A5045909045- Erythrocyte Function and Pathophysiology
- Blood groups and transfusion
- Blood transfusion and management
- Thermal Radiation and Cooling Technologies
- Advanced Electron Microscopy Techniques and Applications
- Thermal properties of materials
- Blood disorders and treatments
- Plasmonic and Surface Plasmon Research
- Strong Light-Matter Interactions
- Electron and X-Ray Spectroscopy Techniques
- Immune Response and Inflammation
- Neonatal Health and Biochemistry
- Mechanical and Optical Resonators
- Antimicrobial Peptides and Activities
- Near-Field Optical Microscopy
- Lysosomal Storage Disorders Research
- Photoacoustic and Ultrasonic Imaging
- Botanical Research and Chemistry
- Silicon Nanostructures and Photoluminescence
- Quantum Dots Synthesis And Properties
- RNA modifications and cancer
- Neurological and metabolic disorders
- Gold and Silver Nanoparticles Synthesis and Applications
- Ferroelectric and Piezoelectric Materials
- Nanowire Synthesis and Applications
University of Washington
2019-2024
Seattle University
2021-2022
Scripps Research Institute
1992-2016
The unique optical properties of surface plasmon resonances in nanostructured materials have attracted considerable attention, broadly impacting both fundamental research and applied technologies ranging from sensing optoelectronics to quantum computing. Electron energy-loss spectroscopy (EELS) the transmission electron microscope has revealed valuable information about full plasmonic spectrum these with nanoscale spatial resolution. Here we report a novel approach for experimentally...
Herein, we report studies leading to the discovery of neoseptins and a comprehensive examination structure-activity relationships (SARs) this new class small-molecule mouse Toll-like receptor 4 (mTLR4) agonists. The compounds in class, which emerged from screening an α-helix mimetic library, stimulate immune response, act by well-defined mechanism (mouse TLR4 agonist), are easy produce structurally manipulate, exhibit exquisite SARs, nontoxic, elicit improved qualitatively different...
The ability to control and manipulate temperature at nanoscale dimensions has the potential impact applications including heat-assisted magnetic recording, photothermal therapies, temperature-driven reactivity. One challenge with controlling nanometer is need mitigate heat diffusion, such that only changes in well-defined nanoscopic regions of sample. Here we demonstrate use far-field laser excitation actively shape thermal near-field individual gold nanorod heterodimers by resonantly...
Free-electron-based measurements in scanning transmission electron microscopes (STEMs) reveal valuable information on the broadband spectral responses of nanoscale systems with deeply subdiffraction limited spatial resolution. Leveraging recent advances manipulating phase profile transverse wavefront, we theoretically describe interactions between probe and optically stimulated nanophotonic targets which gains energy while simultaneously transitioning states distinct profiles. Exploiting...
Exciton polaritons (EPs) are ubiquitous light-matter excitations under intense investigation as test beds of fundamental physics and components for all-optical computing. Owing to their unique attributes facile experimental tunability, EPs potentially enable strong nonlinearities, condensation, superfluidity at room temperature. However, the diffraction limit light momentum content fast electron probes preclude characterization in nanoscale structured cavities exhibiting energy-momentum...
Creating next-generation devices capable of transducing waste heat into useful work will require building blocks designed to direct low-grade thermal energy at length scales well below the diffraction limit. Characterizing thermally induced transfer nanoscale, however, is a formidable task due simultaneous demand high spatial and spectral resolution infrared energies. Leveraging recent advancements in electron loss (EEL) gain (EEG) spectroscopy, we reveal that individual nanostructures can...
The ability of nanophotonic cavities to confine and store light nanoscale dimensions has important implications for enhancing molecular, excitonic, phononic, plasmonic optical responses. Spectroscopic signatures processes that are ordinarily exceedingly weak such as pure absorption Raman scattering have been brought the single-particle limit detection, while new emergent polaritonic states matter realized through coupling material photonic cavity degrees freedom across a wide range...
Refinements in energy monochromation and aberration correction state-of-the-art scanning transmission electron microscopes has opened access to the far infrared regime for spectroscopic characterization at nanoscale. At these low energies, dielectric environment, such as a slab adjacent target specimen, may no longer play passive role spectrum. Instead, environment itself host resonances that mix with those of complicate interpretation its spectral responses. This paper explores theoretical...
Journal Article Spectroscopy of Nanosphere-Substrate Coupling: The Role Multipolar Surface Phonon Modes Get access K Y Lee, Lee Department Materials Science and Engineering, McMaster University, Hamilton, ON, Canada Search for other works by this author on: Oxford Academic Google Scholar E Beutler, Beutler Chemistry, University Washington, Seattle, USA D J Masiello, Masiello M Lagos CanadaCanadian Centre Electron Microscopy, Corresponding author: mjlagos@mcmaster.ca Microscopy Microanalysis,...
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