A5067862765- Air Quality and Health Impacts
- Energy and Environment Impacts
- Carcinogens and Genotoxicity Assessment
- Climate Change and Health Impacts
- Toxic Organic Pollutants Impact
- Air Quality Monitoring and Forecasting
- Inhalation and Respiratory Drug Delivery
- Atmospheric chemistry and aerosols
- Nanoparticles: synthesis and applications
- Municipal Solid Waste Management
- Catalytic Processes in Materials Science
- Thyroid Cancer Diagnosis and Treatment
- Health, Medicine and Society
- Odor and Emission Control Technologies
- Advanced Chemical Sensor Technologies
- Vehicle emissions and performance
- Aeolian processes and effects
- Thyroid Disorders and Treatments
- Thyroid and Parathyroid Surgery
- International Environmental Law and Policies
- Digital literacy in education
- Water Quality Monitoring and Analysis
- Experimental Learning in Engineering
- Extracellular vesicles in disease
- Telecommunications and Broadcasting Technologies
Université du littoral côte d'opale
2016-2025
Ghent University Hospital
2024
Centre National de la Recherche Scientifique
2020-2021
Centre Hospitalier Universitaire de Besançon
2016-2018
Centre d'Investigation Clinique - Innovation Technologique
2016
Centre Hospitalier Universitaire de Grenoble
2016
Université Lille Nord de France
2009-2015
Université de Lille
2010
Laboratoire Catalyse et Spectrochimie
2008
Catalyse
2006-2007
Compelling evidence indicates that exposure to air pollution particulate matter (PM) affects human health. However, how PM composition interacts with PM-size cause adverse health effects needs elucidation. In this study, we were also interested in the physicochemical characteristics and toxicological end points of PM₂.₅₋₀.₃ samples produced rural, urban, or industrial surroundings, thereby expecting differentiate their respective vitro bronchial epithelial cells (BEAS-2B). Physicochemical...
Abstract ABSTRACT: To contribute to improving knowledge on the adverse health effects induced by particulate matter (PM) air pollution, an extensive investigation was undertaken of underlying mechanisms action activated PM 2.5 pollution collected in Dunkerque, a strongly industrialized French seaside city. Their chemical and physical characteristics have been previously determined, earlier vitro short‐term studies shown them cause dose‐dependent time‐dependent oxidative damage, gene...
Abstract Exposure to high levels of air pollution particulate matter (PM) is strongly associated with increased pulmonary morbidity and mortality. However, the underlying mechanisms action whereby PM cause adverse health effects are still unclear. In developing countries, like in sub‐Saharian region Africa, people often exposed levels. Hence, three 2.5 samples were collected District Abidjan (Côte d'Ivoire), under rural, urban or industrial influences. Their most toxicologically relevant...
To extend current knowledge on the underlying mechanisms of air pollution particulate matter (PM(2.5))-induced human lung toxicity, metabolic activation polycyclic aromatic hydrocarbons (PAH) within PM(2.5) and PAH-DNA bulky stable adduct patterns in alveolar macrophage (AM) and/or epithelial L132 cells mono- cocultures were studied. In coculture system, only AM exposed to PM(2.5), unlike cells. Particles, inorganic fraction positive controls [i.e. TiO(2), thermally desorbed PM (dPM)...
Epidemiological studies have demonstrated the link between chronic exposure to particulate matter (PM), especially particles with an aerodynamic diameter lesser than 2.5 µm (PM(2.5) ), and lung cancer. Mechanistic investigations focus on contribution of various genotoxicants adsorbed onto particles, more particularly polycyclic aromatic hydrocarbons or nitroaromatics. Most previous dealing genotoxic and/or mutagenic measurements were performed organic extracts obtained from PM(2.5) collected...
Airborne particulate matter (PM) toxicity is of growing interest as diesel exhaust particles have been classified carcinogenic to humans. However, PM a mixture chemicals, and respective contribution organic inorganic fractions remains unclear. Thus, we analysed the link between chemical composition samples bulky DNA adduct formation supported by CYP1A1 1B1 genes induction catalytic activities. We used six native samples, collected in industrial, rural or urban areas, either during summer...
Sea breeze (SB) phenomena may strongly influence air quality and lead to important effects on human health. In order study the impact of SB dynamics properties toxicity aerosols, an atmospheric mobile unit was deployed during a field campaign performed in urbanized industrialized coastal area Northern France. This combines aerosol samplers, two scanning lidars (Doppler elastic) air-liquid interface (ALI, Vitrocell®) vitro cell exposure device. Our highlights that after passage front, top...