Qian Wu

ORCID: 0000-0003-1435-681X
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About
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Research Areas
  • Lubricants and Their Additives
  • Tribology and Wear Analysis
  • Neurological Disease Mechanisms and Treatments
  • Traditional Chinese Medicine Analysis
  • Advancements in Transdermal Drug Delivery
  • Plant-based Medicinal Research
  • Orthopaedic implants and arthroplasty
  • Advanced Glycation End Products research
  • Botulinum Toxin and Related Neurological Disorders
  • Metabolomics and Mass Spectrometry Studies
  • Diamond and Carbon-based Materials Research
  • Tribology and Lubrication Engineering

Anhui University of Traditional Chinese Medicine
2022-2024

The service life of artificial joints has gradually failed to meet the needs patients. Herein, synergistic lubrication and antioxidant efficacies graphene oxide (GO) fullerenol (Fol) as biological lubricant additives for were investigated. mechanisms containing GO Fol at friction interface then revealed. Tribological tests showed that average coefficients Al2O3–Ti6Al4V pairs Ti6Al4V–UHMWPE could be reduced by 30% 22%, respectively, when used simultaneously. mechanism some incommensurate...

10.3390/lubricants11010011 article EN cc-by Lubricants 2022-12-30

To investigate the protective effect of Tongqiao Huoxue Decoction containing cerebrospinal fluid(TQHXD-CSF) on HT22 cells damaged by oxygen-glucose deprivation/reoxygenation(OGD/R) and whether mechanism is related to regulation ASK1/MKK4/JNK signaling pathway. were subjected OGD/R simulate cerebral ischemia-reperfusion injury(CIRI). Then randomly divided into five groups: blank fluid(control group), group, TQHXD-CSF Z-VAD-FMK group(20 μmol·L~(-1)) TQHXD-CSF+Z-VAD-FMK group. Except control in...

10.19540/j.cnki.cjcmm.20220509.701 article EN PubMed 2022-10-01

Mitochondrion, as the main energy-supply organelle, is key target region that determines neuronal survival and death during ischemia. When an ischemic stroke occurs, timely removal of damaged mitochondria very important for improving mitochondrial function repairing nerve damage. This study investigated effect ligustilide(LIG), active ingredient Chinese medicine, on mitophagy based oxygen glucose deprivation/reperfusion(OGD/R)-induced injury model in HT22 cells. By OGD/R-induced was induced...

10.19540/j.cnki.cjcmm.20211029.404 article EN PubMed 2022-04-01
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