- Advanced Breast Cancer Therapies
- Gastric Cancer Management and Outcomes
- HER2/EGFR in Cancer Research
- Metastasis and carcinoma case studies
- Cancer Treatment and Pharmacology
- Bariatric Surgery and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Circadian rhythm and melatonin
- CAR-T cell therapy research
- Endoplasmic Reticulum Stress and Disease
- Hepatitis C virus research
- Body Contouring and Surgery
- Recycling and utilization of industrial and municipal waste in materials production
- Cancer Risks and Factors
- Advanced materials and composites
- Extracellular vesicles in disease
- Ion channel regulation and function
- Hepatitis B Virus Studies
- Estrogen and related hormone effects
- Helicobacter pylori-related gastroenterology studies
- Advanced ceramic materials synthesis
- Cancer Immunotherapy and Biomarkers
- Pancreatic function and diabetes
- Breast Cancer Treatment Studies
- Inflammatory Biomarkers in Disease Prognosis
University of Chinese Academy of Sciences
2019-2023
Ningbo No. 2 Hospital
2023
Zhejiang University
2016
Abstract Background The prognostic significance of peripheral blood-derived inflammation markers in patients with gastric cancer (GC) has not been elucidated. This study aimed to investigate the relationship between systemic inflammatory and GC prognosis. Methods A prospective observational cohort involving 598 was conducted analyze prognosis based on markers. following were evaluated: neutrophil-lymphocyte ratio (NLR), platelet lymphocyte (PLR), immune-inflammation index (SII), C-reactive...
The purpose of this research is to investigate the prognostic factors patients with stage I gastric cancer (GC) and determine whether adjuvant chemotherapy improves prognosis for high-risk patients.We performed a retrospective analysis at Sir Run Shaw Hospital, Zhejiang University School Medicine, HwaMei Chinese Academy Sciences from January 2001 December 2015. Cox regression Kaplan-Meier were used evaluate relationship between patients' clinicopathologic characteristics prognosis.A total...
Pathological cardiac hypertrophy (CH) is featured by myocyte enlargement and malfunction. Multiple signaling pathways have been implicated in diverse pathological physiological processes CH. However, the function of LOC102549726/miR-760-3p network CH remains unclear. Here, we characterize functional role delineate underlying mechanism. The expression LncRNA LOC102549726 hypertrophic markers was significantly increased compared to control, while level miR-760-3p decreased. Next, examined ER...
The potassium channel protein KCNH2 is encoded by gene, and there are more than 300 mutations of KCNH2. Unfolded response (UPR) typically initiated in to an accumulation unfolded and/or misfolded proteins the endoplasmic reticulum (ER). present study aimed explore UPR process role activating transcription factor 6 (ATF6) abnormal expression voltage-gated subfamily H member 2 (KCNH2)A561V. wild-type (wt) A561V mutant was constructed with his-tag. 293 cells were used divided into...