A5078740482- Bacteriophages and microbial interactions
- Genomics and Phylogenetic Studies
- HIV Research and Treatment
- Clostridium difficile and Clostridium perfringens research
- Virus-based gene therapy research
- Gut microbiota and health
- RNA modifications and cancer
- Molecular Biology Techniques and Applications
- RNA and protein synthesis mechanisms
- Colorectal Cancer Screening and Detection
- Evolution and Genetic Dynamics
- Advanced biosensing and bioanalysis techniques
- Bioinformatics and Genomic Networks
- Algorithms and Data Compression
- Glycosylation and Glycoproteins Research
- Plant Virus Research Studies
- Probiotics and Fermented Foods
- Cancer-related gene regulation
George Washington University
2015-2024
Washington University Medical Center
2016-2019
McCormick (United States)
2015
A comprehensive knowledge of the types and ratios microbes that inhabit healthy human gut is necessary before any kind pre-clinical or clinical study can be performed attempts to alter microbiome treat a condition improve therapy outcome. To address this need we present an innovative scalable analysis workflow, reference list abundance profile (GutFeelingKB), novel Fecal Biome Population Report (FecalBiome) with applicability. GutFeelingKB provides 157 organisms (8 phyla, 18 classes, 23...
BioXpress is a gene expression and cancer association database in which the levels are mapped to genes using RNA-seq data obtained from The Cancer Genome Atlas, International Consortium, Expression Atlas publications. includes 64 types, 6361 patients 17 469 with 9513 of displaying differential between tumor normal samples. In addition directly retrieved repositories, manual biocuration publications supplements available annotations database. All types Disease Ontology terms facilitate...
The High-performance Integrated Virtual Environment (HIVE) is a distributed storage and compute environment designed primarily to handle next-generation sequencing (NGS) data. This multicomponent cloud infrastructure provides secure web access for authorized users deposit, retrieve, annotate on NGS data, analyse the outcomes using interface visual environments appropriately built in collaboration with research regulatory scientists other end users. Unlike many massively parallel computing...
The volume of nucleic acid sequence data has exploded recently, amplifying the challenge transforming into meaningful information. Processing can require an increasingly complex ecosystem customized tools, which increases difficulty in communicating analyses understandable way yet is sufficient detail to enable informed decisions or repeats. This be particular interest institutions and companies computations a regulatory environment. BioCompute Objects (BCOs; instance pipeline documentation...
A comprehensive knowledge of the types and ratios microbes that inhabit healthy human gut is necessary before any kind pre-clinical or clinical study can be performed attempts to alter microbiome treat a condition improve therapy outcome. To address this need we present an innovative scalable analysis workflow, reference list abundance profile (GutFeelingKB), novel Fecal Biome Population Report (FecalBiome) with applicability. GutFeelingKB provides 157 organisms (8 phyla, 18 classes, 23...
High-throughput sequencing (HTS) has been widely used to characterize HIV-1 genome sequences. There are no algorithms currently that can directly determine genotype and quasispecies population using short HTS reads generated from long sequences without additional software. To establish a robust subpopulation, subtype, recombination analysis workflow, we amplified the 3'-half plasma samples of 65 HIV-1-infected individuals sequenced entire amplicon (∼4,500 bp) by HTS. With direct raw...
Abstract The volume of nucleic acid sequence data has exploded in recent years, and with it, the challenge finding transforming relevant into meaningful information. Processing abundance can require a dynamic ecosystem customized tools. As analysis pipelines become more complex, there is an increased difficulty communicating details way that understandable yet sufficient detail to make informed decisions about results or repeat analysis. This may be particular interest institutions private...