A5102757469- Chaos control and synchronization
- Surface Treatment and Residual Stress
- Brake Systems and Friction Analysis
- Erosion and Abrasive Machining
- Adhesion, Friction, and Surface Interactions
- Gear and Bearing Dynamics Analysis
- Advanced Surface Polishing Techniques
- Advanced machining processes and optimization
- Metal and Thin Film Mechanics
- Lubricants and Their Additives
- Laser Material Processing Techniques
- Neuroscience and Neural Engineering
- Muscle activation and electromyography studies
- Musculoskeletal pain and rehabilitation
- Inflammasome and immune disorders
- Advanced materials and composites
- Tribology and Wear Analysis
- Advanced Memory and Neural Computing
- Adsorption and Cooling Systems
- Phytoestrogen effects and research
- Machine Fault Diagnosis Techniques
- Mechanical stress and fatigue analysis
- Tensor decomposition and applications
- Liver physiology and pathology
- Surface Treatment and Coatings
Sun Yat-sen University
2024-2025
Sun Yat-sen University Cancer Center
2024-2025
Zhejiang University of Technology
2019-2024
State Key Laboratory of Oncology in South China
2024
Universiti Putra Malaysia
2022-2023
Jiangsu University
2023
Soochow University
2023
Hunan Normal University
2022
China University of Mining and Technology
2015-2021
Zhejiang University
2020
Abstract The gradient nanostructure is machined on the aluminum (Al) alloy by two-dimensional ultrasonic surface burnishing process (2D-USBP). mechanism of why enhances wear resistance investigated. mechanical properties and microstructure characterization for are performed operating a nanoindenter, transmission electron microscopy (TEM), backscattered diffraction (EBSD). Dry tests samples before after machining to evaluate mechanisms. effect explored developing crystal plasticity (CP)...
Friction experiments are conducted on a ring-on-disk tribometer, and friction noise produced during the process is extracted by microphone. The phase trajectory chaotic parameters of obtained phase-space reconstruction, its attractor evolution analyzed. results indicate that because largest Lyapunov exponent positive. follows "convergence-stability-divergence" pattern process. begins forming in running-in process, correlation dimension D increases gradually. In stable remains steady, stable....
Tangential ultrasonic vibration and vertical are applied in the surface burnishing process (SBP) to study improvement mechanism of both on machining performance. The force is collected by a Kistler sensor. roughness (Sa, Sq, Ssk, Sku) cross-section hardness machined samples characterized. A molecular dynamic model established discuss acoustic softening effect. Experimental results show that can reduce normal (Fz) value process. Meanwhile, tangential suppress volatility X-axis direction (Fx)...
The connection between amino acid metabolism and pyroptosis remains elusive. Herein, we screen the effect of individual on identify that methionine inhibits GSDME-mediated pyroptosis. Mechanistic analyses unveil MYO6, a unique actin-based motor protein, bridges GSDME N-terminus (GSDME-NT) endocytic adaptor AP2, mediating endolysosomal degradation GSDME-NT. This is increased by methionine-derived metabolite spermidine noncanonically direct binding to which enhances MYO6 selectivity for...
Abstract A novel two-dimensional ultrasonic surface burnishing process (2D-USBP) is proposed. 7075-T6 aluminum samples are processed by a custom-designed 2D-USBP setup. Parameter optimization of conducted to determine the best processing strategy aluminum. uniform design method utilized optimize process. U 13 (13 3 ) and 7 (7 2 tables established conduct parameter optimization. Burnishing depth, spindle speed, feed rate taken as control parameters. The roughness Vickers hardness evaluation...
Abstract Burnishing experiments with different burnishing parameters were performed on a computer numerical control milling machine to characterize the surface roughness of an aluminum alloy during burnishing. The chaos theory was employed investigate nonlinear features system. experimental results show that power spectrum is broadband and continuous, Lyapunov exponent λ positive, proving has chaotic characteristics. characteristic parameter, correlation dimension D , sensitive time behavior...
