Charles H. King

ORCID: 0000-0003-1409-4549
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About
Contact & Profiles
Research Areas
  • Scientific Computing and Data Management
  • Research Data Management Practices
  • Gut microbiota and health
  • Psychotherapy Techniques and Applications
  • Cell Image Analysis Techniques
  • Child Therapy and Development
  • Distributed and Parallel Computing Systems
  • Inflammatory mediators and NSAID effects
  • Insect behavior and control techniques
  • Bacteriophages and microbial interactions
  • Cancer Genomics and Diagnostics
  • RNA modifications and cancer
  • Probiotics and Fermented Foods
  • Online and Blended Learning
  • Clostridium difficile and Clostridium perfringens research
  • Virus-based gene therapy research
  • Legal Education and Practice Innovations
  • Genetics, Bioinformatics, and Biomedical Research
  • Social Work Education and Practice
  • Neurobiology and Insect Physiology Research
  • Advanced biosensing and bioanalysis techniques
  • Psychological Well-being and Life Satisfaction
  • Autism Spectrum Disorder Research
  • Psychopathy, Forensic Psychiatry, Sexual Offending
  • Behavioral and Psychological Studies

George Washington University
2017-2025

University of California, Irvine
2025

Washington University Medical Center
2017-2022

McCormick (United States)
2017-2022

University of Southern Mississippi
2005

Youth Development
1976

FrontLine Service
1970

New York Medical College
1970

Metropolitan Hospital Center
1970

Community Service Society
1957-1959

A comprehensive knowledge of the types and ratios microbes that inhabit healthy human gut is necessary before any kind pre-clinical or clinical study can be performed attempts to alter microbiome treat a condition improve therapy outcome. To address this need we present an innovative scalable analysis workflow, reference list abundance profile (GutFeelingKB), novel Fecal Biome Population Report (FecalBiome) with applicability. GutFeelingKB provides 157 organisms (8 phyla, 18 classes, 23...

10.1371/journal.pone.0206484 article EN public-domain PLoS ONE 2019-09-11

The Playbook Workflow Builder (PWB) is a web-based platform to dynamically construct and execute bioinformatics workflows by utilizing growing network of input datasets, semantically annotated API endpoints, data visualization tools contributed an ecosystem collaborators. Via user-friendly user interface, can be constructed from building-blocks without technical expertise. output each step the workflow added into reports containing textual descriptions, figures, tables, references. To...

10.1371/journal.pcbi.1012901 article EN cc-by PLoS Computational Biology 2025-04-03

PURPOSE The purpose of OncoMX 1 knowledgebase development was to integrate cancer biomarker and relevant data types into a meta-portal, enabling the research biomarkers side by with other pertinent multidimensional types. METHODS Cancer mutation, differential expression, expression specificity, healthy gene from human mouse, literature mining for mutation were integrated, unified biomedical ontologies, subjected rule-based automated quality control before ingestion database. RESULTS provides...

10.1200/cci.19.00117 article EN cc-by JCO Clinical Cancer Informatics 2020-03-06

Youths committing homicides or other acts of violence appear to be increasing in number at an alarming rate, causing mounting concern society and pressure upon those charged with their rehabilitation. Nine such youths were studied define similar parameters each around which a viable theory causality could delineated, approach treatment designed.

10.1111/j.1939-0025.1975.tb01174.x article EN American Journal of Orthopsychiatry 1975-01-01

Variant calling is hindered in segmental duplications by sequence homology. We developed Paraphase, a HiFi-based informatics method that resolves highly similar genes phasing all haplotypes of paralogous together. applied Paraphase to 160 long (>10 kb) duplication regions across the human genome with high (>99%) similarity, encoding 316 genes. Analysis five ancestral populations revealed variable copy numbers these regions. identified 23 paralog groups exceptionally low within-group...

10.1038/s41467-025-57505-2 article EN cc-by-nc-nd Nature Communications 2025-03-08

A personalized approach based on a patient's or pathogen’s unique genomic sequence is the foundation of precision medicine. Genomic findings must be robust and reproducible, experimental data capture should adhere to findable, accessible, interoperable, reusable (FAIR) guiding principles. Moreover, effective medicine requires standardized reporting that extends beyond wet-lab procedures computational methods. The BioCompute framework (https://w3id.org/biocompute/1.3.0) enables provenance,...

10.1371/journal.pbio.3000099 article EN public-domain PLoS Biology 2018-12-31

There are hundreds of children who present a combination childish dependency and negativistic bravado. They full resourcefulness cunning about how to get along in the streets, yet they hopelessly ignorant illiterate after six grades public school. demand constant gratification but do not admit being gratified. This chapter is confined two areas, namely, what authors have observed families function, adaptations therapeutic technique devised for clinical work with them. The author's first job...

