A5041198204- Thyroid Cancer Diagnosis and Treatment
- Diabetes Treatment and Management
- Thyroid Disorders and Treatments
- Diabetes Management and Research
- Metabolism, Diabetes, and Cancer
- Thyroid and Parathyroid Surgery
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Anomalies
- Chronic Kidney Disease and Diabetes
- Pituitary Gland Disorders and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diet and metabolism studies
- Medical Imaging Techniques and Applications
- Blood Pressure and Hypertension Studies
- Bone health and osteoporosis research
- Cardiovascular Health and Disease Prevention
- Dialysis and Renal Disease Management
- Parathyroid Disorders and Treatments
- Vitamin D Research Studies
- Liver Disease Diagnosis and Treatment
- BRCA gene mutations in cancer
- Growth Hormone and Insulin-like Growth Factors
- Radiation Dose and Imaging
- Diabetes Management and Education
- Pancreatic function and diabetes
Pusan National University Hospital
2015-2024
Pusan National University
2011-2023
Chung-Ang University
2023
University of Cincinnati
2015-2023
Dong-A University
2023
Biomedical Research Institute
2013-2020
Busan Medical Center
2019
Busan National University of Education
2018
Institute of Neurobiology
2015
GTx (United States)
2013
This study was done to evaluate clinical usefulness of cystatin C levels serum and urine in predicting renal impairment normoalbuminuric patients with type 2 diabetes the association between albuminuria serum/urine C. Type diabetic (n = 332) normoalbuminuria 210), microalbuminuria 83) macroalbuminuria 42) were enrolled. Creatinine, urinary albumin levels, estimated glomerular filtration rate (eGFR by MDRD [Modification Diet Renal Disease] CKD-EPI [Chronic Kidney Disease Epidemiology...
OBJECTIVE The aim of this study was to evaluate the association urinary cystatin C, a tubular damage marker, with progression type 2 diabetic nephropathy. RESERCH DESIGN AND METHODS baseline values serum and C were measured as primary parameters those nonalbumin protein (NAP) secondary parameters. In prospective observational study, total 237 patients followed up for 29 months (13–44 months). RESULTS Both C-to-creatinine ratio (CCR) NAP-to-creatinine (NAPCR) significantly different according...
Objective Although α-klotho is known as an anti-aging, antioxidant, and cardio-renal protective protein, the clinical implications of soluble levels in patients with diabetes have not been evaluated. Therefore, this study evaluated whether plasma urinary are associated albuminuria kidney disease diabetes. Research Design Methods A total 147 type 2 25 healthy control subjects were enrolled. The urine concentrations analyzed by enzyme-linked immunosorbent assay. Results Plasma (572.4 pg/mL...
Visual processing in the retina depends on coordinated signaling by interneurons. Photoreceptor signals are relayed to ∼20 ganglion cell types through a dozen excitatory bipolar interneurons, each responsive light increments (ON) or decrements (OFF). ON and OFF pathways become tuned specific connections with inhibitory interneurons: horizontal amacrine cells. A major obstacle for understanding retinal circuitry is unknown function of most ∼30–40 types, which synapses onto subset terminals,...
The aim of this study was to evaluate the influence coexistent Hashimoto's thyroiditis with papillary thyroid carcinoma on lymph node metastasis.The group defined by presence autoantibodies or pathologic confirmation. control did not have autoantibodies, disease, ultrasound findings thyroiditis.For group, only central metastasis had a lower frequency and mean number metastatic nodes than in after adjustment. With regard lateral involvement, there no significant difference between 2 groups....
We studied the efficacy and safety of acarbose in comparison with voglibose type 2 diabetes patients whose blood glucose levels were inadequately controlled basal insulin alone or combination metformin (or a sulfonylurea). This study was 24-week prospective, open-label, randomized, active-controlled multi-center study. Participants randomized to receive either (n=59, 300 mg/day) (n=62, 0.9 mg/day). The mean HbA1c at week 24 significantly decreased approximately 0.7% from baseline both (from...
Renal dysfunction, a major complication of type 2 diabetes, can be predicted from estimated glomerular filtration rate (eGFR) and protein markers such as albumin concentration. Urinary biomarkers may used to monitor or predict patient status. Urine samples were selected patients enrolled in the retrospective diabetic kidney disease (DKD) study, including 35 with good 19 poor prognosis. After removal immunoglobulin, remaining proteins reduced, alkylated, digested, analyzed qualitatively...
Background: Combination therapy with liothyronine (LT3) and levothyroxine (LT4) is used in patients persistent symptoms, despite being administered an adequate dose of LT4. LT3 may also be some thyroid cancer preparing for radioactive iodine therapy. However, there a controversy regarding the safety use, has been no definite evidence long-term Asian populations. The aim this study was to examine using Common Data Model (CDM). Methods: We conducted retrospective multicenter across four...
The aim of this study was to evaluate the association between urinary nonalbumin protein (NAP) and tubular markers in early diabetic nephropathy.Urinary NAP measured 118 patients with type 2 diabetes estimated glomerular filtration rates (eGFR) ≥60 mL/min/1.73 m². Urine levels [kidney injury molecule (KIM)-1, neutrophil gelatinase-assoicated lipocalin (NGAL) liver-type fatty acid-binding (L-FABP)] were by using an Enzyme-linked immunosorbent assay (ELISA). Patients divided into three groups...
The BRAF(V600E) mutation represents a novel indicator of the progression and aggressiveness papillary thyroid carcinoma (PTC). purpose this study was to determine clinical significance free circulating mutant in predicting advanced disease PTC.Seventy seven matched tumor plasma samples obtained from patients with both benign PTC were analyzed for using peptide nucleic acid (PNA) clamp real-time polymerase chain reaction (PCR).The absent DNA follicular adenomas or adenomatous goiter. In...
Previous studies have reported that uterine leiomyoma (UL) may share pathogenic features with obesity and hypertension, which are components of metabolic syndrome (MetS). We examined the association between UL MetS in premenopausal parous women. This 1:1 case–control study was conducted on 615 asymptomatic women without were matched for age, reproductive history, hormonal use, who underwent a comprehensive health examination. diagnosed by gynecologist based transvaginal ultrasonography...
To assess the time to initiation of insulin therapy, and concurrently investigate both patient- physician-related factors associated with delaying therapy in Korean patients type 2 diabetes uncontrolled by oral hypoglycemic agents (OHAs).This prospective, observational disease registry study was carried out across 69 centers Korea. Type who had received two or more OHAs within past 5 years, a glycated hemoglobin ≥8% 6 months not were included. Data recorded on data collection forms during...