A5024798269- Drug Solubulity and Delivery Systems
- Spectroscopy and Chemometric Analyses
- Spectroscopy Techniques in Biomedical and Chemical Research
- Protein purification and stability
- Granular flow and fluidized beds
- Analytical Chemistry and Chromatography
- Traffic control and management
- Traffic Prediction and Management Techniques
- Fault Detection and Control Systems
- Advanced Chemical Sensor Technologies
- Membrane Separation and Gas Transport
- Inhalation and Respiratory Drug Delivery
- Analytical Methods in Pharmaceuticals
- Injection Molding Process and Properties
- Transportation Planning and Optimization
- Innovative Microfluidic and Catalytic Techniques Innovation
- Pesticide Residue Analysis and Safety
- Advanced Statistical Process Monitoring
- Crystallization and Solubility Studies
- nanoparticles nucleation surface interactions
- International Law and Aviation
- Belt Conveyor Systems Engineering
- Catalytic Processes in Materials Science
- Construction Project Management and Performance
- Nanomaterials for catalytic reactions
AstraZeneca (Sweden)
2011-2024
Sweco (Sweden)
2014-2017
AstraZeneca (United Kingdom)
2007-2015
Linköping University
2014
Chalmers University of Technology
1984
Raman spectroscopy can be an alternative to near-infrared (NIR) for nondestructive quantitative analysis of solid pharmaceutical formulations. Compared with NIR spectra, spectra have much better selectivity, but subsampling was always issue assessment. in transmission mode has reduced this issue, since a large volume the sample is measured mode. The matrix, such as particle size drug substance tablet, may affect signal. In work, matrix effects and were systematically investigated...
Abstract The use of transmission Raman spectroscopy for quantitative assessment pharmaceutical tablets using different multivariate approaches was investigated. Although is most often used in backscatter geometry, this paper a approach utilized, where the scattered light detected at back side tablets. spectra were recorded dispersive spectrometer with 785 nm excitation laser and typical exposure time 10 s. loaded to 32‐position sample rack measured by an automated procedure. Tablets...
The micronization process of new compounds is usually performed based on an empirical basis with a limited understanding input material properties and potential challenges. This study focuses the fracture behavior small organic molecular crystals, by using particle shape surface energy analysis techniques as well modeling tools. These methodologies enable us to generate data ways working that can provide crucial information for future pharmaceutical development. shape, energy, mechanical...
The velocity based cell transmission model (CTM-v) is a discrete time dynamical that mimics the evolution of traffic field on highways. In this paper CTM-v used together with an ensemble Kalman filter (EnKF) for purpose sensor data assimilation. We present calibration framework and EnKF. consists two separate phases. first phase parameters fundamental diagram second demand parameters. Results from calibrated are presented highway stretch north Stockholm, Sweden.
Two new, orthogonal projections to latent structures (OPLS) based methods were proposed analyze hyperspectral images, enabling the visualization of multiple chemical compounds in one matrix without need extensive preprocessing. Both delivered images representing distribution ribbon similar more traditional multivariate curve resolution–alternating least squares (MCR‐ALS) method, but their image background was less dynamic resulting a stronger contrast. This indicated that successfully...
Urban traffic simulation models could benefit significantly from new validation methods with potential to reduce the time-consuming calibration and work needed before application of model evaluate city infrastructure or policy implementations. Current practice is validate locally through comparison point flow measurements travel times on some important routes. However, for many applications, level congestion in an entire area important. During last decade, several studies have found...
A theoretical study of strains and stresses in cycling conveyor belts strengthened by two layers high modulus cord (Kevlar®) was performed. Experimental were then built with cords varying twist their behavior fatigue investigated. The significance compression especially clarified, but the results yield much further information on engineering these fiber composite products.
Many analytical methods are based on liquid chromatography and typically the only measure of system stability is standards, injected repeatedly throughout sequence. In this paper, a novel approach presented, where run treated as process with chromatographic data product. It postulated that enhanced quality can be obtained through monitoring process, i.e., system, during For purpose, control (LCPC) has been developed. Here, several parameters, e.g., pressure at column injection valve,...