A5008632090- Reproductive Biology and Fertility
- Luminescence Properties of Advanced Materials
- Medical Imaging Techniques and Applications
- Atomic and Subatomic Physics Research
- Tissue Engineering and Regenerative Medicine
- Renal and related cancers
- Lanthanide and Transition Metal Complexes
- Seed Germination and Physiology
- Microfluidic and Capillary Electrophoresis Applications
- Advanced X-ray and CT Imaging
- Innovative Microfluidic and Catalytic Techniques Innovation
- Nuclear Physics and Applications
- Urological Disorders and Treatments
- Radiation Detection and Scintillator Technologies
- Inorganic Fluorides and Related Compounds
- Nanoplatforms for cancer theranostics
- Digital Radiography and Breast Imaging
- Luminescence and Fluorescent Materials
- Organ Transplantation Techniques and Outcomes
- Ovarian function and disorders
- Sperm and Testicular Function
- Ultrasound and Hyperthermia Applications
- Photoacoustic and Ultrasonic Imaging
- Freezing and Crystallization Processes
- Magnetic and Electromagnetic Effects
Junta de Andalucía
2017-2021
Centro Nacional de Aceleradores
2017-2021
Universidad de Sevilla
2010-2021
Consejo Superior de Investigaciones Científicas
2019
IVI Sevilla Clinic
2018
Trinity College Dublin
2010
Abstract The advantage of stepped vitrification (SV) is avoiding ice crystal nucleation, while decreasing the toxic effects high cryoprotectant concentrations. We aimed to test this method for human ovarian tissue cryopreservation. Ovarian cortex was taken from 7 fertile adult women. Samples were subjected an SV protocol performed in automatic freezer, which allowed sample transfer ever higher concentrations dimethyl sulfoxide (DMSO) as temperature reduced. Histological evaluation...
Abstract The Cu I ‐catalysed Huisgen cycloaddition “click” reaction has been applied to the synthesis of a range triazole‐linked glycoporphyrins. under microwave‐heating conditions shown provide general and robust methodology for mono‐, di‐, tri‐ tetra‐modified A sequential “double‐click” process was employed access new class bis‐modified 5,10‐diglycoporphyrins displaying heterogeneous carbohydrates.
Bi3+ codoping has been proposed in this work with a twofold objective, namely, enhancing the luminescence emission of Eu3+:LaF3 nanoparticles (NPs) and increasing their X-ray attenuation capacity, purpose obtaining bimodal bioprobe for bioimaging computed tomography. The synthesis method, reported here first time LaF3 particles, allowed uniform, nonaggregated NPs using homogeneous precipitation polyol medium at room temperature just 2 h. simplicity method allows large-scale production NPs....
Uniform Nd3+-doped LuVO4 nanophosphors have been synthesized for the first time in literature by using a poliol-based method at 120 °C from Nd3+ and vanadate precursors. After optimizing Nd doping level, these phosphors present intense luminescence near-infrared biological windows. The X-ray attenuation capacity of optimum nanophosphor has found to be higher than that commercial computed tomography contrast agent. surface coating with polyacrylic acid, such nanoparticles high colloidal...
This paper presents an integrated preconcentration cartridge for [ <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">18</sup> F]Fluoride radiochemistry in a polydimethylsiloxane (PDMS) disposable chip. The fabrication process the chip is designed to allow construction of final device full synthesis F]fludeoxyglucose, one standard radiopharmaceuticals used positron-emission tomography imaging. first step that and composed two phases: 1) retention;...
Silicon photomultipliers (SiPM) can be used to sense the position and movement of radioactive reagents involved in synthesis radiopharmaceuticals, while providing information on evolution through different steps this synthesis. An SiPM array placed next a lab-on-chip substrate made PDMS is able detect particles emitted by <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">18</sup> F, radioisotope fluorine-based positron-emission tomography (PET)...
A new room-temperature method has been developed that yields, for the first time in literature, uniform and well-dispersed CaWO4 nanospindles. This is based on use of microemulsions consisting aqueous solutions Ca2+ WO42– precursors, cyclohexane as organic medium, Triton X-100 surfactant, n-octanol cosurfactant. We show formation nanospindles requires a restrictive set experimental conditions. These particles crystallize into tetragonal phase emit blue–green luminescence when excited by UV...
Due to the high atomic number of lutetium and low phonon energy fluoride matrix, Lu-based nanoparticles doped with active lanthanide ions are potential candidates as bioprobes in both X-ray computed tomography luminescent imaging. This paper shows a method for fabrication uniform, water-dispersible Eu3+:(H3O)Lu3F10 different Eu contents. Their properties were studied by means excitation emission spectra well decay curves. The attenuation capacity phosphor showing highest intensity was...
The synthesis of uniform neodymium-doped lanthanum trifluoride nanoparticles with lenticular shape and a mean diameter around 45 nm by using homogeneous precipitation method is reported. luminescent properties the synthesized samples in terms their emission spectra lifetime are analyzed as function Nd content to find optimum phosphor its suitability for imaging second biological window. X-ray attenuation evaluated investigate additional ability contrast agent computed tomography. Finally,...
One of the main problems in cryopreservation biological samples is formation ice and consequent mechanical damage to cells tissues, due crystalline structure its associated damage. It necessary detect this deleterious ice, especially tissues organs, because their large volume complexity vascular system case bulky organs. In work, we propose use X-ray Computed Tomography (CT) inside To achieve aim, rabbit kidneys were loaded with cryoprotectant solutions containing Me2SO at low temperatures...
Microfluidic techniques have demonstrated an important impact on radiochemical reactions for Positron Emission Tomography (PET), due to smaller reaction times and precursor quantities. An integrated retention elution cartridge in a PDMS chip is presented, experimental results that confirm its operation are provided. It intended preconcentrate [18F]Fions microfluidic system produce radiopharmacy drugs PET imaging. Pre-concentration subsequent drying of I18FIFions the first step radiotracer...
Uniform Ba0.18Ce0.82F2.82 nanospheres have been obtained after aging a solution of barium and cerium nitrates sodium tetrafluoroborate in mixture ethylene glycol water at 120 °C for 20 hours. The diameter the spheres could be tailored from 65 nm to 80 by varying NaBF4 concentration while maintaining their colloidal stability aqueous suspension. Increasing temperature led phase transformation hexagonal cubic symmetry concomitant increase Ba/Ce ratio, which reached value close nominal one...