Rose Mara Ortega

ORCID: 0000-0003-1391-7857
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About
Contact & Profiles
Research Areas
  • Oral and Maxillofacial Pathology
  • Salivary Gland Tumors Diagnosis and Treatment
  • Oral Health Pathology and Treatment
  • Tumors and Oncological Cases
  • Cancer, Lipids, and Metabolism
  • Sarcoma Diagnosis and Treatment
  • Oral health in cancer treatment
  • Autoimmune Bullous Skin Diseases
  • Head and Neck Cancer Studies
  • Soft tissue tumor case studies
  • HIV/AIDS oral health manifestations
  • Fungal Infections and Studies
  • Peroxisome Proliferator-Activated Receptors
  • Ear and Head Tumors
  • Oral and gingival health research
  • Urticaria and Related Conditions
  • dental development and anomalies
  • Bone Tumor Diagnosis and Treatments
  • Viral-associated cancers and disorders
  • Histiocytic Disorders and Treatments
  • Cancer-related Molecular Pathways
  • Antifungal resistance and susceptibility
  • Cancer and Skin Lesions
  • Vascular Tumors and Angiosarcomas
  • Bone and Dental Protein Studies

Universidade Federal de Juiz de Fora
2018-2024

Fundação Faculdade de Odontologia
2015-2024

Empresa de Desenvolvimento Mineiro (Portugal)
2023

Universidade Estadual Paulista (Unesp)
2015-2017

Universidade Paulista
2017

Universidade Estadual de Campinas (UNICAMP)
2013-2014

Oulu University Hospital
2013

Universidade Federal do Rio de Janeiro
2013

University of Oulu
2013

University of Helsinki
2013

Fatty acid synthase (FASN) is the biosynthetic enzyme responsible for endogenous synthesis of fatty acids. It downregulated in most normal cells, except lipogenic tissues such as liver, lactating breast, fetal lung, and adipose tissue. Conversely, several human cancers, including head neck squamous cell carcinomas (HNSCC), overexpress FASN, which has been associated with poor prognosis recently suggested a metabolic oncoprotein. Orlistat an irreversible inhibitor FASN activity cytotoxic...

10.1158/1535-7163.mct-12-1136 article EN Molecular Cancer Therapeutics 2013-12-21

The metabolic enzyme fatty acid synthase (FASN) is responsible for the endogenous synthesis of palmitate, a saturated long-chain acid. In contrast to most normal tissues, variety human cancers overexpress FASN. One such cancer cutaneous melanoma, in which level FASN expression associated with tumor invasion and poor prognosis. We previously reported that two inhibitors, cerulenin orlistat, induce apoptosis B16-F10 mouse melanoma cells via intrinsic pathway. Here, we investigated effects...

10.1371/journal.pone.0101060 article EN cc-by PLoS ONE 2014-06-25

Os cigarros eletrônicos surgiram na China em 2003 como uma opção para a cessação do tabagismo. Atualmente o seu uso é crescente entre adolescentes e adultos jovens, sendo que os efeitos cigarro eletrônico saúde bucal são pouco conhecidos. O objetivo desse estudo foi realizar revisão crítica atualizada sobre composição dos eletrônicos, estrutura dispositivos bucal. Foi realizada busca por artigos científicos nas bases de dados PubMed (Medline), Scopus Periódicos Capes, utilizando termos:...

10.34119/bjhrv7n2-136 article PT Brazilian Journal of Health Review 2024-03-15

Introdução: O câncer bucal é apontado como um problema de saúde relevante e apresenta alta taxa incidência mortalidade. consumo tabaco álcool são considerados os principais fatores risco para sua ocorrência. Apesar dos avanços relacionados a detecção, diagnóstico tratamento, grande parte pacientes ainda diagnosticada com doença em estágio avançado. Objetivo: Estabelecer associados ao atraso no do bucal. Material Métodos: Foram pesquisados artigos nas bases dados MEDLINE/PubMed, SciELO...

10.34019/1982-8047.2023.v49.39514 article PT cc-by HU Revista 2024-01-04

Ecstasy is an illicit drug that has been increasingly abused by young people. This synthetic both stimulant and hallucinogenic effects usually consumed in a tablet. The side of ecstasy use include nausea, muscle cramping, fever, symptoms mostly linked to muscular tension including jaw pain, facial headaches. There are few studies assessing the on oral mucosa, clinically histopathologically. authors report 2 women (22- 27-year-old) who presented multifocal erosions ulcerations. lesions were...

