- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metal complexes synthesis and properties
- Catalytic Cross-Coupling Reactions
- Electrochemical Analysis and Applications
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Asymmetric Hydrogenation and Catalysis
- Inorganic and Organometallic Chemistry
- Crystallography and molecular interactions
- Organometallic Complex Synthesis and Catalysis
- Radiation Effects and Dosimetry
- Molecular Sensors and Ion Detection
- Synthesis and Biological Evaluation
- Catalytic C–H Functionalization Methods
- Free Radicals and Antioxidants
- Bone Tissue Engineering Materials
- Proteins in Food Systems
- Microplastics and Plastic Pollution
- Nanoparticles: synthesis and applications
- Quinazolinone synthesis and applications
- Recycling and Waste Management Techniques
- Microencapsulation and Drying Processes
- Neuroscience and Neuropharmacology Research
- Organoboron and organosilicon chemistry
- Computational Drug Discovery Methods
Ege University
1997-2024
Institute of Social Sciences
2024
Gazi University
2010
Samsun University
2003-2004
Ondokuz Mayıs University
1991-2002
A series of nitrile-modified N-heterocyclic carbene (NHC) complexes Ir(III) (2a–e) and Ru(II) (3a–d) have been prepared by transmetallation [IrCp*Cl2]2 [RuCl2(p-cymene)]2 forming an in situ NHC–Ag complex. The structures all were characterized 1H NMR, 13C Fourier transform infrared (FT-IR) spectroscopies. And the clearly elucidated performing X-ray diffraction studies on 2b, 3a, 3c single crystals. NHC–Ir(III) NHC–Ru(II) investigated N-alkylation reaction aniline derivatives with benzyl...
Through the strategy of water soluble N‐heterocyclic carbene (NHC) ligand, Pd‐catalyzed reactions were developed in aqueous media. Therefore, four new piperidoimidazolinium salts ( 1a‐d ) consisting sulfonate a ), esther b , c and carboxylic acid d functionalities their water‐soluble Pd‐NHC complexes 2a ‐ synthesized. The compounds characterized by elemental analysis, FTIR, TGA, UV–vis NMR spectroscopy. catalytic activities investigated using Suzuki‐Miyaura (S‐M) reaction reduction...
It is possible to reveal the potential of water-insoluble drugs by increasing their solubility in water with some nanotechnology techniques. Nanosuspension technology can solve this problem and as well bioavailability these drugs. The present work pointed at evaluation nanosuspension curcumin, a poorly water-soluble drug. Curcumin nanoparticules (CNs) were prepared ultrasonnication method using dichloromethane solvent antisolvent characterized via spectroscopic methods (UV–vis FT-IR)...
The size distributions of microcapsules are important in determining the surface area over which contents released. distribution is generally not normal arournd mean, but biased toward smaller capsule sizes, forming a mode around some characteristic diameter. In order to assess factors effective this drop size, analyses were carried out photographically at each stage complex coacervation process. addition, emulsion investigated as function stirring rate, time and phase ratio. results agreed...
A series of piperidoimidazolinium salts which differ in the chain lengths (butyl, octyl, dodecyl, octadecyl) and their Pd–N‐heterocyclic carbene complexes with pyridine were synthesized characterized using elemental analysis spectroscopic methods. The effects these ligands on catalyst activation performance studied Suzuki–Miyaura reactions arylboronic acid aryl chlorides. complex ligand having longest length was found to be most active. results demonstrated that alkyl...
Application of N-heterocyclic carbene (NHC) palladium complexes has been successful for the modulation C-C coupling reactions. For this purpose, a series azolium salts (1a-f) including benzothiazolium, benzimidazolium, and imidazolium, bearing CN-substituted benzyl moiety, their (NHC)2PdBr2 (2a-c) PEPPSI-type (3b-f) have systematically prepared to catalyse acylative Suzuki-Miyaura reaction acyl chlorides with arylboronic acids form benzophenone derivatives in presence potassium carbonate as...
Abstract This study focuses on the cytotoxic effect properties of 4‐aryl‐functionalized benzo[ d,e ]benzo[4,5]imidazo[2,1‐ a ]isoquinolin‐7‐one ( 4‐X−Ar−BBI ). The electron‐withdrawing and electron‐donating substituents located at para position phenyl ring attached to heterocyclic structure have altered pi electron density within structure. change in has influenced intercalation ability impacted intensity its interaction with DNA. 4‐aryl‐benzo[ derivatives ) were prepared via Suzuki–Miyaura...
Application of palladium complexes in sp2-sp2 carbon-carbon bond formation reactions has been successful. For this purpose, the study, complex carrying histamine moiety was systematically prepared to catalyze Suzuki-Miyaura cross coupling reaction bromobenzene with arylboronic acids form biaryls presence NaOH as base. All synthesized compound and were fully characterized by Fourier Transform Infrared (FTIR) 1H- 13C-NMR spectroscopies. As a result investigation optimum conditions for...