A5064746245- Epilepsy research and treatment
- Metabolism and Genetic Disorders
- EEG and Brain-Computer Interfaces
- Pharmacological Effects and Toxicity Studies
- ATP Synthase and ATPases Research
- Fetal and Pediatric Neurological Disorders
- Multiple Sclerosis Research Studies
- Genetics and Neurodevelopmental Disorders
- Neonatal and fetal brain pathology
- Language, Metaphor, and Cognition
- Gastroesophageal reflux and treatments
- Neurological disorders and treatments
- Neurological and metabolic disorders
- Pharmaceutical studies and practices
- Advanced Battery Technologies Research
- Health Systems, Economic Evaluations, Quality of Life
- Mental Health and Patient Involvement
- Diet and metabolism studies
- Infectious Encephalopathies and Encephalitis
- Cardiovascular Syncope and Autonomic Disorders
University of Alberta
2021-2025
Stollery Children's Hospital
2022
University of Calgary
2019
Imaging Center
2014
McGill University
2014
Children's Hospital of Philadelphia
2014
Hospital for Sick Children
2014
University of Toronto
2014
Montreal Neurological Institute and Hospital
2014
To determine the impact of pediatric-onset multiple sclerosis (MS) on age-expected brain growth.Whole and regional volumes 36 patients with relapsing-remitting MS onset prior to 18 years age were segmented in 185 longitudinal MRI scans (2-11 per participant, 3-month 2-year scan intervals). 25 age- sex-matched healthy normal controls (NC) also acquired at baseline 2 later same scanner as group. A total 874 from 339 participants NIH-funded study development intervals used an growth reference....
Abstract Stereoelectroencephalography (SEEG) is the preoperative assessment of choice when epileptogenic zone (EZ) unclear in patients requiring surgery for severe, drug-refractory epilepsy. There are relatively little data on safety and efficacy SEEG pediatric epilepsy population. We, therefore, investigated insertional complications, rate successful identification EZ, long-term seizure outcomes following after children. This was a retrospective study drug-resistant treated with between...
Abstract The infantile spasms (IS) syndrome is a developmental epileptic encephalopathy disorder characterized by occurring in infancy, hypsarrhythmia on the electroencephalography (EEG) and arrest or regression. etiologies include structural, metabolic, genetic causes. We report an unusual case of IS due to de novo variant MECP2 gene. patient also had variants uncertain significance SCN9A SCN5A genes inherited from father mother, respectively. This highlights need for broad testing...
Background: Epileptic discharges localized to the midline vertex are rare. However, they have been associated with intractable seizures and severe long-term consequences in developing brain. Our study aimed understand etiology of pediatric define post-surgical seizure outcomes. Methods: We reviewed charts, electroencephalography (EEG), neuroimaging studies ten patients epileptic Comprehensive Epilepsy Program. The were classified according International League Against criteria, patient age,...
Background: Epilepsy, a common neurologic condition, instigates large number of emergency room (ER) visits annually. This project aims to retrospectively review the patterns and characteristics Alberta ER by pediatric epilepsy patients. Methods: Health administrative databases, including Inpatient Discharge Abstract Database, National Ambulatory Care Reporting System, Diagnostic Imaging Medical Laboratory, were used identify utilization among children with in Alberta, Canada between...
Background: We describe an infant with a diagnosis of GM3 synthase deficiency, presenting severe neuroirritability from birth. He required multiple admissions due to extreme agitation and caregiver burnout. Multiple pharmacological agents were tried, the effect each medication was modest short-lasting at best. The literature on management in children progressive genetic metabolic conditions is sparse, protocol has yet be developed our institution. Methods: searched for relevant primary...