A5100462181- Cancer-related molecular mechanisms research
- Transplantation: Methods and Outcomes
- RNA modifications and cancer
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Inflammatory Bowel Disease
- Ferroptosis and cancer prognosis
- Galectins and Cancer Biology
- Circular RNAs in diseases
- BRCA gene mutations in cancer
- RNA Research and Splicing
- Plant Disease Resistance and Genetics
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Epigenetics and DNA Methylation
- MRI in cancer diagnosis
- Peptidase Inhibition and Analysis
- Radiomics and Machine Learning in Medical Imaging
- Signaling Pathways in Disease
- Head and Neck Cancer Studies
- Celiac Disease Research and Management
- Thyroid Cancer Diagnosis and Treatment
- Infant Nutrition and Health
- Chronic Lymphocytic Leukemia Research
- Inflammasome and immune disorders
- Gastric Cancer Management and Outcomes
- Biomarkers in Disease Mechanisms
Wenzhou Medical University
2025
Ruian People's Hospital
2025
Second Affiliated Hospital of Zhengzhou University
2021-2024
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2024
University of Electronic Science and Technology of China
2024
Shandong University of Traditional Chinese Medicine
2023
Zhengzhou University
2023
Second Hospital of Hebei Medical University
2022
Institute of Animal Science
2022
Shaoxing People's Hospital
2022
Fecal microbiota transplantation (FMT) is currently a promising therapy for inflammatory bowel disease (IBD). However, clinical studies have shown that there an obvious individual difference in the efficacy of FMT. Therefore, it pressing issue to identify factors influence FMT and find ways screen most suitable patients this therapy. In work, we targeted stimulator interferon genes (STING), DNA-sensing protein regulates host-defense. By comparing differential mice with different expression...
Preoperative ultrasound examination of thyroid nodules is the most economical and effective screening method for diagnosing nodules. Fine-needle aspiration biopsy (FNAB) cytology guided by has high sensitivity specificity in distinguishing benign malignant However, approximately 25% cannot be determined FNAB, accurate differentiation critical patient prognosis. Here, we report diagnosis surgical treatment process a rare with bilateral tumor independent origin. This had significantly elevated...
Objective: To investigate the correlations between dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) perfusion histogram parameters and vascular endothelial growth factor (VEGF) epidermal receptor (EGFR) expressions in advanced gastric cancer (AGC). Methods: This retrospective study included 80 pathologically confirmed patients with AGC who underwent DCE-MRI before surgery from February 2017 to May 2021. The were calculated by Omni Kinetics software four quantitative parameter...
Lung cancer has a high mortality rate. Promoting early diagnosis and screening of lung is the most effective way to enhance survival rate patients. Through computer technology, comprehensive evaluation genetic testing results basic clinical information patients could effectively diagnose indicate risks. This study retrospectively collected 70 pairs tissue samples normal human samples. The methylation frequencies 6 genes (FHIT, p16, MGMT, RASSF1A, APC, DAPK) in patients, information, tumor...
Recent studies have emphasized the emerging importance of long noncoding RNAs (lncRNAs) in colorectal cancer (CRC). However, functions and regulatory mechanisms numerous lncRNAs CRC not been fully elucidated.To explore functional role underlying molecular lncRNA TNFRSF10A-AS1 CRC.TNFRSF10A-AS1 expression was measured by quantitative real-time polymerase chain reaction CRC, relationship between levels clinicopathological features patients analyzed. The effect on proliferation metastasis...
Background: Infliximab (IFX) is a potent therapeutic agent used for the treatment of conventional refractory ulcerative colitis (UC). However, high non-response rate IFX brings difficulties to clinical applications. In context proteomics research, our study differentially expressed proteins (DEPs) essential in UC patients and provides powerful insights into underlying drug resistance mechanisms. Methods: A total 12 were divided responders (UCinfG), non-responders (UCinfL), severe (UCsevere)...
Premature ovarian insufficiency(POI)is a female reproductive aging illness. Yiwei decoction(YWD) is traditional treatment for Yangming nourishment. YWD can treat premature insufficiency, but the exact molecular mechanism unknown. As result, differential expression of Long noncoding RNAs (LncRNAs) and Circular RNAs(CircRNAs) in ovary POI rats after was investigated this paper, CeRNA regulatory network built.The model created using cyclophosphamide. The group + Group A, control B, regular C....
Dysfunctional long non-coding RNAs (lncRNAs) have been found to carcinogenic and/or tumor inhibitory effects in the development and progression of cancer, suggesting their potential as new independent biomarkers for cancer diagnosis prognosis. The exploration relationship between lncRNAs overall survival (OS) different cancers opens up prospects treatment. In this study, we established a five-lncRNA signature explored its prognostic efficiency gastric (GC) several thoracic malignancies,...
Abstract Background Infliximab (IFX), the mainstay of current treatment for moderate-to-severe Crohn's disease (CD), markedly improved clinical symptoms and quality life patients. However, not all patients can benefit from IFX. This study aims to identify new therapeutic targets primary nonresponders through combination transcriptomic proteomic analyses. Methods The plasma peripheral leukocytes were collected seven good responders four with CD. To differentially expressed genes (DEGs)...