A5015898412- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Infant Development and Preterm Care
- Neonatal and fetal brain pathology
- Congenital Heart Disease Studies
- Neonatal Health and Biochemistry
- Infant Nutrition and Health
- Pregnancy and preeclampsia studies
- Neuroscience of respiration and sleep
- Child and Adolescent Health
- Neonatal and Maternal Infections
- Respiratory Support and Mechanisms
- Congenital Anomalies and Fetal Surgery
- Pleural and Pulmonary Diseases
- Breastfeeding Practices and Influences
- Streptococcal Infections and Treatments
- Pneumonia and Respiratory Infections
- Retinopathy of Prematurity Studies
- Bacterial Infections and Vaccines
- Preterm Birth and Chorioamnionitis
- Hemoglobinopathies and Related Disorders
- Maternal and Neonatal Healthcare
- Nuclear Structure and Function
- Intestinal Malrotation and Obstruction Disorders
- Viral Infections and Immunology Research
Universidade do Porto
2016-2025
Lusíada University of Porto
2024-2025
Hospital de São João
2015-2024
CUF Porto Hospital
2024
Centro Universitário de João Pessoa
2024
Administração Regional de Saúde de Lisboa e Vale do Tejo
2024
Centro Hospitalar do Porto
2020-2021
Fairfax Neonatal Associates
2021
Centro de Neumologia Pediatrica
2021
Centre for Health Technology and Services Research
2014
Evaluate the hematological parameters and indices in blood count collected on first day of life (D1) very premature infants born to mothers with early-onset preeclampsia (PE) their correlation increased neonatal morbimortality. Changes hematologic counts after birth associated PE have been demonstrated by recent studies, although inconsistently. Retrospective study between 2008 2023, at a level III intensive care unit, including preterm gestational age below 30 weeks. A was D1 comparison...
Introduction: The challenge of maintaining normoxemia in preterm infants undergoing respiratory support and oxygen therapy has led to the development closed-loop automatic control systems for FiO2. aim this study was assess effectiveness these SpO2 within a target range (90% - 94%) neonates receiving supplemental oxygen.Methods: We conducted single-centre prospective over three-year period (2020 2023) including with gestational age < 33 weeks who received first 24 hours life either...
Late preterm delivery (74% of all births) increases the incidence respiratory pathology, namely distress syndrome (RDS), transient tachypnea newborn (TTN) and need ventilator support when compared to term delivery. The aim is evaluate morbimortality in late infants risk factors associated with RDS TTN.Descriptive retrospective study newborns 34+0 36+6 weeks gestational age, born at our center between September 1, 2012 August 31, 2015. Those major malformations, chromosomopathies, hydrops...
Purpose: To identify risk factors and predictors of severity associated with meconium aspiration syndrome (MAS) in the patients admitted to neonatal intensive care unit (NICU).Materials methods: Retrospective study including newborns admitted, between 2005 2015, a diagnosis MAS.Results: Of NICU, 0.66% were diagnosed MAS. These had higher prevalence caesarean delivery (p < .001), nonreassuring or abnormal cardiotocography (CTG) intrapartum maternal fever = .002), Apgar scores at first minute...
This study aims to characterize the drugs used in a Portuguese Neonatal Intensive Unit Care, assess rate of off-label or unlicensed use according information available Summary Product Characteristics and compare results between preterm full-term neonates.A 6-month period retrospective cross-sectional was conducted our Care 2013. Prescribed data were recorded compared with paediatric contained Characteristics.We analyzed 1011 prescriptions 84 active substances, made 218 admissions. In 42.9%...
Extremely low birth-weight (ELBW) preterm infants remain at high risk for mortality and major morbidities, nearly all need packed red blood cell transfusions within their first weeks of life. The overall objective this study was to assess the association between anemia admission neonatal intensive care unit (NICU) with morbidity in ELBW infants.This retrospective conducted on 106 patients admitted our level III NICU from January 2006 December 2015. subjects were divided into two groups: (1)...
Dedicated pediatricians in emergency departments (EDs) may be beneficial, though no previous studies have assessed the related costs and benefits/harms. We aimed to evaluate net benefits of dedicated a pediatric ED.Cost-consequences analysis visits ED tertiary hospital. Two Medical Teams (MT) were compared: MT-A (May-September 2012), with general pediatrics physicians only; MT-B 2013), pediatricians. The main outcomes analyzed relevant clinical outcomes, patient throughput time costs.We...