Abstract In order to explore the mechanism of unidirectional ultrasonic vibration-assisted machining from a microscopic point view, molecular dynamic (MD) simulation method is used simulate scratch process monocrystalline copper under excitation. By comparing results traditional scratching and scratching, influences vibration on surface morphology, tangential force, evolution crystal’s internal defects are discussed. The show that can improve quality workpiece, reduce energy consumption....
Type I IFNs (IFN-Is) induced by radiotherapy (RT) are critical for its efficacy, while the mechanism which tumor cells inhibit IFN-I production remains largely unsolved. By an unbiased CRISPR screen, we identified hemeoxygenase 1 (HO-1) as RT-related regulator of production. Mechanistically, ER-anchored, full-length HO-1 disrupted stimulator IFN genes (STING) polymerization and subsequent coat protein complex II-mediated (COPII-mediated) ER-Golgi transportation, leading to hampered...
To explore the recursive characteristics of a running-in attractor, recurrence plot (RP) and parameters are used to investigate dynamic features structure. The attractor is constructed based on friction noise signals generated from ring-on-disk wear experiments. RPs then reproduced in two-dimensional space. Recursive parameters, rate (RR), entropy (ENTR), trend (RT) calculated. Results show that RP evolves disrupted pattern homogeneous returns entire process, corresponding...
A feature parameter was proposed to quantitatively explore the boundedness of running-in attractors; its variation throughout friction process also investigated. The enclosing radius R built with recurrence plots (RPs) and qualification analysis (RQA) by using time delay embedding phase space reconstruction. Additionally, typology RPs rate (RR) were investigated verify applicability in characterizing process. Results showed that is larger at beginning, but exhibits a downward trend process;...
Irinotecan is the first line chemotherapy drug used for treatment of metastatic colorectal cancer worldwide. There increasing evidence suggesting that liver damage, including steatosis and steatohepatitis, can be caused during involving irinotecan. However, molecular mechanisms by which irinotecan-induced injury remain elusive. In this study, we found irinotecan significant elevation ALT, inflammation, fat accumulation in liver, are associated with hepatic macrophage activation. Depletion...
BACKGROUND:Severe sepsis is among the most common causes of death in Emergency Departments, with more than 30% mortality. Hydrocortisone used severe patients who were not responsive to fluid resuscitation and vasopressor therapy. However, effect hydrocortisone on regulating inflammation, hemodynamic stability, preventing shock still unclear Chinese patients. MATERIAL AND METHODS:In this prospective observational study, we included 105 We measured level serum inflammatory cytokines,...
The running-in attractor is a chaotic with stability, which forms in the process. Its “formation-stabilization-disappearance” stage can reflect dynamic features of nonlinear friction system. To reveal and evolution attractor, this work, wear experiments are implemented on ring-on-disk tribometer. coefficient signals then extracted reconstructed. Based reconstructed matrix signals, convergence (CON) standard deviation distance (STD) proposed. Results show that CON evolves from an increase to...
Abstract To investigate the influence of surface roughnesses on dynamic characteristics AISI 5120 steel in sliding friction process, a suite running-in experiments are performed pin-on-disk tribometer. The attractor is used to analyze high-dimensional features system under different roughnesses. experimental results show that original surfaces evolve same value stable wear stage. has chaotic nature and exists attractor. disk Ra = 0.953 μm most conducive shorten duration, reduce coefficient...
Wear experiments are performed to explore dynamic states changes of friction noise signals. A new characteristic parameter, moving cut data-approximate entropy (MC-ApEn), is adopted quantitatively recognize states. Additionally, determinism (DET), one key parameter recurrence quantification analysis, applied verify the reliability recognition results MC-ApEn. Results illustrate that MC-ApEn has distinct in different wear processes, and it can accurately detect abrupt change points for noise....