A5082723909- Advanced Glycation End Products research
- Protein Hydrolysis and Bioactive Peptides
- Food Quality and Safety Studies
- Phytochemicals and Antioxidant Activities
- Natural Antidiabetic Agents Studies
- Fermentation and Sensory Analysis
- Tea Polyphenols and Effects
- Proteins in Food Systems
- Food composition and properties
- Probiotics and Fermented Foods
- Biochemical effects in animals
- Genetics, Aging, and Longevity in Model Organisms
- Selenium in Biological Systems
- Microbial Metabolites in Food Biotechnology
- Microbial Metabolism and Applications
- Genomics and Phylogenetic Studies
- Phytoestrogen effects and research
- Biofuel production and bioconversion
- Protist diversity and phylogeny
- Advanced Cellulose Research Studies
- Biochemical and biochemical processes
- Microbial Metabolic Engineering and Bioproduction
- Food Industry and Aquatic Biology
- Fungal Biology and Applications
- Botanical Research and Applications
Hubei University of Technology
2016-2025
Agriculture and Agri-Food Canada
2014-2021
Beijing Technology and Business University
2020
Center of Hubei Cooperative Innovation for Emissions Trading System
2019
Jiangnan University
2014-2018
State Key Laboratory of Food Science and Technology
2014-2018
Accumulation of advanced glycation end products (AGEs) is linked with development or aggravation many degenerative processes disorders. Fruit vinegars are rich in polyphenols that can be a good dietary source AGEs inhibitors. In this study, eight kinds were prepared. Among them, the highest polyphenol and flavonoid content orange vinegar kiwi fruit vinegar, respectively. Ferulic acid, vanillic chlorogenic p-coumaric caffeic catechin, epicatechin main vinegars. Then, we measured inhibitory...
Background The nematode Caenorhabditis elegans has become increasingly used for screening antimicrobials and probiotics pathogen control. It also provides a useful tool studying microbe-host interactions. This study established C. life-span assay to preselect probiotic bacteria controlling K88+ enterotoxigenic Escherichia coli (ETEC), causing pig diarrhea, determined potential mechanism underlying the protection provided by Lactobacillus. Methodology/Principal Findings Life-span of was...
Listeria monocytogenes is a food-borne pathogen that seriously threatens human health. We analyzed the antibacterial activity and mechanism of δ-cadinene against L. monocytogenes. The effect on gene expression was investigated using RNA sequencing. δ-Cadinene inhibited growth at minimum inhibitory concentration 5 μL/mL bactericidal 10 μL/mL. In addition, suppressed biofilm formation, altered cell morphology, damaged membrane monocytogenes, enhancing permeability affecting potential. Of note,...
A schematic of the potential mechanism HGD228 supplementation in alleviating HSD-exacerbated UC.
Enterotoxigenic Escherichia coli (ETEC) infection causes the death of Caenorhabditis elegans, which can be prevented by certain Lactobacillus isolates. The host response C. elegans to ETEC and its regulation isolates are, however, largely unclear. This study has revealed that, in agreement with results life-span assays, expression genes encoding p38 mitogen-activated protein kinase (MAPK) pathway (nsy-1, sek-1, pmk-1), insulin/insulin-like growth factor (DAF/IGF) (daf-16), or antimicrobial...
Abstract Pygo2 has been discovered as an important Wnt signaling component contributing to the activation of Wnt-target gene transcription. In present study, we that mRNA and protein levels were up-regulated in majority (152/209) human brain glioma tissues five cell lines significantly correlated with age, WHO tumor classification poor patient survival. The histone methyltransferase complex components (WDR5, Ash2 menin, but not CXCC1 or NCOA6) down-regulated at promoter loci target genes...
Catechin has a good inhibitory effect on advanced glycation end product (AGE) formation in alcoholic media, which is generated by Maillard reaction closely related to diabetes.
Glycated proteins are the main source of dietary advanced glycation end products (AGEs). enzymatically hydrolyzed in gastrointestinal tract, which releases more absorbable and smaller potentially harmful AGEs. This study investigated inhibitory effect catechin on AGE release from glycated bovine serum albumin (G-BSA) during digestion. Catechin inhibited digestion, especially gastric digestion stage. Additionally, altered these peptides small intestine by reducing G-BSA digestibility. The...
The inhibitory activity of lactic acid bacteria (LAB) toward advanced glycation end-products (AGEs) during vinegar fermentation was studied, and its relationships with the substrate consumption, antioxidant capacity, total phenolic content, flavonoid compounds, α-glucosidase, α-amylase inhibition were evaluated. made from rice powder flour by liquid-state (LSF). selected LAB strains separately co-cultivated Saccharomyces cerevisiae Acetobacter pasteurianus 1.41 in alcoholic acetic...
Herpes simplex virus type 1 (HSV‐1), a member of the viridae, is associated with wide variety nervous system diseases including meningitis and encephalitis. The data presented here demonstrate that miR‐649 promotes replication HSV‐1 without affecting cell viability. Further mechanistic studies revealed MALT1 (mucosa lymphoid tissue lymphoma translocation gene 1) directly targeted by miR‐649. We then found downstream NF‐κB signaling pathway, are involved in miR‐649‐induced replication....
Summary Soy sauce contains a number of bioactive components, which have been shown to possess strong antioxidative properties. The objective this study was compare the enzyme activities, antioxidant activity and phenolic compounds content soy sauces prepared from mixed koji (SSAON, inoculated with Aspergillus oryzae HG‐26 niger HG‐35), those made culture containing only (SSAO). total (TPC), flavonoid (TFC), three isoflavone aglycones (daizein, glycitein genistein) SSAON were found be higher...
Lactobacillus fermentum (L. fermentum) was first evaluated as a potential advanced glycation end-product (AGE) formation inhibitor by establishing bovine serum albumin (BSA) + glucose (glu) model in the present study. The results showed that highest inhibition rates of pentosidine and total fluorescent AGEs L. were approximately 51.67% 77.22%, respectively, which higher than aminoguanidine (AG). Mechanistic analysis could capture methylglyoxal glyoxal, inhibit carbonyl sulfhydryl oxidation,...