Ling Sun

ORCID: 0000-0003-1380-4692
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About
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Research Areas
  • Pulmonary Hypertension Research and Treatments
  • Muscle Physiology and Disorders
  • Image Processing and 3D Reconstruction
  • Neurological disorders and treatments
  • Calcium signaling and nucleotide metabolism
  • Food Supply Chain Traceability
  • Cardiomyopathy and Myosin Studies
  • Animal Nutrition and Physiology
  • Electrochemical Analysis and Applications
  • Cancer-related molecular mechanisms research
  • Wood and Agarwood Research
  • Genomics and Rare Diseases
  • Remote Sensing and Land Use
  • Non-Invasive Vital Sign Monitoring
  • Electronic Packaging and Soldering Technologies
  • Animal Genetics and Reproduction
  • Genomic variations and chromosomal abnormalities
  • 3D IC and TSV technologies
  • Congenital Heart Disease Studies
  • Congenital heart defects research
  • Protein Tyrosine Phosphatases
  • Genetic and phenotypic traits in livestock
  • Electrochemical sensors and biosensors
  • Animal Behavior and Welfare Studies
  • Parkinson's Disease Mechanisms and Treatments

Tianjin Institute of Industrial Biotechnology
2025

Chinese Academy of Sciences
2023-2025

Intelligent Synthetic Biology Center
2025

Guangdong Academy of Medical Sciences
2021-2025

Guangdong Provincial People's Hospital
2021-2025

Soochow University
2011-2025

Tianjin Anding Hospital
2025

Tianjin Medical University
2025

Huazhong Agricultural University
2010-2025

Ministry of Education of the People's Republic of China
2021-2025

Respiration rate (RR) and heartbeat (HR) are important physiological parameters for a person. Impulse radio ultra-wideband (IR-UWB) is promising technology non-contact sensing monitoring. This brief presents new method based on autocorrelation to measure the RR HR using IR-UWB radar. The correlation coefficient waveform contains vital sign signals, overcoming effect of noise clutter. Applying fast Fourier transform, respiration frequency can be acquired easily. A clever also proposed locate...

10.1109/tcsii.2018.2860015 article EN IEEE Transactions on Circuits & Systems II Express Briefs 2018-07-26

Abstract Background Many genetic syndromes (GSs) have distinct facial dysmorphism, and gestalts can be used as a diagnostic tool for recognizing syndrome. Facial recognition technology has advanced in recent years, the screening of GSs by become feasible. This study constructed an automatic model identification children with GSs. Results A total 456 frontal photos were collected from 228 healthy Guangdong Provincial People's Hospital Jun 2016 to Jan 2021. Only one image was selected each...

10.1186/s13023-021-01979-y article EN cc-by Orphanet Journal of Rare Diseases 2021-08-03

Formolase catalyzes the carboligation of C1 compound formaldehyde, providing a unique opportunity for producing multicarbon compounds with formaldehyde as sole substrate. Elucidating molecular rationale determining activity formolase, especially at low concentrations is essential improving its catalytic performance in conversion. In this study, channel-modulating helix formed zipper structure neighboring that was identified to regulate formolaseBFD, formaldehyde. Up 24.1-fold increased...

10.1021/acscatal.4c07452 article EN ACS Catalysis 2025-01-14

Abstract A big diameter bioresorbable scaffold is expected to be used for treatment of vessel stenosis children with congenital heart disease adapt the growth characteristics and avoid late adverse events permanent stent implanted in children. However, it challenging fabricate a that appropriate percutaneous implantation enough mechanical performance can smoothly delivered children’s small vessel. In this study, novel iron & Scaffold (BBS) pulmonary artery cardiovascular diseases was...

10.1093/rb/rbaf041 article EN cc-by Regenerative Biomaterials 2025-05-13

Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a leading cause of sudden cardiac death (SCD) in young patients, characterized by bidirectional or often induced physical exertion emotional stress. Results We analyzed 12-year-old girl with CPVT who suffered and respiratory arrest. Clinical data were derived from medical records. Whole-exome sequencing (WES) Sanger identified two missense mutations the trans-2,3-enoyl-CoA reductase-like ( TECRL ) gene...

