- Child and Adolescent Health
- Global Maternal and Child Health
- Primary Care and Health Outcomes
- Vaccine Coverage and Hesitancy
- Health Systems, Economic Evaluations, Quality of Life
- Childhood Cancer Survivors' Quality of Life
- Tuberculosis Research and Epidemiology
- Infant Development and Preterm Care
- HIV/AIDS Impact and Responses
- Health Policy Implementation Science
- Adolescent and Pediatric Healthcare
- Mental Health Treatment and Access
- Viral Infections and Outbreaks Research
- Ethics and Legal Issues in Pediatric Healthcare
- Breastfeeding Practices and Influences
- Chronic Disease Management Strategies
- Interprofessional Education and Collaboration
- COVID-19 and Mental Health
- COVID-19 epidemiological studies
- COVID-19 Digital Contact Tracing
- Health, psychology, and well-being
- Healthcare Systems and Technology
- Poverty, Education, and Child Welfare
- Pneumonia and Respiratory Infections
- Family and Patient Care in Intensive Care Units
University of Cape Town
2018-2024
Lung Institute
2019-2021
South African Tuberculosis Vaccine Initiative
2018-2021
University of East Anglia
2020
The King's College
2020
King's College Hospital
2020
University of KwaZulu-Natal
2017
Abstract Objectives To achieve universal health coverage, systems need to be strengthened support the consistent delivery of high-quality, evidence-informed care at scale. The aim National Institute for Health Research (NIHR) Global Unit on He A lth S ystem tr E ng T hening in Sub-Saharan Africa (ASSET) is address this a four-year programme spanning three healthcare platforms (primary integrated treatment chronic conditions adults, maternal and newborn, surgical care) involving eight work...
Nigeria, in its quest to strengthen primary healthcare system, is faced with a number of challenges including shortage clinicians and skills. Methods are being sought better equip for the clinical demands that they face. Using mentorship model between developers South Africa Nigerian clinicians, Practical Approach Care Kit (PACK) adult patients, health systems strengthening programme, has been localised piloted 51 facilities three states. Lessons learnt from this experience include value...
Abstract Objectives The adverse effects of the COVID‐19 pandemic on tuberculosis (TB) detection have been well documented. Despite shared symptoms, guidance for integrated screening TBand are limited, and opportunities health systems strengthening curtailed by lockdowns. We partnered with a high TB burden district in KwaZulu‐Natal, South Africa, to co‐develop an approach assessing TB, delivered using online learning quality improvement, evaluated its performance testing detection. Methods...
Personal and occupational experiences of COVID-19 their effects on South African health workers' wellbeing[3][4] We report findings from an online survey conducted between September November 2020 in the Amajuba District KwaZulu-Natal, reflecting first wave.It investigated risk factors for severe COVID-19, experience COVID-19-related problems, causes anxiety, psychological wellbeing.The was completed as part intervention intended to support primary care workers managing context a high...
Abstract Background Despite significant reductions in mortality, preventable and treatable conditions remain leading causes of death illness children South Africa. The PACK Child intervention, comprising clinical decision support tool (guide), training strategy health systems strengthening components, was developed to expand on WHO’s Integrated Management Childhood Illness programme, extending care under 5 years those aged 0–13 years, with chronic needing regular follow-up, integration...
Despite progress towards End TB Strategy targets for reducing tuberculosis (TB) incidence and deaths by 2035, South Africa remains among the top ten high-burden countries globally. A large challenge lies in how policies to improve detection, diagnosis treatment completion interact with social structural drivers of TB. Detailed understanding theoretical development contextual determinants problems care is required developing effective interventions. This article reports findings from...
Background The development of strategies to better detect and manage patients with multiple long-term conditions requires estimates the most prevalent condition combinations. However, standard meta-analysis tools are not well suited synthesising heterogeneous multimorbidity data. Methods We developed a statistical model synthesise data on associations between diseases nationally representative prevalence applied South Africa. Published unpublished were reviewed, meta-regression analysis was...
Despite significant reductions in mortality, preventable and treatable conditions remain the leading causes of death children under five within South Africa. The WHO's Integrated Management Childhood Illness (IMCI) programme has been widely implemented to address most common mortality five. Although effective, limitations IMCI scope adherence have emerged. Practical Approach Care Kit (PACK) Child guide developed expand on these limitations. It is intended as a clinical decision support tool...
