copies molecule. By integrating additional in silico processing steps, these sequences be collapsed into a consensus sequence higher...
In this paper, the source converter (voltage rectifier) of a cascaded system is modeled based on small signal analysis, and closed-loop transfer functions are obtained. Then, output impedance calculated. The analysis indicates that smaller bus capacitance, worse stability system, power converted by system. Three kinds virtual control methods proposed to reduce converter; all them improve increase maximum parameters three designed their effects compared. Simulation experimental results show...
Circular consensus sequencing reads are promising for the comprehensive detection of structural variants (SVs). However, alignment-based SV calling pipelines computationally intensive due to generation complete read-alignments and its post-processing. Herein, we propose a SKeleton-based analysis toolkit Structural Variation (SKSV). Benchmarks on real simulated datasets demonstrate that SKSV has an order magnitude faster speed than state-of-the-art approaches; moreover, it achieves higher F1...
Abstract Long-read sequencing technologies have great potential for the comprehensive discovery of structural variation (SV). However, accurate genotype assignment SV is still a challenge due to unavoidable factors, such as specific errors or limited coverage. Herein, we propose cuteSV2, fast and long-read-based regenotyping approach that used force calling genotypes given records. In which an upgraded version cuteSV, improved refinement strategy applied on signatures, heuristic extracted...
Abstract Long-read sequencing enables the comprehensive discovery of structural variations (SVs). However, it is still non-trivial to achieve high sensitivity and performance simultaneously due complex SV characteristics implied by noisy long reads. Therefore, we propose cuteSV, a sensitive, fast scalable long-read-based detection approach. cuteSV uses tailored methods collect signatures various types SVs employs clustering-and-refinement method analyze implement sensitive detection....
There is still a lack of fast and accurate classification tools to identify the taxonomies noisy long reads, which bottleneck use promising long-read metagenomic sequencing technologies. Herein, we propose de Bruijn graph-based Sparse Approximate Match Block Analyzer (deSAMBA), tailored approach that uses novel pseudo alignment algorithm based on sparse approximate match block (SAMB). Benchmarks real datasets demonstrate deSAMBA enables achieve high yields speed simultaneously, outperforms...
As an important interface converter, the three-phase voltage-source rectifier (VSR) connects grid to DC-input converters. The constant power load (CPL) characteristic of converter-load often causes large-signal stability problems. In order solve this problem, boundary VSR with CPL is analyzed based on mixed potential theory, and condition under disturbance obtained; thus, jump range can be estimated. To improve system, a voltage loop control scheme ADRC proposed. A theoretical analysis...
Many genetic variants have been reported from sequencing projects due to decreasing experimental costs. Compared the current typical paradigm, read mapping incorporating existing can improve performance of subsequent analysis. However, storing and indexing various types variation require costly RAM space. Aligning reads a graph model-based index including whole set is ultimately an NP-hard problem in theory. This method supposed map efficiently graphical with reference genome known increase...
Abstract The development of long-read sequencing is promising to high-quality and comprehensive de novo assembly for various species around the world. However, it still challenging genome assemblers well-handle thousands genomes, tens gigabase level sizes terabase datasets simultaneously efficiently, which a bottleneck large studies. A major cause read overlapping graph construction that state-of-the-art tools usually have cost terabyte-level RAM space days genomes. Such lower performance...
In order to enhance reliability and maintainability of ship monitoring system, this paper proposed a CANopen protocol-based intelligent sensor which can simultaneously monitor rotational speed temperature. With the presented sensor, data collection control be achieved easily effectively. Experiments were conducted, showed that could simplify make maintenance easier improve greatly.