Kang Zhang

ORCID: 0000-0002-8521-0247
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Research Areas
  • Cancer, Lipids, and Metabolism
  • Inflammatory Biomarkers in Disease Prognosis
  • Cancer Immunotherapy and Biomarkers
  • Retinal Imaging and Analysis
  • Retinal Diseases and Treatments
  • Lung Cancer Treatments and Mutations
  • Nutrition, Genetics, and Disease
  • Retinal and Optic Conditions
  • Cancer Genomics and Diagnostics
  • Gastric Cancer Management and Outcomes
  • Advanced Radiotherapy Techniques
  • Plant-based Medicinal Research
  • Anesthesia and Neurotoxicity Research
  • Medicinal Plants and Bioactive Compounds
  • Glioma Diagnosis and Treatment
  • Ferroptosis and cancer prognosis
  • Brain Metastases and Treatment
  • Thyroid Cancer Diagnosis and Treatment
  • Prenatal Screening and Diagnostics
  • Genomic variations and chromosomal abnormalities
  • Cardiovascular Disease and Adiposity
  • Traditional Chinese Medicine Studies
  • Pharmacological Effects of Natural Compounds
  • Radiomics and Machine Learning in Medical Imaging
  • interferon and immune responses

China Academy of Chinese Medical Sciences
2025

First Affiliated Hospital of Henan University
2022-2025

United Imaging Healthcare (China)
2023

Guangxi University of Science and Technology
2022

BGI Group (China)
2022

Shaoxing People's Hospital
2021

Shaoxing University
2021

Ningbo University
2020

Jining First People's Hospital
2020

Wuhan University
2020

Abstract Context Various risk factors have been associated with the of thyroid cancer in observational studies. However, causality is not clear given susceptibility confounding and reverse causation. Objective A 2-sample Mendelian randomization approach was used to estimate effect potential on risk. Methods Genetic instruments proxy 55 were identified by genome-wide association studies (GWAS). Associations these genetic variants estimated GWAS FinnGen Study (989 cases 217 803 controls)....

10.1210/clinem/dgac196 article EN The Journal of Clinical Endocrinology & Metabolism 2022-04-02

Abstract Background The prognostic significance of peripheral blood-derived inflammation markers in patients with gastric cancer (GC) has not been elucidated. This study aimed to investigate the relationship between systemic inflammatory and GC prognosis. Methods A prospective observational cohort involving 598 was conducted analyze prognosis based on markers. following were evaluated: neutrophil-lymphocyte ratio (NLR), platelet lymphocyte (PLR), immune-inflammation index (SII), C-reactive...

10.1186/s12893-020-00884-8 article EN cc-by BMC Surgery 2020-10-02

Compared with lobectomy, the anatomical structure of lung segment is relatively complex and easy to occur variation, thus it increases difficulty risk precise segmentectomy. The application three-dimensional computed tomography bronchography angiography (3D-CTBA) combined a printing (3D printing) model can ensure safety operation simplify surgical procedure certain extent. We aimed estimate value 3D-CTBA 3D in thoracoscopic pulmonary segmentectomy.We retrospectively reviewed clinical data 65...

10.21037/jtd-21-16 article EN Journal of Thoracic Disease 2021-02-01

Duodenal stump leakage (DSL) is a potentially fatal complication that can occur after gastrectomy, but its underlying risk factors are unclear. This study aimed to investigate the and management of DSL laparoscopic radical gastrectomy for gastric cancer (GC).Relevant data were collected from several prospective databases retrospectively analyze GC patients who underwent Billroth II (B-II) or Roux-en-Y (R-Y) reconstruction 2 institutions (Sir Run Shaw Hospital, Zhejiang University School...

10.5230/jgc.2020.20.e4 article EN cc-by-nc Journal of the Korean Gastric Cancer Association 2020-01-01

Objective Patients with non-small-cell lung cancer (NSCLC) and primary or acquired resistance do not respond to targeted drugs. We explored whether cells can be cultured from liquid biopsies patients tyrosine kinase inhibitors (TKIs). aimed predict patients’ responses drugs according in vitro drug testing results. Methods Cancer cell cultures were established the pleural effusion of a patient TKI-resistant NSCLC using conditional reprogramming technique. Phenotypic sensitivity tests...

10.1177/0300060520955058 article EN cc-by-nc Journal of International Medical Research 2020-09-01

Abstract Background and objective: The prognostic significance of peripheral blood-derived inflammation markers in patients with gastric cancer (GC) has not been elucidated. This study aimed to investigate the relationship between systemic inflammatory GC prognosis. Methods: A prospective observational cohort involving 598 was conducted analyze prognosis based on markers. following were evaluated: neutrophil-lymphocyte ratio (NLR), platelet lymphocyte (PLR), immune-inflammation index (SII),...