The COVID-19 pandemic reversed much of global progress made in combatting tuberculosis, with South Africa experiencing one the largest impacts on tuberculosis detection. aim this paper is to share our experiences applying learning health systems (LHS) thinking codevelopment an intervention improving integrated response and a African district. A sequential partially mixed-methods study was undertaken between 2018 2021 district Amajuba KwaZulu-Natal. Here, we report formulation Theory Change,...
Abstract Objectives To achieve universal health coverage, systems need to be strengthened support the consistent delivery of high-quality, evidence-informed care at scale. The aim National Institute for Health Research (NIHR) Global Unit on He A lth S ystem tr E ng T hening in Sub-Saharan Africa (ASSET) is address this a four-year programme spanning three healthcare platforms (primary integrated treatment chronic conditions adults, maternal and newborn, surgical care) involving eight work...
Abstract Background South Africa’s first SARS-CoV-2 case was identified 5th March 2020 and national lockdown followed 26th. Households are an important location for secondary infection. Physical distancing sanitation – infection mitigation recommended by the World Health Organization (WHO) at time difficult to implement in limited-resource settings because of overcrowded living conditions. Methods This study (ClinicalTrials.gov NCT05119348) conducted from August September 2021 two densely...
The care of people with multiple long-term conditions (MLTCs) is complex and time-consuming, often denying them the agency to self-manage their conditions—or for clinician they visit provide streamlined, person-centred care. We reconfigured Practical Approach Care Kit, our established, evidence-based, policy-aligned clinical decision support tool low-resource primary settings, consolidated guidance a patient journey through facility. This places at centre that shifts screening, monitoring...
Abstract BackgroundDespite progress towards meeting End TB strategy targets for reducing tuberculosis (TB) incidence and deaths by 2035, South Africa remains among the top ten high-burden countries globally. A large challenge lies in how policies to improve detection, diagnosis treatment completion interact with social structural drivers of TB. Detailed understanding theoretical development contextual determinants problems care is required developing effective interventions. This article...
Abstract Background: Despite significant reductions in mortality, preventable and treatable conditions remain leading causes of death illness children aged under five South Africa. The PACK Child intervention, comprising a clinical decision support tool (guide), training strategy health systems strengthening components, was developed to expand on WHO’s Integrated Management Childhood Illness programme, 2017-2018 piloted 10 primary healthcare facilities the Western Cape Province. Here we...
Abstract Background: Despite significant reductions in mortality, preventable and treatable conditions remain leading causes of death illness children South Africa. The PACK Child intervention, comprising clinical decision support tool (guide), training strategy health systems strengthening components, was developed to expand on WHO’s Integrated Management Childhood Illness programme, extending care under 5 years those aged 0-13 years, with chronic needing regular follow-up, integration...
Abstract Background: Despite significant reductions in mortality, preventable and treatable conditions remain leading causes of death illness children South Africa. The PACK Child intervention, comprising clinical decision support tool (guide), training strategy health systems strengthening components, was developed to expand on WHO’s Integrated Management Childhood Illness programme, extending care under 5 years those aged 0-13 years, with chronic needing regular follow-up, integration...
Abstract Background The WHO’s Integrated Management of Childhood Illness (IMCI) has resulted in progress addressing infant and child mortality. However, unmet needs children continue to present a burden upon primary healthcare services. capacity services quality care offered require greater support address these by extending integrating curative preventive for the with long-term health condition older than 5, not prioritised IMCI. In response needs, PACK Child intervention was developed...
Abstract BACKGROUND: Innovative strategies like WHO’s Integrated Management of Childhood Illness (IMCI) have resulted in progress addressing infant and child mortality. However, the needs children continue to present a burden upon primary healthcare services. The capacity services quality care offered require greater support address these extend integrated curative preventive care, specifically, for well child, with long-term health condition older than 5 years, not included IMCI. In...
Abstract BACKGROUND: Innovative strategies like WHO’s Integrated Management of Childhood Illness (IMCI) have resulted in progress addressing infant and child mortality. However, the needs children continue to present a burden upon primary healthcare services. The capacity services quality care offered require greater support address these extend integrated curative preventive care, specifically, for well child, with long-term health condition older than 5 years, not included IMCI. In...
Abstract Background: The WHO’s Integrated Management of Childhood Illness (IMCI) has resulted in progress addressing infant and child mortality. However, unmet needs children continue to present a burden upon primary healthcare services. capacity services quality care offered require greater support address these by extending integrating curative preventive for the with long-term health condition older than 5, not prioritised IMCI. In response needs, PACK Child intervention was developed,...