10.1111/j.1939-0025.1964.tb02200.x article EN American Journal of Orthopsychiatry 1964-01-01

MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 286:203-215 (2005) - doi:10.3354/meps286203 Molecular indicators of hypoxia in blue crab Callinectes sapidus Nancy J. Brown-Peterson1, Patrick Larkin2, Denslow3, Christina King1, Steve Manning1, Marius Brouwer1,* 1Department Coastal Sciences, The University Southern Mississippi, 703 East Beach Dr., Ocean...

10.3354/meps286203 article EN Marine Ecology Progress Series 2005-01-01

The volume of nucleic acid sequence data has exploded recently, amplifying the challenge transforming into meaningful information. Processing can require an increasingly complex ecosystem customized tools, which increases difficulty in communicating analyses understandable way yet is sufficient detail to enable informed decisions or repeats. This be particular interest institutions and companies computations a regulatory environment. BioCompute Objects (BCOs; instance pipeline documentation...

10.1016/j.drudis.2024.103884 article EN cc-by Drug Discovery Today 2024-01-19

Developments in high-throughput sequencing (HTS) result an exponential increase the amount of data generated by experiments, complexity bioinformatics analysis reporting and types generated. These increases volume, diversity their expose necessity a structured standardized template. BioCompute Objects (BCOs) provide requisite support for communication HTS that includes workflow, as well data, curation, accessibility reproducibility communication. BCOs standardize how researchers report...

10.1093/database/baab008 article EN cc-by Database 2021-01-01

Youth in Crisis. A Radical Approach to Delinquency. By Otto L. Shaw. New York: Hart Publishing Co. $4.95, Street Gang Work: Theory and Practice. Irving Spergel. Reading, Mass.: Addison-Wesley $5.95 Get access Shaw L.. Co., 1966. 192 pp. $4.95Street Spergel Irving. 250 Charles H. King Wiltwyck School for BoysNew York, York Search other works by this author on: Oxford Academic PubMed Google Scholar Social Work, Volume 12, Issue 4, October 1967, Pages 114–115,...

10.1093/sw/12.4.114 article EN Social Work 1967-10-01

10.1080/00207284.1959.11508072 article EN International Journal of Group Psychotherapy 1959-04-01

The constant confrontation inherent in therapeutic intervention with violence prone children, some of whome have committed homicide, is explored. Problems unique to work these youths are discussed terms counter-transference issues for clinicians and counter-experience teachers child care workers. Suggestions training supervision offered.

10.1111/j.1939-0025.1976.tb01226.x article EN American Journal of Orthopsychiatry 1976-01-01

10.1177/104438945904000404 article EN Families in Society The Journal of Contemporary Social Services 1959-04-01

Sucralose and acesulfame-potassium consumption alters gut microbiota in rodents, with unclear effects humans. We examined of three-times daily sucralose- acesulfame-potassium-containing diet soda for 1 (

10.1139/apnm-2022-0471 article EN Applied Physiology Nutrition and Metabolism 2023-10-30

A comprehensive knowledge of the types and ratios microbes that inhabit healthy human gut is necessary before any kind pre-clinical or clinical study can be performed attempts to alter microbiome treat a condition improve therapy outcome. To address this need we present an innovative scalable analysis workflow, reference list abundance profile (GutFeelingKB), novel Fecal Biome Population Report (FecalBiome) with applicability. GutFeelingKB provides 157 organisms (8 phyla, 18 classes, 23...

10.1101/445353 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2018-10-16

10.1080/00207284.1970.11491792 article EN International Journal of Group Psychotherapy 1970-10-01

(1957). The Role of Visitors in Activity Group Therapy. International Journal Psychotherapy: Vol. 7, No. 3, pp. 289-301.

10.1080/00207284.1957.11508750 article EN International Journal of Group Psychotherapy 1957-07-01

Abstract Many biomedical research projects produce large-scale datasets that may serve as resources for the community hypothesis generation, facilitating diverse use cases. Towards goal of developing infrastructure to support findability, accessibility, interoperability, and reusability (FAIR) digital objects maximally extracting knowledge from data, complex queries span across data tools multiple are currently not easily possible. By utilizing existing FAIR application programming...

10.1101/2024.06.08.598037 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2024-06-09

Abstract Background The field of bioinformatics has grown at such a rapid pace that gap in standardization exists when reporting an analysis. In response, the BioCompute project was created to standardize type and method information communicated describing bioinformatic Once became established, its goals shifted broadening awareness usage BioCompute, soliciting feedback from larger audience. To address these goals, collaborated with precisionFDA on crowdsourced challenge ran May 2019 October...

10.1101/2020.11.02.365528 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2020-11-04

10.1177/104438946704800401 article EN Families in Society The Journal of Contemporary Social Services 1967-04-01
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