10.1097/scs.0000000000005033 article EN Journal of Craniofacial Surgery 2019-03-19

De acordo com a Organização Mundial da Saúde (OMS) o papilomavírus humano (HPV) foi considerado como um importante fator no desenvolvimento do carcinoma espinocelular orofaringe em todo mundo. Além disso, 8ª Edição American Joint Committee on Cancer (AJCC) reconheceu os tumores HPV-positivos e HVP-negativos entidades distintas. O objetivo presente estudo realizar uma revisão de literatura sobre as características clínicas histopatológicas na região HPV-positivos, caracterizando perfil dos...

10.34119/bjhrv7n1-030 article PT Brazilian Journal of Health Review 2024-01-09

INTRODUCTION: The presence of a foreign body (any object or structure that is outside its ideal location) should be considered in any head and neck injury. Foreign bodies can remain dormant soft tissues for years without causing damage, however, their induce complex acute chronic inflammatory reaction the type, which results symptoms patient. For correct diagnosis treatment plan, detailed clinical examination combined with imaging tests necessary. OBJECTIVE: aim this study was to report case...

10.56238/homeivsevenhealth-024 article EN 2024-06-07

Introdução: A queilite actínica (QA) é considerada um distúrbio oral potencialmente maligno que pode evoluir para o carcinoma espinocelular de lábio. Acomete mais pacientes do sexo masculino e pessoas pele clara exercem atividades ao sol. Objetivo: O presente estudo objetivou caracterizar a prevalência perfil dos acometidos com QA na cidade Governador Valadares – MG. Métodos: Foram acessados 301 prontuários atendidos no serviço Estomatologia da Universidade Federal Juiz Fora Campus...

10.34119/bjhrv7n4-460 article PT Brazilian Journal of Health Review 2024-08-29

Aim: The aim of this study is to report two cases postsurgical ciliated cysts (PSCC) in patients from Brazil with a history trauma the maxillary zygomatic suture region and traumatic tooth extraction. Additionally, we conducted literature review PSCC. Methods: We reported clinical edentulous diagnosed PSCC, including information on medical surgical history. Furthermore, performed review, identifying previous PSCC compiling relevant information. Results: In Case 1, patient, 64-year-old...

10.20396/bjos.v23i00.8674880 article EN cc-by Brazilian journal of oral sciences/Brazilian Journal of Oral Sciences 2024-10-16

RESUMO Os defeitos de desenvolvimento esmalte são alterações resultantes distúrbios no processo da amelogênese, podendo envolver fatores genéticos, sistêmicos, locais ou ambientais. que desencadeiam os estão relacionados principalmente a injúrias durante o estrutura dental. Na dentição decídua, traumas e/ou consumo medicamentos gestação podem estar envolvidos. permanente eventos traumáticos lesões cárie nos correspondentes decíduos fortemente associados. O objetivo do presente estudo foi...

10.1590/1981-86372024004720240052 article PT cc-by RGO - Revista Gaúcha de Odontologia 2024-01-01

This study aimed to assess the prevalence of oral lesions in patients living with HIV infection and their association CD4 count, viral load, antiretroviral therapy HIV.A cross-sectional was conducted on a sample 161 attending the… All were examined for lesions, current counts, type, duration therapy. Data analyses carried out using Chi-Square, Student T/Mann-Whitney, logistic regression tests.Oral observed 58.39% HIV. Periodontal disease 78 (48.45%) or without mobility 79 (49.07%) more...

10.1016/j.bjorl.2023.01.001 article EN cc-by Brazilian Journal of Otorhinolaryngology 2023-01-23

Achterberg J, Duquiane L, Huebbe M, Williams C. PowerPoint presentation handouts and college student learning outcomes. Int J Scholarship Teaching Learning. 2007;1(1):1-13. The use of Microsoft slides has become increasingly prevalent in educational settings. It been proposed that using may decrease students' need for notetaking provide more opportunity to listen engage classroom discussion. However, some have suggested detract from by promoting “absence” lack attention. With respect styles,...

10.1097/00001416-200801000-00012 article EN Journal of Physical Therapy Education 2008-01-01
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