A5077947981- Proteins in Food Systems
- Genetics, Aging, and Longevity in Model Organisms
- Polysaccharides and Plant Cell Walls
- Polysaccharides Composition and Applications
- Probiotics and Fermented Foods
- Sirtuins and Resveratrol in Medicine
- Meat and Animal Product Quality
- Food composition and properties
- Adipose Tissue and Metabolism
- Nanocomposite Films for Food Packaging
- Protein Hydrolysis and Bioactive Peptides
- Tea Polyphenols and Effects
- Biochemical effects in animals
- Microencapsulation and Drying Processes
- Food Chemistry and Fat Analysis
- Phytochemicals and Antioxidant Activities
- Bee Products Chemical Analysis
- Pineapple and bromelain studies
- Muscle Physiology and Disorders
- Edible Oils Quality and Analysis
- Advanced Glycation End Products research
- Advanced Sensor and Energy Harvesting Materials
- Postharvest Quality and Shelf Life Management
- Circadian rhythm and melatonin
- Phytase and its Applications
University of Massachusetts Amherst
2015-2024
North Dakota State University
2019-2022
Southwest Minnesota State University
2020-2021
Amherst College
2019
State Key Laboratory of Food Science and Technology
2013
Nanchang University
2013
Major polyphenolic compounds in pineapple peels were identified and quantified. The antioxidant capacities of peel extracts these determined using DPPH• scavenging capacity phosphomolybdenum method. Effects polyphenolics' interactions on their also evaluated. Gallic acid (31.76 mg/100 g dry extracts), catechin (58.51 g), epicatechin (50.00 ferulic (19.50 g) found to be the main polyphenolics peels. IC50 for assay was 1.13 mg/ml total 0.037 ascorbic equivalents/g. order per mole present...
Abstract Current therapies for Duchenne muscular dystrophy (DMD) use phosphorodiamidate morpholino oligomers (PMO) to induce exon skipping in the dystrophin pre-mRNA, enabling translation of a shortened but functional protein. This strategy has been hampered by insufficient delivery PMO cardiac and skeletal muscle. To overcome these limitations, we developed FORCETM platform consisting an antigen-binding fragment, which binds transferrin receptor 1, conjugated oligonucleotide. We demonstrate...
The interaction between lactic acid bacteria (LAB) and curcumin can influence bioactivity; however, the strain-specific metabolic transformations of by LAB remain unclear. In our study, two exhibiting distinct activities on were selected: Lactobacillus gasseri ATCC 33323 (LM) could metabolize curcumin, while Limosilactobacillus reuteri 23272 (LUM) not. Liquid chromatography-mass spectrometry (LC-MS) analysis showed that LUM preserved curcumin's native form, whereas LM metabolized it...
<italic>trans</italic>-Trismethoxy resveratrol reduced fat accumulation <italic>via</italic> the regulation of FAT-6 and FAT-7, stearoyl-CoA desaturases homologs, in <italic>Caenorhabditis elegans</italic>.
Epigallocatechin gallate (EGCG) is a polyphenol that abundant in green tea. It has been reported consumption of EGCG can contribute to weight loss, however, the underlying mechanism not fully understood. To determine how reduces body fat, an organism model Caenorhabditis elegans was used, which useful animal system exploring crucial biological mechanisms are readily applicable humans. In this study, different strains were raised for two days on Escherichia coli OP 50 diet with or without 100...
Salt, most often sodium chloride (NaCl), is commonly used in a variety of food emulsions. However, little known about the detailed mechanism how NaCl influences lipid oxidation and thus shelf life those products. In this study, we report new through which could help inhibit dodecyl sulfate (SDS)-stabilized oil-in-water (O/W) Results showed that significantly lowered critical micelle concentration (CMC) SDS, further led to greater amounts hydroperoxides being solubilized by SDS micelles into...
The covalent interactions between proanthocyanidins (PAs) and pectin during thermal processing was investigated. An acid-butanol assay clearly showed that PAs were covalently bound to pectin. Computational studies indicated a nucleophilic substitution reaction occurred the carbocation generated by carboxyl or hydroxyl groups on pectin, leading formation of PAs-pectin adducts. Thermal significantly affected physicochemical, functional, biological properties reduced molecular weight increased...
Excess fat accumulation and abnormal lipid glucose metabolism are linked to numerous diseases, including type 2 diabetes. To identify natural bioactive compounds that modulate storage, we used the nematode model ( C. elegans ) determine effects of strawberry raspberry phenolic on (total contents were 8.86 ± 0.28 5.54 0.20 μg gallic acid equivalents/ml, respectively). Both extracts significantly decreased triglyceride in wild strain compared controls (by 40% 31%, respectively) without...
Cranberries are rich source of phenolic compounds (i.e. acids, flavonoids, anthocyanidins) and have been linked to many health benefits. A recent report suggested that cranberry bioactives inhibit adipogenesis in 3T3‐L1 cells. Thus, we investigated the mechanisms on lipid metabolism using Caenorhabditis elegans model. We evaluated effects water soluble (contains approximately 6.6% 2.2% flavonoids 0.6% fat accumulation, pumping rate (food intake), locomotive activity wild type (N2). The...