A5079216554- Viral Infections and Immunology Research
- Bacterial Infections and Vaccines
- Infectious Encephalopathies and Encephalitis
- Influenza Virus Research Studies
- Migraine and Headache Studies
- Viral gastroenteritis research and epidemiology
- Microbial infections and disease research
- SARS-CoV-2 and COVID-19 Research
- Infectious Diseases and Tuberculosis
- Pharmacological Effects and Toxicity Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Multiple Sclerosis Research Studies
- Child and Adolescent Health
- Epilepsy research and treatment
- Palliative Care and End-of-Life Issues
- Pediatric Pain Management Techniques
- Childhood Cancer Survivors' Quality of Life
- Animal Virus Infections Studies
- Ethics and Legal Issues in Pediatric Healthcare
- Clinical Reasoning and Diagnostic Skills
- Diversity and Career in Medicine
- Mycobacterium research and diagnosis
- Emergency and Acute Care Studies
- Cardiac Arrest and Resuscitation
- Hepatitis Viruses Studies and Epidemiology
University of Colorado Denver
2017-2023
University of Pennsylvania
2023
Children's Hospital Colorado
2017-2022
University of Colorado Anschutz Medical Campus
2018-2022
Children's Hospital of Philadelphia
2018-2022
Pediatrics and Genetics
2020
University of California, San Diego
2018
Children's Hospital of Los Angeles
2018
Boston Children's Hospital
2018
Seattle Children's Hospital
2018
We describe long-term functional, neurodiagnostic, and psychosocial outcomes of a cohort 12 children from Colorado diagnosed with acute flaccid myelitis (AFM) in 2014.Children were assessed every 3 months for 1 year or until clinical resolution. Assessments included neurologic examination, MRI, EMG/nerve conduction studies (NCS), functional measures (Assisting Hand Assessment, Hammersmith Functional Motor Scale), Patient-Reported Outcomes Measurement Information System questionnaires.Eight...
To determine the safety, tolerability, and efficacy of fluoxetine for proven or presumptive enterovirus (EV) D68-associated acute flaccid myelitis (AFM).A multicenter cohort study US patients with AFM in 2015-2016 compared serious adverse events (SAEs), effects, outcomes between fluoxetine-treated untreated controls. Fluoxetine was administered at discretion treating providers data gathered retrospectively. The primary outcome change summative limb strength score (SLSS; sum Medical Research...
Abstract Among 182 children with influenza infection in 2016–2017, 18% had neurologic manifestations of (NMI), including seizures and encephalopathy; 85% these were infected the H3N2 strain. Children NMI 3.5-times-higher odds having a comorbidity than those without 10-fold increased hospitalization.
Background: Communication around serious illness is a core competency for all residencies. One-fifth of neurology residencies have no curriculum. Published curricula use didactics or role-play to assess confidence performing this skill without evaluation in clinical settings. The SPIKES mnemonic (Setting, Perception, Invitation, Knowledge, Empathy, Strategy/Summary) outlines 6 evidence-based steps communication illness. It unknown whether child residents can incorporate into Objective: To...
Pediatric headaches, including migraine, are a common reason for emergency department (ED) presentation. IV valproic acid (VPA) followed by oral VPA tapers often used to abort pediatric headache and reduce recurrence, though limited data exist regarding this approach. This study evaluated the effectiveness of treatment acute headaches in ED preventing return encounters.
Neuroimaging is often part of the workup for a pediatric patient presenting with seizure to an emergency department (ED). We aim evaluate when neuroimaging in ED children non–first-time seizure, or nonindex (NIS), associated acute change management (ACM).
Background: In May 2018, Children's Hospital Colorado (CHCO) noted an outbreak of enterovirus (EV) A71-associated neurologic disease.Methods: A case EV-associated disease was defined as any child presenting to CHCO with meningitis, encephalitis, acute flaccid myelitis (AFM), and/or seizures between March 1 and November 30, 2018 EV detected from a biologic specimen. EV-A71 cases were compared other during the same period. EV-A71-associated AFM also EV-D68-associated 2013-2018.Findings: Of...
Influenza A H1N1 and B are associated with neurological complications including seizures, encephalopathy encephalitis. However, this season, when H3N2 was the predominant strain, many patients were admitted manifestations of influenza (NMI). The study objectives to: 1) identify clinical characteristics children NMI 2) compare demographics influenza-positive controls. We conducted a retrospective cohort/case control at Children’s Hospital Colorado from Dec 2016-Apr 2017. reviewed medical...
Most patients with enterovirus (EV) D68-associated acute flaccid myelitis (AFM) have long-term disability. No effective therapies been identified. Fluoxetine is the only FDA-approved medication in vitro antiviral activity against EV-D68. This study retrospectively analyzed safety, tolerability, and efficacy of fluoxetine for EV-D68-associated AFM. A multicenter cohort US children AFM 2015–2016 compared serious adverse events (SAEs), effects, outcomes between fluoxetine-treated untreated...
Abstract Background Several enteroviruses (EVs), including EV-A71 and EV-D68, have been associated with acute flaccid myelitis (AFM). Clinical features distinguishing AFM presentations specific EV types are not well described. Methods EV-associated was defined as any child presenting to Children’s Hospital Colorado in 2013–2018 who met the Council of State Territorial Epidemiologists definition for confirmed (flaccid limb weakness longitudinal gray-matter-predominant spinal cord lesion on...
Monday, April 27April 14, 2020Free AccessDevelopment and Evaluation of a Child Neurology Residency Curriculum for Delivering Bad News (2164)Jan Martin, Fiona Horgan, Craig Press, Ricka Messer, Megan Barry, Allison Feldman, Paritosh KaulAuthors Info & AffiliationsApril 2020 issue94 (15_supplement)https://doi.org/10.1212/WNL.94.15_supplement.2164 Letters to the Editor