A retrospective chart review of 18 nonvaccinated newborns and infants admitted to 6 intensive care units in the north Portugal between 2007 2012 revealed a high rate admissions along with significant rates severe pulmonary hypertension mortality. Hyperleukocytosis was significantly associated more clinical picture
Mutations in the ALS2 gene cause three distinct disorders: infantile ascending hereditary spastic paraplegia, juvenile primary lateral sclerosis, and autosomal recessive amyotrophic sclerosis. We present a review of literature case 16-year-old boy who is, to best our knowledge, first Portuguese with paraplegia. Clinical investigations included sequencing analysis gene, which revealed heterozygous mutation exon 5 (c.1425_1428del p.G477Af<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
To evaluate nosocomial infections preventive bundle, implemented in April 2010 Centro Hospitalar de São João (CHSJ) Neonatal Intensive Care Unit (NICU) effectiveness.Newborns admitted to level-III NICU of CHSJ, between 1 2007 and 31 March 2013, with sepsis as discharge diagnosis, were selected divided into two periods (Period 2, before after new bundle introduction). Data from the compared.Nosocomial incidence density decreased significantly 8.6 4.8 per 1000 patient days Period 2. Nosocomial...
Introduction: Pneumothorax occurs more frequently in the neonatal period than any other of life and is associated with increased mortality morbidity. Several risk factors for pneumothorax, including respiratory pathology, invasive non-invasive support, predictors have been described.Objective: To evaluate prevalence to assess describe clinical characteristics, management outcome newborn infants as well identify these newborns.Methods: This retrospective case-control study included all...
Survival and outcomes for preterm infants with respiratory distress syndrome (RDS) have improved over the past 30 years. We conducted a study to assess changes in perinatal care delivery room management their impact on outcome of very low birth weight newborns, last 15 A comparison between two epochs was performed, periods before after 2005, when early nasal continuous positive airway pressure (NCPAP) Intubation-SURfactant-Extubation (INSURE) were introduced our center. Three hundred...
Data from previous studies have demonstrated inconsistency between current evidence and delivery room resuscitation practices in developed countries. The primary aim of this study was to assess the quality newborn healthcare Portuguese rooms, comparing with 2021 European Resuscitation Council guidelines. secondary compare consistency tertiary non-tertiary centers across Portugal.
Several studies assessed the influence of a low birth weight on bronchopulmonary dysplasia (BPD), but not all could find significant association. Our aim was to assess association between and BPD in preterm infants, prospectively recruited at 11 level III Portuguese neonatal centers.Obstetrical data mothers infants with gestational ages 24 30 weeks, born during 2015 2016 after surveilled pregnancy, were analyzed. Neonates considered small for age (SGA) when their birthweight below 10th...
BACKGROUND: Fetal inflammatory response syndrome (FIRS), the fetal equivalent of chorioamnionitis, is associated with poorer neonatal outcomes. FIRS diagnosed through placental histology, namely by identification funisitis (inflammation umbilical cord) and chorionic vasculitis vessels within plate). The aim this study was to identify evaluate associations between outcomes in preterm neonates. METHODS: We performed a retrospective cohort at level III intensive care unit (NICU), from January...
Pleural effusions are rare in the newborn. Still, being familiar with this condition is relevant given its association a wide range of disorders. Only two large series cases on matter have been published, no solid conclusions established. The aim study to determine etiology, management and prognosis pleural population high-risk neonates.The authors performed retrospective Neonatal Intensive Care Unit “Hospital de Sao Joao”, Porto (Portugal), between 1997 2014, all newborns diagnosis...
Grunting respirations occurring in the first hours of life is a frequent nonspecific clinical sign. Our objective was to assess significance grunting lasting over two birth term and near newborns.A five years retrospective study all newborns ≥35+0 weeks gestational age admitted for level III Neonatal Intensive Care Unit (NICU).Prolonged occurred 1.2% delivered newborns. Data on 151 grunter 302 controls were reviewed. Higher mother's age, pregnancy complications, lower male gender,...