A5015557551- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Radiation Therapy and Dosimetry
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Hepatocellular Carcinoma Treatment and Prognosis
- Head and Neck Cancer Studies
- Advanced X-ray and CT Imaging
- Ultrasound and Hyperthermia Applications
- Breast Cancer Treatment Studies
- Management of metastatic bone disease
- Lanthanide and Transition Metal Complexes
- Cardiac Arrhythmias and Treatments
- Brain Metastases and Treatment
- Brain Tumor Detection and Classification
- Artificial Intelligence in Healthcare and Education
- Atomic and Subatomic Physics Research
- Glioma Diagnosis and Treatment
- Advances in Oncology and Radiotherapy
- Radioactivity and Radon Measurements
- Nuclear Physics and Applications
- Graphite, nuclear technology, radiation studies
Sorbonne Université
2018-2024
Hôpital Charles-Foix
2024
Université Paris-Saclay
2018-2023
Assistance Publique – Hôpitaux de Paris
2018-2023
Hôpital Tenon
2018-2023
Public Health Institute of the Republic of Srpska
2008
Background: Mobility of lung tumors is induced by respiration and causes inadequate dose coverage. Objective: This study quantified tumor motion, velocity, stability for small (≤5 cm) large (>5 to adapt radiation therapy techniques cancer patients.Material Methods: In this retrospective study, 70 patients with were included that 50 20 had a gross volume (GTV). To quantify the motion velocity in upper lobe (UL) lower (LL) central region (CR) peripheral (PR), GTV was contoured all ten...
This study compared phase-gated and amplitude-gated dose deliveries to the moving gross tumor volume (GTV) in lung stereotactic body radiation therapy (SBRT) using Gafchromic External Beam Therapy (EBT3) dosimetry film.Eighty treatment plans two techniques (40 phase gated 40 amplitude gated) were delivered dynamic conformal arc (DCAT). The GTV motion, breathing amplitude, period taken from SBRT patients who performed regular breathing. These parameters re-simulated a modified Varian mini...
Abstract BACKGROUND Predicting progression-free survival (PFS) in glioblastoma (GB) is crucial for post-surgery treatment decisions. Detecting post-operative volumes via pre-radiotherapy (preRT) MRI, combined with clinical and molecular data, improves prognosis. A decision tree model using these features provides valuable insights into PFS when aligned the new RANO resection categories. MATERIAL AND METHODS We analyzed retrospective data from 205 GB treated by STUPP protocol across three...
Background/Aim. For patients with left-sided breast cancer, a major concern is the dose of radiation delivered to heart, because increased risk exposure and consequently coronary events side effects. In order reduce heart during irradiation, deep inspiration breath-hold (DIBH) technique was implemented in our institution. The aim this retrospective study compare dosimetric parameters DIBH on left anterior descending artery (LAD) ipsilateral lung (IL), compared free breathing (FB) technique....
Purpose: To evaluate internal (lung, heart and diaphragm) external (nine glass marbles) marker motion in correlation with lung tumor motion, to determine potential surrogate for respiratory gating radiation therapy (RGRT) depending on localization, upper lobe (UL) vs lower (LL).Methods: This study included 58 patients (34 male 24 female) small cancer (≤ 5cm), who underwent Stereotactic Body Radiation Therapy (SBRT). All were scanned contoured all ten phases (Varian Eclipse 13.7) after...
Abstract BACKGROUND High-grade gliomas are the most common type of primary brain tumor in adult patients. Despite a multimodal treatment, prognosis remains poor. Accurate stratification survival is crucial for choosing best course therapy. The objective this study was to use radiomics analysis based on multiparametric MRI combined with clinical data high-grade patients incomplete resection identify predictive signature according their overall survival. MATERIAL AND METHODS In multicentric...
Background To evaluate the impact of planning target volume (PTV) density on treatment for lung Stereotactic Body Radiation Therapy (SBRT).Material and methods The PTV coverage was analyzed in two groups 40 SBRT patients. One group had <0.5 g/cm3, while other >0.5 g/cm3. treatments were planned Pinnacle 9.10, using collapsed cone convolution (CCC) algorithm. prescribed dose 60 Gy to 4–8 fractions. Respecting constraint (D98% > 95%), we compared changes isodose line prescription, number...
Abstract Purpose: To evaluate the breathing amplitude, tumor motion, patient positioning, and treatment volumes among consecutive four-dimensional computed tomography (4D-CT) scans, during simulation for lung stereotactic body radiation therapy (SBRT). Material methods: The variation shape of were evaluated 55 cancer patients after 4D-CT acquisitions, scanned at one-week intervals. impact in amplitude on motion was determined 20 patients. gross volume (GTV) contoured from a free-breathing CT...
Background The aim of this study is to compare the dose delivered organs at risk (OAR), using static beams (SF) and a dynamic conformational arc (DCA) with flattening filter free (FFF) beams, for lung stereotactic body radiation therapy (SBRT).Methods 100 patients cancer were treated SBRT, FF (TrueBeam STx, 6 MV, IQ = 0.67, 600 MU/min), separated into two groups: DCA (50 patients) SF patients). These retrospectively re-planned 6XFFF 0.63, 1400 MU/min. beam-on time dosimetric gain on planning...
Background: The use of imaging is indispensable in modern radiation therapy, both for simulation and treatment delivery. For safe sure utilization, dose delivery from must be evaluated. Objective: This study aims to investigate the organ at risk (OAR) delivered by during lung stereotactic body therapy (SBRT) evaluate its contribution total dose.Material Methods: In this retrospectively study, organs (OARs) (spinal cord, esophagus, lungs, heart) effective were evaluated 100 consecutive...
Abstract BACKGROUND The aim of our multi-centric study is to evaluate the predictive relapse factors for high-grade glioma patients. MATERIAL AND METHODS We studied retrospectively cohort patients, from 2009 2021 at three French medical centers. This data collection was carried out as part national funding promote integration AI tools into clinical oncology routine (AI.DReAM project). Clinical, pathological, genomic, and radiotherapy data, with MR images before treatment relapse, were...
Introduction: Gated tangential field-in-field (FIF) technique is used to lower the dose organs at risk for breast cancer radiotherapy (RT). In this study, authors investigated accuracy of delivered treatment plan with and without gating using a two-dimensional detector array patient-specific verification purposes.Methods: 6MV beams were merged FIF RT (forward Intensity Modulated Radiation Therapy). The respiration signals gated delivery obtained from one-dimensional moving phantom real-time...