- Epilepsy research and treatment
- Mental Health Research Topics
- Suicide and Self-Harm Studies
- Power Systems and Technologies
- Ophthalmology and Visual Impairment Studies
- Privacy-Preserving Technologies in Data
- Lung Cancer Treatments and Mutations
- Child and Adolescent Psychosocial and Emotional Development
- Thyroid Cancer Diagnosis and Treatment
- Neuroscience and Neuropharmacology Research
- Neurological disorders and treatments
- Radio Frequency Integrated Circuit Design
- High-Voltage Power Transmission Systems
- Colorectal and Anal Carcinomas
- Power Systems and Renewable Energy
- Translation Studies and Practices
- Plant and Fungal Species Descriptions
- Semiconductor materials and devices
- Cancer Diagnosis and Treatment
- EEG and Brain-Computer Interfaces
- Corneal surgery and disorders
- Cancer Genomics and Diagnostics
- Genomics and Phylogenetic Studies
- Advancements in Semiconductor Devices and Circuit Design
- Resilience and Mental Health
Xuzhou Medical College
2022-2025
Fudan University
2009-2025
Dian Diagnostics (China)
2022-2025
Dongyang People's Hospital
2024
China Astronaut Research and Training Center
2024
Inner Mongolia University
2024
Shandong University of Traditional Chinese Medicine
2022-2024
Gansu University of Traditional Chinese Medicine
2024
Yan'an University
2024
Wenzhou Medical University
2024
This study aims to examine the temporal changes in incidence, prevalence, and disability-adjusted life years (DALYs) of depressive disorders as well its association with age, period, birth cohort among Chinese from 1990 2021, forecast future trends incidence rates numbers 2022 2030. Data for analysis were obtained Global Burden Disease (GBD) 2021. Joinpoint was used calculate annual percentage change (APC) average percent (AAPC) describe disorders. Age, model utilized disentangle effects on...
The purpose of this study is to analyze the predictive value neutrophil lymphocyte ratio (NLR), count monocyte (LMR), platelet (PLR), multiplied by (SII), red blood cell distribution width (RDW), packed volume (PCV), and plateletcrit (PCT) levels in advanced non-small lung cancer (NSCLC) patients treated with PD-1/PD-L1 inhibitors. From March 2019 August 2023, we screened 104 153 stage III unresectable local NSCLC IV who received inhibitor therapy at our hospital met inclusion exclusion...
Major polyphenolic compounds in pineapple peels were identified and quantified. The antioxidant capacities of peel extracts these determined using DPPH• scavenging capacity phosphomolybdenum method. Effects polyphenolics' interactions on their also evaluated. Gallic acid (31.76 mg/100 g dry extracts), catechin (58.51 g), epicatechin (50.00 ferulic (19.50 g) found to be the main polyphenolics peels. IC50 for assay was 1.13 mg/ml total 0.037 ascorbic equivalents/g. order per mole present...
High-entropy effect is a novel design strategy to optimize properties and explore materials. In this work, (La<sub>1/5</sub>Nd<sub>1/5</sub>Sm<sub>1/5</sub>Ho<sub>1/5</sub>Y<sub>1/5</sub>)NbO<sub>4</sub> (5RNO) high-entropy microwave dielectric ceramics were successfully prepared in the sintering temperature (S.T.) range of 1210–1290 ℃ via solid-phase reaction route, medium-entropy (La<sub>1/3</sub>Nd<sub>1/3</sub>Sm<sub>1/3</sub>)NbO<sub>4</sub>...
N6-methyladenosine (m
Cholangiocarcinoma, or bile duct cancer, is a gastrointestinal cancer with limited therapeutic options and poor outcome. Studies have revealed that some major driver genes are associated cholangiocarcinoma, but no targeted therapies been approved. Immune checkpoint inhibitors, which represented by inhibitors of programmed cell death 1 (PD-1)/programmed death-ligand (PD-L1), emerged as potential therapy for multiple types solid cancers. A 53-year-old female presented postoperative recurrence...
There has been minimal research on the role of benevolent childhood experiences (BCEs) and how such events may offer protection from insidious effects adverse (ACEs) or later in life.This aims to learn BCEs ACEs interact affect adolescents' psychological distress.Cross-sectional survey was conducted three cities (Xuzhou, Nanjing, Wuhan) China March 2021 May 2021. Latent class analysis (LCA) used classify patterns BCEs. We adopted hierarchical multivariable regression examine influences...
To explore the relationship between non-suicidal self-injury (NSSI) and childhood abuse in transgender people mediating effect of emotional dysregulation traits association self-injury.
Background: Heart failure with preserved ejection fraction (HFpEF) represents a profoundly heterogeneous cardiovascular condition characterized by intricate molecular pathways that have not yet been fully elucidated. This study seeks to uncover metabolic reprogramming-associated key genes (Key Genes) linked HFpEF, investigate their functional significance and influence on the immune microenvironment, establish robust early diagnostic framework. Methods: We obtained datasets GSE194151...
Preoperative ultrasound examination of thyroid nodules is the most economical and effective screening method for diagnosing nodules. Fine-needle aspiration biopsy (FNAB) cytology guided by has high sensitivity specificity in distinguishing benign malignant However, approximately 25% cannot be determined FNAB, accurate differentiation critical patient prognosis. Here, we report diagnosis surgical treatment process a rare with bilateral tumor independent origin. This had significantly elevated...
Objective In order to better investigate the cause/effect relationships of human mesial temporal lobe epilepsy (mTLE), we hereby describe a new non-human primate model mTLE. Methods Ten macaques were studied and divided into 2 groups: saline control group (n = 4) kainic acid (KA) injection 6). All implanted bilaterally with subdural electrodes over cortex depth in CA3 hippocampal region. KA was stereotaxically injected right hippocampus macaques. animals monitored by video...
Physalis alkekengi L. calyx (PC) extract can relieve insulin resistance and has glycemic anti-inflammatory effects; however, the potential mechanisms related to gut microbiota metabolites remain elusive. This study aimed understand how PC regulates exert anti-obesogenic effects resistance. In this study, a high-fat high-fructose (HFHF)-diet-induced obesity C57BL/6J male mice model with glycolipid metabolism dysfunction was established, which supplemented aqueous of daily for 10 weeks. The...
Abstract Background The incidence of mobile phone addiction among adolescents in rural areas China is increasing year by year, and has already exceeded that some cities. And increases the risk anxiety poor sleep. Therefore, this study used network analysis to investigate relationship between symptoms, predictability sleep quality. Methods From September 2021 March 2022, a total 1920 Xuzhou, were included. survey included information on addiction, Network was estimate structure adolescents’...
Abstract Background Programmed cell death protein 1 (PD-1) checkpoint inhibitors such as pembrolizumab are novel therapeutics used to treat various advanced malignancies. Immune-related adverse events common, among the most serious of these toxicities is hemophagocytic lymphohistiocytosis (HLH), which a life-threatening disorder unbridled immune activation but has not been properly established. Methods We have procured first case an aftermath treatment with from Sir Run Shaw Hospital,...
Background: Driver genes are essential predictors of targeted therapeutic efficacy. Detecting driver gene mutations in lung adenocarcinoma (LUAD) patients can help to screen for drugs and improve patient survival benefits. This study aims investigate the mutation characterization their correlation with clinicopathological features LUAD. Methods: A total 440 LUAD were selected from Sir Run Shaw Hospital between July 2019 September 2022. Postoperative tissue specimens analyzed using...