A5031009976- Antifungal resistance and susceptibility
- Advanced Glycation End Products research
- Fungal and yeast genetics research
- Natural Antidiabetic Agents Studies
- Asthma and respiratory diseases
- Mycotoxins in Agriculture and Food
- Phytochemicals and Antioxidant Activities
- Chromatography in Natural Products
- Microbial Natural Products and Biosynthesis
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Trace Elements in Health
- Engineering Applied Research
- Pickering emulsions and particle stabilization
- Membrane-based Ion Separation Techniques
- Graphene and Nanomaterials Applications
- Polysaccharides Composition and Applications
- Animal Behavior and Welfare Studies
- Heat transfer and supercritical fluids
- Environmental remediation with nanomaterials
- Entomopathogenic Microorganisms in Pest Control
- Food Industry and Aquatic Biology
- Neurological Disease Mechanisms and Treatments
- Herbal Medicine Research Studies
- Inflammatory mediators and NSAID effects
- Probiotics and Fermented Foods
University of Wisconsin–Madison
2017-2024
Acorn
2024
Hubei University of Technology
2023
China University of Mining and Technology
2023
Lanzhou University of Technology
2023
Institute of Electronics
2020
University of Chinese Academy of Sciences
2020
Dalian University
2019
Dalian University of Technology
2019
The Fenton-chemistry-generating properties of copper ions are considered a potent phagolysosome defense against pathogenic microbes, yet our understanding underlying host/microbe dynamics remains unclear. We address this issue in invasive aspergillosis and demonstrate that host fungal responses inextricably connect reactive oxygen intermediate (ROI) mechanisms. Loss the copper-binding transcription factor AceA yields an Aspergillus fumigatus strain displaying increased sensitivity to ROI...
Abstract We inhale respiratory pathogens continuously, and the subsequent signaling events between host microbe are complex, ultimately resulting in clearance of microbe, stable colonization host, or active disease. Traditional vitro methods ill-equipped to study these critical context lung microenvironment. Here we introduce a microscale organotypic model human bronchiole for studying pulmonary infection. By leveraging techniques, is designed approximate structure bronchiole, containing...
Accumulation of advanced glycation end products (AGEs) is linked with development or aggravation many degenerative processes disorders. Fruit vinegars are rich in polyphenols that can be a good dietary source AGEs inhibitors. In this study, eight kinds were prepared. Among them, the highest polyphenol and flavonoid content orange vinegar kiwi fruit vinegar, respectively. Ferulic acid, vanillic chlorogenic p-coumaric caffeic catechin, epicatechin main vinegars. Then, we measured inhibitory...
Abstract Filamentous fungi differentiate along complex developmental programs directed by abiotic and biotic signals. Currently, intrinsic signals that govern fungal development remain largely unknown. Here we show an endogenously produced secreted oxylipin, 5,8-diHODE, induces cellular differentiation, including lateral branching in pathogenic Aspergillus fumigatus flavus , appressorium formation the rice blast pathogen Magnaporthe grisea . The response is specific to a subset of oxylipins...
Invasive aspergillosis is a common opportunistic infection, causing >50% mortality in infected immunocompromised patients. The specific molecular mechanisms of the innate immune system that prevent pathogenesis invasive immunocompetent individuals are not fully understood. Here, we used zebrafish larva-Aspergillus infection model to identify cyclooxygenase (COX) enzyme signaling as one mechanism promotes host survival. Larvae exposed pan-COX inhibitor indomethacin succumb at significantly...
is a ubiquitous opportunistic pathogen. We have previously reported that volatile organic compounds (VOCs) produced by
Protein-AGEs (advanced glycation end products) were prepared and characterized by glucose (Glu) soy protein isolates (SPI) from food. Mango vinegar (MV) its bio-phenols components explored in the inhibition of degree hydrolysis (DH) protein-AGEs, fluorescent AGEs, non-fluorescent N(ε)-carboxymethyl-lysine (CML) oligopeptide-AGEs released during gastrointestinal digestion. Furthermore, mechanism MV on protein-AGEs digestion was enzyme activity, molecular docking, Fourier transform infrared...
Background Aspergillus fumigatus is a well-known opportunistic pathogen that causes range of diseases including the often-fatal disease, invasive pulmonary aspergillosis (IPA), in immunocompromised populations. The severity IPA dependent on both host- and pathogen-derived signaling molecules mediate host immunity fungal growth. Oxylipins are bioactive oxygenated fatty acids known to influence immune response developmental programs. synthesizes 8-HODE 5,8-diHODE have structural similarities...
Procyanidin-amino acid interactions during transmembrane transport cause changes in the structural and physical properties of peptides, which limits further absorption oligopeptide-advanced glycation end products (AGEs).
Fungi have historically been the source of numerous important medicinal compounds, but full exploitation their genetic potential for drug development has hampered in traditional discovery paradigms. Here we describe a radically different approach, top-down (TD
can cause invasive pulmonary aspergillosis (IPA). Fungicidal azoles and fungistatic caspofungin (CAS) are the first- second-line therapies, respectively, used to treat IPA. Treatment of
A novel and environmentally friendly magnetic iron zeolite (MIZ) core-shell were successfully fabricated using municipal solid waste incineration bottom ash-derived (MWZ) coated with Fe3O4 innovatively investigated as a heterogeneous persulfate (PS) catalyst. The morphology structure composition of as-prepared catalysts characterised, it was proved that the MIZ synthesised by coating uniformly on MWZ surface. tetracycline hydrochloride (TCH) degradation experiment indicate optimum equimolar...
Programmable logic controller (PLC) is an industrial digital computer that has been ruggedized and adapted for the control of manufacturing processes, such as automobile manufacture, or gas pipelines, power generation. Due to closed source vendor-specific proprietary firmware, it difficult develop a scalable high-interaction honeypot PLCs. In this paper, we present discuss new PLC framework based on physical devices. This aims solve problems existing honeypots while providing advantages...
The rapid performance improvement of photovoltaic/thermal (PV/T) implies great potential application to various aspects society. previously developed micro heat pipe PV/T (MHP-PV/T) has shown favorable cogeneration electricity and in cold regions (Li et al. 2022), while it is badly needed improve its comprehensive by enhancement transfer. For same working fluid as HCFC141b pipe, higher Reynolds Number (Re) theoretically means better Therefore, two available pipes were with trapezoidal cross...
PV/T systems could convert solar energy into high-grade electrical and thermal energy, which has significant application value in various aspects such as environment, lifestyle, economy. Our previous research finds that new-developed micro heat pipe system demonstrate great capabilities combined power generation cold regions while it is still of potential to improve overall thermoelectric performance by way transfer enhancement. It necessary investigate the influence different working fluids...