10.3389/fped.2025.1549827 article EN cc-by Frontiers in Pediatrics 2025-05-16

This paper presents a real-time system that can monitor an infant's respiration and detect apnea when it occurs. For infants, bedside monitoring of respiratory signals using noncontact sensors is desirable at the hospital for in-home care. Traditional approach employs acoustic which hardly infant breathing due to low SNR. In this paper, novel method introduced by ultra-wideband (UWB) radar obtains signal from weak chest vibration. Furthermore, advanced processing techniques are proposed...

10.1109/icct.2015.7399885 article EN 2015-10-01

Background: Common cardiac abnormalities in Noonan syndrome (NS) include congenital heart diseases (CHD), pulmonary valve stenosis and hypertrophic cardiomyopathy (HCM). Molecular diagnoses are enabling earlier more precise diagnosis of patients who have a subtle or atypical presentation. The aims this study were to investigate genotype-phenotype associations with respect (NS)-associated catheter surgery-based interventions conditions. Methods: From January 2019 December 2021, 22 children...

10.3389/fgene.2022.915129 article EN cc-by Frontiers in Genetics 2022-06-13

Background Noonan syndrome (NS), a genetically heterogeneous disorder, presents with hypertelorism, ptosis, dysplastic pulmonary valve stenosis, hypertrophic cardiomyopathy, and small stature. Early detection assessment of NS are crucial to formulating an individualized treatment protocol. However, the diagnostic rate pediatricians pediatric cardiologists is limited. To overcome this challenge, we propose automated facial recognition model identify using novel deep convolutional neural...

10.3389/fgene.2021.669841 article EN cc-by Frontiers in Genetics 2021-06-07

With the demand for standardized large-scale livestock farming and development of artificial intelligence technology, a lot research in area animal face detection identification was conducted. However, there are no specialized studies on normalization, which may significantly reduce performance identification. The keypoint has been widely applied human is not suitable normalization due to arbitrary directions images captured from uncooperative animals. It necessary develop method that can...

10.3390/ani13091446 article EN cc-by Animals 2023-04-24

Abscisic acid (ABA) plays an important regulatory role in plants. It is very critical to obtain the dynamic changes of ABA situ for botanical research. Herein, coupled with paper-based analysis devices, electrochemical immunoelectrodes based on disposable stainless steels sheet were developed detection plants situ. The steel sheets modified carbon cement, ferrocene-graphene oxide-multi walled nanotubes nanocomposites, and antibodies. system can detect range 1 nM 100 μM, a limit pM. content...

10.1021/acs.jafc.4c03594 article EN Journal of Agricultural and Food Chemistry 2024-07-25

At present, the accuracy of text detection from natural scene images based on deep learning is much higher than that traditional algorithm. However, most detectors should use large-scale neural network models (such as VGG and ResNet) for improving accuracy. Because weight files these are very large (VGG about 500MB ResNet 100MB), they not suitable computationally limited platforms in daily life. Based small-scale model named MobileNet V2, U-Net used semantic segmentation commonly, a detector...

10.1109/icma.2019.8816384 article EN 2022 IEEE International Conference on Mechatronics and Automation (ICMA) 2019-08-01

Background Pulmonary artery stenosis is often associated with congenital heart disease. The aim of the study was to evaluate efficacy and safety stenting for branch pulmonary using a biodegradable nitride iron stent (IBS ® Angel™) right ventricular systolic diastolic function. Methods From July 2021 February 2022, total 11 cases (ages ranged from 36 86 months old) were included in this pre post-intervention, prospective, cohort preclinical study. All underwent transthoracic echocardiographic...

10.3389/fcvm.2022.914370 article EN cc-by Frontiers in Cardiovascular Medicine 2022-08-01
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