10.21203/rs.3.rs-40554/v1 preprint EN cc-by Research Square (Research Square) 2020-07-08

8541 Background: Programmed death-ligand 1 (PD-L1) serves as a major predictive biomarker for immune checkpoint inhibitors in non-small cell lung cancer (NSCLC). However, the relationship between PD-L1 expression and genetic features of NSCLC remains unclear. The aim this study was to explore correlation profiles NSCLC. Methods: FFPE tumor matched blood samples from 568 (487 adenocarcinomas (ACAs) 81 squamous carcinomas (SCAs)) patients were collected NGS-based targeted panel sequencing....

10.1200/jco.2019.37.15_suppl.8541 article EN Journal of Clinical Oncology 2019-05-20

Objective To systematically review the effect of exercise on body composition simple obesity in China.
 Methods We electronically searched databases including CNKI、VIP、WanFang Data、PubMed、Medline、Web Science to collect studies therapy for from inception June 2016. Two reviewers independently screened literature, extracted data and assessed risk bias included studies. Then, meta-analysis was performed by using RevMan 5.3 software.
 Results A total 17 papers involving 627 patients...

10.14428/ebr.v1i3.9003 article EN cc-by Exercise Biochemistry Review 2018-10-03

背景植物病原真菌丝裂原活化蛋白激酶(Mitogen-activated protein kinase,MAPK)信号途径参与病菌有性生殖、细胞壁完整、菌丝侵染、致病力、胁迫响应等过程,灰葡萄孢MAPK信号途径参与病菌生长发育、致病力以及胁迫响应,但MAPK信号途径基因在灰葡萄孢中的功能尚未完全阐明,该信号途径对灰葡萄孢的生长发育和致病力的调控机制尚不明确。 目的明确灰葡萄孢MAPK编码基因bmp1、bmp3在病菌生长发育、致病力以及氧化胁迫响应过程的功能,为进一步阐明MAPK信号途径调控灰葡萄孢生长发育和致病力的分子机制奠定基础。 方法利用RNAi技术构建灰葡萄孢MAPK编码基因bmp1和bmp3的RNAi突变体,并以野生型BC22菌株为对照,对bmp1和bmp3基因的RNAi突变体的表型、致病力以及对氧化胁迫的敏感性进行分析。...

10.13344/j.microbiol.china.180503 article ZH-CN 2019-02-20

Objective To evaluate the application of bilateral thoracic paravertebral block (bTPVB) combined with general anesthesia in thoracoscopic-laparoscopic esophagectomy (TLE) and its effects on early postoperative recovery. Methods Seventy patients esophageal cancer scheduled for TLE were divided into two groups according to random number table method (n=35): a group (group G) bTPVB B). Five excluded due intraoperative blood transfusion, traditional open surgery or other reasons. Finally,...

10.3760/cma.j.issn.1673-4378.2020.02.012 article EN 2020-02-15

In the modern middle and long distance running training, endurance quality training is a very important content. Strengthening of runners can not only improve effect special technical but also willpower athletes, such as perseverance never give up. This paper first briefly introduces significance for runners, then analyzes methods runners. The purpose this study to understanding coaches middle-distance on provide some references carry out scientifically.

10.25236/fer.2020.031309 article EN Frontiers in Educational Research 2020-12-21

Abstract Background: The prognostic significance of peripheral blood-derived inflammation markers in patients with gastric cancer (GC) has not been elucidated. This study aimed to investigate the relationship between systemic inflammatory and GC prognosis. Methods: A prospective observational cohort involving 598 was conducted analyze prognosis based on markers. following were evaluated: neutrophil-lymphocyte ratio (NLR), platelet lymphocyte (PLR), immune-inflammation index (SII), C-reactive...

10.21203/rs.3.rs-40554/v2 preprint EN cc-by Research Square (Research Square) 2020-09-04

Abstract Background and objective: The prognostic significance of peripheral blood-derived inflammation markers in patients with gastric cancer (GC) has not been elucidated. This study aimed to investigate the relationship between systemic inflammatory GC prognosis. Methods: A prospective observational cohort involving 598 was conducted analyze prognosis based on markers. following were evaluated: neutrophil-lymphocyte ratio (NLR), platelet lymphocyte (PLR), immune-inflammation index (SII),...

10.21203/rs.3.rs-21459/v1 preprint EN cc-by Research Square (Research Square) 2020-04-12

Abstract Background: The prognostic significance of peripheral blood-derived inflammation markers in patients with gastric cancer (GC) has not been elucidated. This study aimed to investigate the relationship between systemic inflammatory and GC prognosis. Methods: A prospective observational cohort involving 598 was conducted analyze prognosis based on markers. following were evaluated: neutrophil-lymphocyte ratio (NLR), platelet lymphocyte (PLR), immune-inflammation index (SII), C-reactive...

10.21203/rs.3.rs-40554/v3 preprint EN cc-by Research Square (Research Square) 2020-09-24
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