Fernanda Paulini

ORCID: 0000-0003-4490-9614
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About
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Research Areas
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Sperm and Testicular Function
  • Genetic and phenotypic traits in livestock
  • Animal Genetics and Reproduction
  • Renal and related cancers
  • Tissue Engineering and Regenerative Medicine
  • Genetics and Plant Breeding
  • Reproductive Physiology in Livestock
  • Science and Education Research
  • Seaweed-derived Bioactive Compounds
  • Rural Development and Agriculture
  • Effects of Environmental Stressors on Livestock
  • Gender, Sexuality, and Education
  • Nanoparticles: synthesis and applications
  • Livestock Management and Performance Improvement
  • Religion and Society in Latin America
  • Assisted Reproductive Technology and Twin Pregnancy
  • Family Dynamics and Relationships
  • Hormonal and reproductive studies
  • Growth Hormone and Insulin-like Growth Factors
  • Graphene and Nanomaterials Applications
  • Optimal Experimental Design Methods
  • TGF-β signaling in diseases
  • Phytoestrogen effects and research

Universidade de Brasília
2012-2024

UCLouvain
2015-2018

Brazilian Agricultural Research Corporation
2010

STUDY QUESTIONDo primordial-primary versus secondary follicles embedded inside a fibrin matrix have different capabilities to survive and grow after isolation transplantation?

10.1093/humrep/dev299 article EN Human Reproduction 2015-11-30

Even though sheep embryo cryopreservation is a commonly used procedure the survival and pregnancy outcomes can vary greatly. This study investigated whether was causing subtle changes in ultrastructure, mitochondrial activity or cytoskeletal integrity. Sheep embryos were either slow cooled 1.5 M EG (n = 22), vitrified 20% + DMSO with 0.5 sucrose Open Pulled Straws (OPS) 24). One hour after warming cryopreserved differed from control that they had no combined disorganization large vesicles....

10.1016/j.cryobiol.2013.05.012 article EN publisher-specific-oa Cryobiology 2013-06-12

This study evaluates the post-hatching development of in vitro-produced (IVP) embryos until Day 14. On 7, IVP were either transferred to recipient uteruses or placed a (PHD) system. As control group, vivo-produced (IVV), Day-7 also uteruses. All groups collected on 14 and morphologically evaluated. Day-14 IVV used for quantification eight genes (PLAC8, CD9, SLC2A1, SLC2A3, KRT8, SOD2, HSP1A1, IFNT2) by reverse transcriptase qPCR. from PHD system smaller (2.92 ± 0.45 mm) had lower embryonic...

10.1002/mrd.22230 article EN Molecular Reproduction and Development 2013-08-19

Components of (co)variance and genetic parameters were estimated for adjusted weights at ages 120 (W120), 240 (W240), 365 (W365) 450 (W450) days Polled Nellore cattle raised on pasture born between 1987 2010. Analyses performed using an animal model, considering fixed effects: herd-year-season birth calf sex as contemporary groups the age cow a covariate. Gibbs Samplers used to estimate components, additive effects, which accounted great proportion total variation in these traits. High...

10.1371/journal.pone.0075423 article EN cc-by PLoS ONE 2013-09-10

Are mouse preantral follicles differently affected by isolation, encapsulation and/or grafting procedures according to stage?Isolated secondary showed superior ability survive and grow after transplantation, which was not related a particular effect of the isolation procedure, but rather their own induce neoangiogenesis.Isolated encapsulated can (6-27%) (80-100%) in fibrin matrix with low concentration fibrinogen thrombin (F12.5/T1) short-term transplantation.An vivo experimental model using...

10.1093/molehr/gax016 article EN Molecular Human Reproduction 2017-03-13

Magnetic nanoparticles can be used in different areas of biology. It is therefore important to know the effects such nanomaterials on germline cells as they may traverse blood-testis barrier. This work aimed evaluate response bull sperm after exposure a magnetic fluid containing DMSA-coated maghemite (MNP-DMSA) order determine nanotoxicity. Bull was incubated with MNP-DMSA at final concentrations 0.06, 0.03 or 0.015 mg Fe/mL. Sperm kinetics, plasma membrane integrity and acrosome reaction...

