Sophie Greif

ORCID: 0000-0003-1315-8766
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About
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Research Areas
  • Clinical Nutrition and Gastroenterology
  • Gastrointestinal motility and disorders
  • Diet and metabolism studies
  • Dysphagia Assessment and Management
  • Nutrition and Health in Aging
  • Chronic Disease Management Strategies
  • Abdominal Surgery and Complications
  • Diabetes Treatment and Management
  • Gastroesophageal reflux and treatments
  • Health and Medical Studies
  • Organ Transplantation Techniques and Outcomes
  • Intestinal and Peritoneal Adhesions

Charité - Universitätsmedizin Berlin
2022-2024

Freie Universität Berlin
2022-2024

Humboldt-Universität zu Berlin
2022-2023

Background: Quality of life (QoL) data chronic intestinal failure (cIF) patients treated with the GLP-2 analogue teduglutide are scarce. This study aims to analyze QoL changes over time in teduglutide-treated and compare results a matched non-treated cIF control group real-world setting. Methods: (SF-36 SBS-QoLTM) were obtained from adult being compared previously collected PNLiver trial (DRKS00010993), during which had been therapy naive. The dataset was then extended by pairwise...

10.3390/nu15081949 article EN Nutrients 2023-04-18

International practice guidelines for high-stool-output (HSO) management in short bowel syndrome (SBS) are available, but data on implementation lacking. This study describes the approach used to manage HSO SBS patients across different global regions. is an international multicenter evaluating medical of using a questionnaire survey. Thirty-three intestinal-failure centers were invited complete survey as one multidisciplinary team. Survey response rate was 91%. Dietary recommendations...

10.3390/nu15122763 article EN Nutrients 2023-06-16

The human intestinal tract reacts to extensive resection with spontaneous adaptation. We analyzed whether gene expression analyses or permeability (IP) testing could provide biomarkers describe regulation mechanisms in the barrier short bowel syndrome (SBS) patients during adaptive response treatment glucagon-like peptide-2 analog teduglutide.Relevant regions of GLP-2 receptor were sequenced. Gene and immunohistochemistry performed from mucosal biopsies. IP was assessed using a carbohydrate...

10.3390/nu15194220 article EN Nutrients 2023-09-29

Continuous Glucose Monitoring Following Consumption of Everyday Foods and their Effect on Postprandial Insulin Levels

10.1055/s-0043-1768089 article EN Aktuelle Ernährungsmedizin 2023-05-01

Einleitung Die Lebensqualität von parenteral ernährten Patient*innen mit Kurzdarmsyndrom ist durch Diarrhoen, Schlafunterbrechungen und Abhängigkeit der parenteralen Therapie deutlich reduziert zeigt trotz Steigerung des Langzeitüberlebens keine Verbesserung innerhalb letzten 20 Jahre. Seit Zulassung GLP-2 Analogons Teduglutid steht erstmalig eine spezifische für Patienten zur Reduktion notwendigen Verfügung. In den durchgeführten 24-Wochen Phase-III-Studien konnte jedoch kein positiver...

10.1055/s-0043-1771771 article DE Zeitschrift für Gastroenterologie 2023-08-01
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