A5010481962- Hepatocellular Carcinoma Treatment and Prognosis
- Fluid Dynamics and Heat Transfer
- Aortic aneurysm repair treatments
- Aerosol Filtration and Electrostatic Precipitation
- Wind and Air Flow Studies
- Fluid Dynamics and Turbulent Flows
- Aerodynamics and Acoustics in Jet Flows
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic Disease and Treatment Approaches
- Heat Transfer and Optimization
- Heat Transfer Mechanisms
- Heat Transfer and Boiling Studies
- Plant Surface Properties and Treatments
- Gas Dynamics and Kinetic Theory
- Advanced Radiotherapy Techniques
- Cyclone Separators and Fluid Dynamics
- Inhalation and Respiratory Drug Delivery
- Problem and Project Based Learning
- Electrohydrodynamics and Fluid Dynamics
- Organ Transplantation Techniques and Outcomes
- Aerodynamics and Fluid Dynamics Research
- Lattice Boltzmann Simulation Studies
- High voltage insulation and dielectric phenomena
- Polymer Foaming and Composites
- Fluid Dynamics and Thin Films
Universidad de Navarra
2014-2025
Navarre Institute of Health Research
2016-2025
Centro de Estudios e Investigaciones Técnicas de Gipuzkoa
2009-2018
KTH Royal Institute of Technology
2003-2009
University of Gävle
2004-2009
Energiforsk (Sweden)
2005
The following valepotriates: valtrate and didrovaltrate, isolated from the roots of Valeriana wallichii D. C., as well baldrinal, a degradation product valtrate, were tested for their cytotoxic antitumor activities, respectively in vitro on cultured rat hepatoma cells (HTC line), vivo, female mice KREBS II ascitic tumors.
The pathology of the human abdominal aortic aneurysm (AAA) and its relationship to later complication intraluminal thrombus (ILT) formation remains unclear. hemodynamics in diseased aorta are hypothesized be a key contributor growth ILT. objective this investigation is establish reliable 3D flow visualization method with corresponding validation tests high confidence order provide insight into basic hemodynamic features for better understanding AAA seek potential treatment diseases. A...
Some of the latest treatments for unresectable liver malignancies (primary or metastatic tumours), which include bland embolisation, chemoembolisation, and radioembolisation, among others, take advantage increased arterial blood supply to tumours locally attack them. A better understanding factors that influence this transport may help improve therapeutic procedures by taking flow patterns designing catheters infusion systems result in injected beads having access tumour vasculature....
The objective of the present manuscript is three-fold: (i) to study detailed pressure field inside a patient-specific abdominal aortic aneurysm (AAA) model experimentally and numerically discuss its clinical relevance, (ii) validate number possible numerical options their ability predict experimental (iii) compare spatial drop in AAA before after formation intraluminal thrombus (ILT) for late disease development timeline. A finite volume method was used solve governing equations fluid flow...
Summary Liver radioembolization (RE) is a treatment option for patients with unresectable and chemorefractory primary metastatic liver tumours. RE consists of intra‐arterially administering via catheter radioactive microspheres that locally attack the tumours, sparing healthy tissue. Prior to RE, standard practice conduct treatment‐mimicking pretreatment assessment infusion 99m Tc‐labelled macroaggregated albumin microparticles. The usefulness this has been debated in literature, thus, aim...
Abstract Radioembolization (RE) with yttrium-90 ( 90 Y) microspheres, a transcatheter intraarterial therapy for patients liver cancer, can be modeled computationally. The purpose of this work was to correlate the results obtained methodology using in vivo data, so that computational tool could used optimization RE procedure. hepatic artery three-dimensional (3D) hemodynamics and microsphere distribution during were six Y-loaded infusions three hepatocellular carcinoma commercially available...
Experimental measurements in a spray cooling test rig have been carried out for several heat fluxes the heater and different volumetric with dielectric refrigerant R134a. Results of transfer sprayed film thickness are presented. The made high speed camera equipped long distance microscope. It has found that there is relation between variation average Nusselt number along boiling curve. regimes curve related not only but also changes thickness. qualitative analysis those variations served to...
Abstract Liver radioembolization is a promising treatment option for combating liver tumors. It performed by placing microcatheter in the hepatic artery and administering radiation‐emitting microspheres through arterial bloodstream so that they get lodged tumoral bed. In avoiding nontarget radiation, standard practice to conduct pretreatment, which location injection velocity are decided. However, between pretreatment actual treatment, some of parameters influence particle distribution can...
The present paper focuses on the linear spatial instability of a viscous two-dimensional liquid sheet bounded by two identical gas streams. Orr–Sommerfeld differential equations and boundary conditions flow configuration are numerically solved using Chebyshev series expansions collocation method. strong dependence parameters velocity profiles is proven both quadratic error functions to define base in shear layer. sensitivity growth rate changes dimensionless problem assessed. Regarding...
The goal of this work is to develop a framework for manufacturing nonuniform wall thickness replicas abdominal aortic aneurysms (AAAs). methodology was based on the use computed tomography (CT) images virtual modeling, additive initial physical replica, and vacuum casting process range polyurethane resins final rubberlike phantom. average resulting AAA phantom compared with corresponding patient-specific model, obtaining an dimensional mismatch 180 μm (11.14%). material characterization...
The maximum diameter (MD) criterion is the most important factor when predicting risk of rupture abdominal aortic aneurysms (AAAs). An elevated wall stress has also been linked to a high aneurysm rupture, yet an uncommon clinical practice compute AAA stress. purpose this study assess whether other characteristics geometry are statistically correlated with Using in-house segmentation and meshing algorithms, 30 patient-specific models were generated for finite element analysis (FEA). These...