10.1080/02656736.2017.1341646 article EN International Journal of Hyperthermia 2017-06-13

The aim of this study was to define the population, morphological and ultrastructural characteristics bitch preantral follicles (PAFs) compare effects on morphology PAF two cryopreservation techniques - slow freezing (SF) vitrification (V) bitches' ovarian tissue. average population (number per ovary) PAFs 48,541 ± 18,366, where 94.25% were primordial (45,145 16,076). diameter 27.5 4.2 μm. overall percentage morphologically normal 93.66 6.81% for control group, 86.16 11.05% after SF 68.14...

10.1016/j.cryobiol.2018.02.013 article EN publisher-specific-oa Cryobiology 2018-02-23

Abstract Cryopreservation of ovarian tissue followed by transplantation represents a strategy to restore function and fertility. Stress from cryopreservation-thawing processes can lead alterations and/or damage mitochondrial structure functionality. High resolution respirometry histological analysis were used evaluate the effect cryopreservation on tissue. Four different conditions performed: Fresh non-transplanted tissue, transplanted Cryopreserved All groups able respond...

10.1038/s41598-021-01082-z article EN cc-by Scientific Reports 2021-11-02

Granulosa cells (GCs) play important roles in the regulation of ovarian functions, and vitro culture is a relevant model for study steroidogenesis follicles. Thus, growth factors secreted by oocyte, like Growth Differentiation Factor 9 (GDF9) Bone Morphogenetic Protein 15 (BMP15), an part luteinization granulosa cells. The aim this work was to express GDF9 BMP15 genes bovine GCs evaluate their effects on process. Samples medium transfected with were obtained 21 consecutive days analyse...

10.1111/rda.13923 article EN Reproduction in Domestic Animals 2021-03-08

This work presents a long-term follow-up (300 days) of rats after single intravenous injection DMSA-coated magnetite nanoparticles (DMSA-MNP). The animals were systematically evaluated by hematological, biochemical, and ultrasound examinations, monitoring the same animal over time. In addition, oxidative stress evaluation, DMSA-MNP biodistribution, computerized tomography for ex vivo organs, histopathology analysis performed at end experiment period. Overall, administration did not cause...

10.3390/nano12193513 article EN cc-by Nanomaterials 2022-10-08

This study was carried out to estimate (co)variance components and genetic parameters for live weight of Nellore cattle from Performance Test Young Bulls using random regression models. Data weights ages 925 weaned males used. The animal model included the fixed effect contemporary group, age at weighing as a covariate effects it considered additive permanent environment animal. residue modeled considering four classes variances. models were compared based on Bayesian information criteria...

10.1186/2193-1801-1-49 article EN SpringerPlus 2012-11-20

As discussões sobre educação sexual ainda têm sido uma área negligenciada nas escolas, devido à falta de preparo dos professores na formação inicial e continuada para lidar com um tema considerado polêmico, visto por muitos como tabu. Neste contexto, o presente estudo teve objetivo analisar a relevância curso em do ensino médio. A pesquisa tem natureza quali-quantitativa. Desse modo, compreender percepção Ensino Médio Distrito Federal acerca da importância sexual, utilizou ofertado pela UnB...

10.12957/redoc.2023.68406 article PT Revista Docência e Cibercultura 2023-07-05

Visualization and clear understanding of the ovarian structures are important in determining stage oestrus, helping to diagnose several pathologies supporting advances reproductive technologies. In this research, computerized microtomography (microCT) was used explore characterize structure seven mammalian species. Ovaries rats, female dog, queens, cows, mares, sows a donkey were used. After microCT scanning, same samples prepared for histologic evaluation, here as validation criterion. It...

10.1590/0001-3765201720150864 article EN cc-by Anais da Academia Brasileira de Ciências 2017-06-29
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